Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation von Zhang, Qi, Tang, Weichun, Stancanelli, Eduardo, Jung, Eunkyung, Syed, Zulfeqhar, Pagadala, Vijayakanth, Saidi, Layla, Chen, Catherine Z., Gao, Peng, Xu, Miao, Pavlinov, Ivan, Li, Bing, Huang, Wenwei, Chen, Liqiang, Liu, Jian, Xie, Hang, Zheng, Wei, Ye, Yihong

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Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics von Zhu, Hu, Chen, Catherine Z., Sakamuru, Srilatha, Zhao, Jinghua, Ngan, Deborah K., Simeonov, Anton, Hall, Mathew D., Xia, Menghang, Zheng, Wei, Huang, Ruili

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Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs von Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo

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A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike von Fu, Ying, da Fonseca Rezende E Mello, Juliana, Fleming, Bryan D, Renn, Alex, Chen, Catherine Z, Hu, Xin, Xu, Miao, Gorshkov, Kirill, Hanson, Quinlin, Zheng, Wei, Lee, Emily M, Perera, Lalith, Petrovich, Robert, Pradhan, Manisha, Eastman, Richard T, Itkin, Zina, Stanley, Thomas B, Hsu, Allen, Dandey, Venkata, Sharma, Kedar, Gillette, William, Taylor, Troy, Ramakrishnan, Nitya, Perkins, Shelley, Esposito, Dominic, Oh, Eunkeu, Susumu, Kimihiro, Wolak, Mason, Ferrer, Marc, Hall, Matthew D, Borgnia, Mario J, Simeonov, Anton

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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules von Childs-Disney, Jessica L., Stepniak-Konieczna, Ewa, Tran, Tuan, Yildirim, Ilyas, Park, HaJeung, Chen, Catherine Z., Hoskins, Jason, Southall, Noel, Marugan, Juan J., Patnaik, Samarjit, Zheng, Wei, Austin, Chris P., Schatz, George C., Sobczak, Krzysztof, Thornton, Charles A., Disney, Matthew D.

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Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1) von Diepenhorst, Natalie A., Petrie, Emma J., Chen, Catherine Z., Wang, Amy, Hossain, Mohammed Akhter, Bathgate, Ross A.D., Gooley, Paul R.

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Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1 von Xiao, Jingbo, Huang, Zaohua, Chen, Catherine Z., Agoulnik, Irina U., Southall, Noel, Hu, Xin, Jones, Raisa E., Ferrer, Marc, Zheng, Wei, Agoulnik, Alexander I., Marugan, Juan J.

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Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1... von Brooks, Brianna M., Pradhan, Manisha, Cheng, Yu-Shan, Gorshkov, Kirill, Farkhondeh, Atena, Chen, Catherine Z., Beers, Jeanette, Liu, Chengyu, Baumgaertel, Karsten, Rodems, Steven, Zheng, Wei

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Elp1p, the Yeast Homolog of the FD Disease Syndrome Protein, Negatively Regulates Exocytosis Independently of Transcriptional Elongation von Rahl, Peter B., Chen, Catherine Z., Collins, Ruth N.

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RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery von Zhu, Wei, Chen, Catherine Z., Gorshkov, Kirill, Xu, Miao, Lo, Donald C., Zheng, Wei

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A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry von Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Shen, Min, Guo, Hui, Zhu, Wei, Klumpp-Thomas, Carleen, Michael, Sam, Itkin, Misha, Itkin, Zina, Straus, Marco R., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R., Chen, Catherine Z.

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Efficient Identification of Anti-SARS-CoV‑2 Compounds Using Chemical Structure- and Biological Activity-Based Modeling von Xu, Tuan, Xu, Miao, Zhu, Wei, Chen, Catherine Z, Zhang, Qi, Zheng, Wei, Huang, Ruili

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High-Throughput Giardia lamblia Viability Assay Using Bioluminescent ATP Content Measurements von CHEN, Catherine Z, KULAKOVA, Liudmila, SOUTHALL, Noel, MARUGAN, Juan J, GALKIN, Andrey, AUSTIN, Christopher P, HERZBERG, Osnat, WEI ZHENG

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Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 von Bobrowski, Tesia, Chen, Lu, Eastman, Richard T., Itkin, Zina, Shinn, Paul, Chen, Catherine Z., Guo, Hui, Zheng, Wei, Michael, Sam, Simeonov, Anton, Hall, Matthew D., Zakharov, Alexey V., Muratov, Eugene N.

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Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV‑2 Cell-Entry Inhibitors von Gao, Peng, Xu, Miao, Zhang, Qi, Chen, Catherine Z, Guo, Hui, Ye, Yihong, Zheng, Wei, Shen, Min

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Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay von Sun, Hongmao, Wang, Yuhong, Chen, Catherine Z., Xu, Miao, Guo, Hui, Itkin, Misha, Zheng, Wei, Shen, Min

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Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening von Gao, Peng, Tambe, Mitali, Chen, Catherine Z., Huang, Wenwei, Tawa, Gregory J., Hirschhorn, Tal, Stockwell, Brent R., Zheng, Wei, Shen, Min

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Biological activity-based modeling identifies antiviral leads against SARS-CoV-2 von Huang, Ruili, Xu, Miao, Zhu, Hu, Chen, Catherine Z., Zhu, Wei, Lee, Emily M., He, Shihua, Zhang, Li, Zhao, Jinghua, Shamim, Khalida, Bougie, Danielle, Huang, Wenwei, Xia, Menghang, Hall, Mathew D., Lo, Donald, Simeonov, Anton, Austin, Christopher P., Qiu, Xiangguo, Tang, Hengli, Zheng, Wei

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Identification of Small-Molecule Agonists of Human Relaxin Family Receptor 1 (RXFP1) by Using a Homogenous Cell-Based cAMP Assay von Chen, Catherine Z., Southall, Noel, Xiao, Jingbo, Marugan, Juan J., Ferrer, Marc, Hu, Xin, Jones, Raisa E., Feng, Shu, Agoulnik, Irina U., Zheng, Wei, Agoulnik, Alexander I.

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Dual prenylation is required for Rab protein localization and function von Calero, Monica, Chen, Catherine Z, Zhu, Wenyan, Winand, Nena, Havas, Karyn A, Gilbert, Penny M, Burd, Christopher G, Collins, Ruth N

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