The utility of animal models to evaluate novel anti‐obesity agents von Vickers, Steven P, Jackson, Helen C, Cheetham, Sharon C

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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility von Byers, Spencer, Buchler, Ingrid P., DePasquale, Michael, Rowley, Helen L., Kulkarni, Rajiv S., Pinder, Lucy, Kolobova, Anna, Li, Cailian, Au, Vinh, Akuma, Daniel, Zhang, Gongliang, Wei, Huijun, Cheetham, Sharon C., Barrow, James C., Carr, Gregory V.

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Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model von Fromont, Christophe, Atzori, Alessio, Kaur, Divneet, Hashmi, Lubna, Greco, Graziella, Cabanillas, Alejandro, Nguyen, Huy Van, Jones, D. Heulyn, Garzón, Miguel, Varela, Ana, Stevenson, Brett, Iacobini, Greg P, Lenoir, Marc, Rajesh, Sundaresan, Box, Clare, Kumar, Jitendra, Grant, Paige, Novitskaya, Vera, Morgan, Juliet, Sorrell, Fiona J, Redondo, Clara, Kramer, Andreas, Harris, C. John, Leighton, Brendan, Vickers, Steven P, Cheetham, Sharon C, Kenyon, Colin, Grabowska, Anna M, Overduin, Michael, Berditchevski, Fedor, Weston, Chris J, Knapp, Stefan, Fischer, Peter M, Butterworth, Sam

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Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese r... von Vickers, Steven P, Cheetham, Sharon C, Headland, Katie R, Dickinson, Keith, Grempler, Rolf, Mayoux, Eric, Mark, Michael, Klein, Thomas

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Receptor Occupancy and Brain Free Fraction von Watson, Jeanette, Wright, Sara, Lucas, Adam, Clarke, Kirsten L., Viggers, Jean, Cheetham, Sharon, Jeffrey, Phil, Porter, Rod, Read, Kevin D.

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Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments von Chapman, Victoria, Vickers, Steven, Cheetham, Sharon, Byrne, Frederika Maria

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Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats von Jones, Robert B., Vickers, Steven P., Cheetham, Sharon C., Headland, Katie R., Mark, Michael, Klein, Thomas

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Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats von Izzi-Engbeaya, Chioma, Ma, Yue, Buckley, Niki W., Ratnasabapathy, Risheka, Richardson, Errol, Counsell, John R., Fernandes-Freitas, Isabel, Norton, Mariana, Farooq, Gala, Mirza, Zainab, Cai, Mingzhu, Cheetham, Sharon, Seckl, Jonathan, Murphy, Kevin, Dhillo, Waljit S., Gardiner, James

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Prokineticin 2 Is a Hypothalamic Neuropeptide That Potently Inhibits Food Intake von GARDINER, James V, BATAVELJIC, Attia, EBLING, Francis J. P, VICKERS, Steven P, CHEETHAM, Sharon, GHATEI, Mohammad A, BLOOM, Stephen R, DHILLO, Waljit S, PATEL, Neekhil A, BEWICK, Gavin A, ROY, Debabrata, CAMPBELL, Daniel, GREENWOOD, Hannah C, MURPHY, Kevin G, HAMEED, Saira, JETHWA, Preeti H

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FRI-304-Elafibranor and pioglitazone reduce NASH and fibrosis in a genetically-obese dietary-induced NASH mouse model von Headland, Katie R., Dickinson, Katie, Cheetham, Sharon

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Dexamethasone and Enalaprilat but Not SB525334 Exhibit Anti-Inflammatory Properties in Precision-Cut Kidney Slices (PCKSs) Obtained from Mice with Adriamycin-Induced Nephropathy: S... von Pijacka, Wioletta, Lincevicius, Gisele, Willis, Jessica, Levers, Connor T., Butler, Stephanie, Vickers, Steven, Cheetham, Sharon

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Ex vivo receptor binding in rats as a rapid screen for CNS penetration and occupancy of abuse-related molecular targets von Jagger, Liz, Heal, David J., Cheetham, Sharon C.

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Comparison of the physical dependence syndromes produced in rats by morphine and diazepam von Heal, David, Goddard, Simon, Smith, Sharon, Cheetham, Sharon

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Histologic Characterization of Retina Neuroglia Modifications in Diabetic Zucker Diabetic Fatty Rats von Fernandez-Bueno, Ivan, Jones, Robert, Soriano-Romaní, Laura, López-García, Antonio, Galvin, Orla, Cheetham, Sharon, Diebold, Yolanda

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GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin von Holst, Birgitte, Egerod, Kristoffer L, Schild, Enrico, Vickers, Steve P, Cheetham, Sharon, Gerlach, Lars-Ole, Storjohann, Laura, Stidsen, Carsten E, Jones, Rob, Beck-Sickinger, Annette G, Schwartz, Thue W

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Reduced dopamine turnover in the basal ganglia of depressed suicides von Bowden, Christine, Cheetham, Sharon C, Lowther, Sandra, Katona, Cornelius L.E, Crompton, M.Rufus, Horton, Roger W

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The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates von Hansard, Matthew J., Smith, Lance A., Jackson, Michael J., Cheetham, Sharon C., Jenner, Peter

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Dopamine and [mu]-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder von Heal, David J, Hallam, Michelle, Prow, Michael, Gosden, Jane, Cheetham, Sharon, Choi, Yong K, Tarazi, Frank, Hutson, Peter

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Dopamine reuptake inhibition and failure to evoke dyskinesia in MPTP-treated primates von Hansard, Matthew J, Smith, Lance A, Jackson, Michael J, Cheetham, Sharon C, Jenner, Peter

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MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3 von Cox, Alan, Donnelly, Dan, Kaur, Manminder, Cheetham, Sharon C., Cockcroft, Victor B., Findlay, John B.C.

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