The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness von Kim, Kyumin, Calabrese, Peter, Wang, Shanshan, Qin, Chao, Rao, Youliang, Feng, Pinghui, Chen, Xiaojiang S.

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Insights into the Structures and Multimeric Status of APOBEC Proteins Involved in Viral Restriction and Other Cellular Functions von Chen, Xiaojiang S.

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Crystal structures of APOBEC3G N-domain alone and its complex with DNA von Xiao, Xiao, Li, Shu-Xing, Yang, Hanjing, Chen, Xiaojiang S.

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Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G von Yang, Hanjing, Kim, Kyumin, Li, Shuxing, Pacheco, Josue, Chen, Xiaojiang S.

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Family-Wide Comparative Analysis of Cytidine and Methylcytidine Deamination by Eleven Human APOBEC Proteins von Ito, Fumiaki, Fu, Yang, Kao, Shen-Chi A., Yang, Hanjing, Chen, Xiaojiang S.

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DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B von Fu, Yang, Ito, Fumiaki, Zhang, Gewen, Fernandez, Braulio, Yang, Hanjing, Chen, Xiaojiang S

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Promoter-independent synthesis of chemically modified RNA by human DNA polymerase θ variants von Tredinnick, Taylor, Kent, Tatiana, Minakhin, Leonid, Li, Ziyuan, Madzo, Jozef, Chen, Xiaojiang S, Pomerantz, Richard T

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Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain von Yang, Hanjing, Pacheco, Josue, Kim, Kyumin, Bokani, Ayub, Ito, Fumiaki, Ebrahimi, Diako, Chen, Xiaojiang S.

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SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response von Liu, Yongzhen, Qin, Chao, Rao, Youliang, Ngo, Chau, Feng, Joshua J., Zhao, Jun, Zhang, Shu, Wang, Ting-Yu, Carriere, Jessica, Savas, Ali Can, Zarinfar, Mehrnaz, Rice, Stephanie, Yang, Hanging, Yuan, Weiming, Camarero, Julio A., Yu, Jianhua, Chen, Xiaojiang S., Zhang, Chao, Feng, Pinghui

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Multiple Heparan Sulfate Binding Site Engagements Are Required for the Infectious Entry of Human Papillomavirus Type 16 von Richards, Kathleen F, Bienkowska-Haba, Malgorzata, Dasgupta, Jhimli, Chen, Xiaojiang S, Sapp, Martin

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Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H von Ito, Fumiaki, Alvarez-Cabrera, Ana L., Kim, Kyumin, Zhou, Z. Hong, Chen, Xiaojiang S.

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Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation von Xiao, Xiao, Yang, Hanjing, Arutiunian, Vagan, Fang, Yao, Besse, Guillaume, Morimoto, Cherie, Zirkle, Brett, Chen, Xiaojiang S

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Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G von Yang, Hanjing, Ito, Fumiaki, Wolfe, Aaron D., Li, Shuxing, Mohammadzadeh, Nazanin, Love, Robin P., Yan, Maocai, Zirkle, Brett, Gaba, Amit, Chelico, Linda, Chen, Xiaojiang S.

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Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes von Sanchez, Ambrocio, Ortega, Pedro, Sakhtemani, Ramin, Manjunath, Lavanya, Oh, Sunwoo, Bournique, Elodie, Becker, Alexandrea, Kim, Kyumin, Durfee, Cameron, Temiz, Nuri Alpay, Chen, Xiaojiang S., Harris, Reuben S., Lawrence, Michael S., Buisson, Rémi

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Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM von Ito, Fumiaki, Li, Ziyuan, Minakhin, Leonid, Chandramouly, Gurushankar, Tyagi, Mrityunjay, Betsch, Robert, Krais, John J., Taberi, Bernadette, Vekariya, Umeshkumar, Calbert, Marissa, Skorski, Tomasz, Johnson, Neil, Chen, Xiaojiang S., Pomerantz, Richard T.

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Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase von Quan, Yun, Xia, Yisui, Liu, Lu, Cui, Jiamin, Li, Zhen, Cao, Qinhong, Chen, Xiaojiang S., Campbell, Judith L., Lou, Huiqiang

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Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors von Fried, William, Tyagi, Mrityunjay, Minakhin, Leonid, Chandramouly, Gurushankar, Tredinnick, Taylor, Ramanjulu, Mercy, Auerbacher, William, Calbert, Marissa, Rusanov, Timur, Hoang, Trung, Borisonnik, Nikita, Betsch, Robert, Krais, John J., Wang, Yifan, Vekariya, Umeshkumar M., Gordon, John, Morton, George, Kent, Tatiana, Skorski, Tomasz, Johnson, Neil, Childers, Wayne, Chen, Xiaojiang S., Pomerantz, Richard T.

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A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization von Wang, Wenbo, Nie, Jianhui, Prochnow, Courtney, Truong, Carolyn, Jia, Zheng, Wang, Suting, Chen, Xiaojiang S, Wang, Youchun

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The in vitro Biochemical Characterization of an HIV-1 Restriction Factor APOBEC3F: Importance of Loop 7 on Both CD1 and CD2 for DNA Binding and Deamination von Chen, Qihan, Xiao, Xiao, Wolfe, Aaron, Chen, Xiaojiang S.

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Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications von Chen, Xiaojiang S, Holden, Lauren G, Prochnow, Courtney, Chang, Y. Paul, Bransteitter, Ronda, Chelico, Linda, Sen, Udayaditya, Stevens, Raymond C, Goodman, Myron F

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