Fasting activates macroautophagy in neurons of Alzheimer’s disease mouse model but is insufficient to degrade amyloid-beta von Chen, Xigui, Kondo, Kanoh, Motoki, Kazumi, Homma, Hidenori, Okazawa, Hitoshi

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Expanded Newborn Screening for Inborn Errors of Metabolism and Genetic Characteristics in a Chinese Population von Guo, Kejian, Zhou, Xuan, Chen, Xigui, Wu, Yili, Liu, Chuanxin, Kong, Qingsheng

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The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology von Tanaka, Hikari, Kondo, Kanoh, Chen, Xigui, Homma, Hidenori, Tagawa, Kazuhiko, Kerever, Aurelian, Aoki, Shigeki, Saito, Takashi, Saido, Takaomi, Muramatsu, Shin-ichi, Fujita, Kyota, Okazawa, Hitoshi

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Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule von Yoshida, Tomoyuki, Shiroshima, Tomoko, Lee, Sung-Jin, Yasumura, Misato, Uemura, Takeshi, Chen, Xigui, Iwakura, Yoichiro, Mishina, Masayoshi

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Methods to Image Macroautophagy in the Brain In Vivo von Chen, Xigui, Kondo, Kanoh, Okazawa, Hitoshi

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Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology von Mao, Ying, Chen, Xigui, Xu, Min, Fujita, Kyota, Motoki, Kazumi, Sasabe, Toshikazu, Homma, Hidenori, Murata, Miho, Tagawa, Kazuhiko, Tamura, Takuya, Kaye, Julia, Finkbeiner, Steven, Blandino, Giovanni, Sudol, Marius, Okazawa, Hitoshi

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Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology von Fujita, Kyota, Chen, Xigui, Homma, Hidenori, Tagawa, Kazuhiko, Amano, Mutsuki, Saito, Ayumu, Imoto, Seiya, Akatsu, Hiroyasu, Hashizume, Yoshio, Kaibuchi, Kozo, Miyano, Satoru, Okazawa, Hitoshi

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Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight von Bannai, Taro, Mano, Tatsuo, Chen, Xigui, Ohtomo, Gaku, Ohtomo, Ryo, Tsuchida, Takeyuki, Koshi-Mano, Kagari, Hashimoto, Tadafumi, Okazawa, Hitoshi, Iwatsubo, Takeshi, Tsuji, Shoji, Toda, Tatsushi, Iwata, Atsushi

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HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin‐1 knock‐in mice von Ito, Hikaru, Fujita, Kyota, Tagawa, Kazuhiko, Chen, Xigui, Homma, Hidenori, Sasabe, Toshikazu, Shimizu, Jun, Shimizu, Shigeomi, Tamura, Takuya, Muramatsu, Shin‐ichi, Okazawa, Hitoshi

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Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1 von Fujita, Kyota, Mao, Ying, Uchida, Shigenori, Chen, Xigui, Shiwaku, Hiroki, Tamura, Takuya, Ito, Hikaru, Watase, Kei, Homma, Hidenori, Tagawa, Kazuhiko, Sudol, Marius, Okazawa, Hitoshi

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Newborn Screening for Spinal Muscular Atrophy in China Using DNA Mass Spectrometry von Lin, Yiming, Lin, Chien-Hsing, Yin, Xiaoshan, Zhu, Lin, Yang, Jianbin, Shen, Yuyan, Yang, Chiju, Chen, Xigui, Hu, Haili, Ma, Qingqing, Shi, Xueqin, Shen, Yaping, Hu, Zhenzhen, Huang, Chenggang, Huang, Xinwen

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A rare mutation c.1663G > A (p.A555T) in the MMUT gene associated with mild clinical and biochemical phenotypes of methylmalonic acidemia in 30 Chinese patients von Liang, Lili, Shuai, Ruixue, Yu, Yue, Qiu, Wenjuan, Shen, Linghua, Wu, Shengnan, Wei, Haiyan, Chen, Yongxing, Yang, Chiju, Xu, Peng, Chen, Xigui, Zou, Hui, Feng, Jizhen, Niu, Tingting, Hu, Haili, Ye, Jun, Zhang, Huiwen, Lu, Deyun, Gong, Zhuwen, Zhan, Xia, Ji, Wenjun, Yu, Yongguo, Gu, Xuefan, Han, Lianshu

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RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair von Taniguchi, Juliana Bosso, Kondo, Kanoh, Fujita, Kyota, Chen, Xigui, Homma, Hidenori, Sudo, Takeaki, Mao, Ying, Watase, Kei, Tanaka, Toshihiro, Tagawa, Kazuhiko, Tamura, Takuya, Muramatsu, Shin-Ichi, Okazawa, Hitoshi

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Protein tyrosine phosphatase σ regulates the synapse number of zebrafish olfactory sensory neurons von Chen, Xigui, Yoshida, Tomoyuki, Sagara, Hiroshi, Mikami, Yoshinori, Mishina, Masayoshi

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Different mutations in the MMUT gene are associated with the effect of vitamin B12 in a cohort of 266 Chinese patients with mut‐type methylmalonic acidemia: A retrospective study von Yu, Yue, Shuai, Ruixue, Liang, Lili, Qiu, Wenjuan, Shen, Linghua, Wu, Shengnan, Wei, Haiyan, Chen, Yongxing, Yang, Chiju, Xu, Peng, Chen, Xigui, Zou, Hui, Feng, Jizhen, Niu, Tingting, Hu, Haili, Ye, Jun, Zhang, Huiwen, Lu, Deyun, Gong, Zhuwen, Zhan, Xia, Ji, Wenjun, Gu, Xuefan, Han, Lianshu

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Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries von Imamura, Tomomi, Fujita, Kyota, Tagawa, Kazuhiko, Ikura, Teikichi, Chen, Xigui, Homma, Hidenori, Tamura, Takuya, Mao, Ying, Taniguchi, Juliana Bosso, Motoki, Kazumi, Nakabayashi, Makoto, Ito, Nobutoshi, Yamada, Kazunori, Tomii, Kentaro, Okano, Hideyuki, Kaye, Julia, Finkbeiner, Steven, Okazawa, Hitoshi

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Reference Standards for Newborn Screening of Metabolic Disorders by Tandem Mass Spectrometry: A Nationwide Study on Millions of Chinese Neonatal Populations von He, Falin, Yang, Rulai, Huang, Xinwen, Tian, Yaping, Pei, Xiaofang, Bohn, Mary Kathryn, Zou, Lin, Wang, Yan, Li, Haibo, Wang, Ting, Gu, Maosheng, Jiang, Tao, Chen, Xigui, Zou, Hui, Wei, Hongwei, Tian, Weibing, Tang, Tian, Adeli, Khosrow, Wang, Zhiguo

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Cancer-associated fibroblasts promote the proliferation and metastasis of colon cancer by mediating the RLIM/PML axis through paracrine COMP von Chen, Zhenfeng, Chen, Weirong, Lin, Kaihuang, Chen, Xigui, Lin, Guangrong, Li, Yanchong, Cui, Chunhui

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Newborn screening and diagnosis of inborn errors of metabolism: A 5-year study in an eastern Chinese population von Yang, Chiju, Zhou, Cheng, Xu, Peng, Jin, Xianlian, Liu, Wenhua, Wang, Wenjun, Huang, Chenggang, Jiang, Mengyi, Chen, Xigui

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HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease von Fujita, Kyota, Motoki, Kazumi, Tagawa, Kazuhiko, Chen, Xigui, Hama, Hiroshi, Nakajima, Kazuyuki, Homma, Hidenori, Tamura, Takuya, Watanabe, Hirohisa, Katsuno, Masahisa, Matsumi, Chiemi, Kajikawa, Masunori, Saito, Takashi, Saido, Takaomi, Sobue, Gen, Miyawaki, Atsushi, Okazawa, Hitoshi

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