IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction—a retrospective propensity score analysis von Kattih, Badder, Shirvani, Amir, Klement, Piroska, Garrido, Abel Martin, Gabdoulline, Razif, Liebich, Alessandro, Brandes, Maximilian, Chaturvedi, Anuhar, Seeger, Timon, Thol, Felicitas, Göhring, Gudrun, Schlegelberger, Brigitte, Geffers, Robert, John, David, Bavendiek, Udo, Bauersachs, Johann, Ganser, Arnold, Heineke, Joerg, Heuser, Michael

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Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications von Thol, Felicitas, Bollin, Robin, Gehlhaar, Marten, Walter, Carolin, Dugas, Martin, Suchanek, Karl Josef, Kirchner, Aylin, Huang, Liu, Chaturvedi, Anuhar, Wichmann, Martin, Wiehlmann, Lutz, Shahswar, Rabia, Damm, Frederik, Göhring, Gudrun, Schlegelberger, Brigitte, Schlenk, Richard, Döhner, Konstanze, Döhner, Hartmut, Krauter, Jürgen, Ganser, Arnold, Heuser, Michael

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Compassionate use of sorafenib in FLT3-ITD–positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation von Metzelder, Stephan, Wang, Ying, Wollmer, Ellen, Wanzel, Michael, Teichler, Sabine, Chaturvedi, Anuhar, Eilers, Martin, Enghofer, Erich, Neubauer, Andreas, Burchert, Andreas

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Prognostic Significance of ASXL1 Mutations in Patients With Myelodysplastic Syndromes von THOL, Felicitas, FRIESEN, Inna, GÖHRING, Gudrun, SCHUMANN, Christiane, BUG, Gesine, OTTMANN, Oliver, HOFMANN, Wolf-Karsten, SCHLEGELBERGER, Brigitte, HEUSER, Michael, GANSER, Arnold, DAMM, Frederik, YUN, Haiyang, WEISSINGER, Eva M, KRAUTER, Jürgen, WAGNER, Katharina, CHATURVEDI, Anuhar, SHARMA, Amit, WICHMANN, Martin

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A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation von Yang, Min, Pan, Zengkai, Huang, Kezhi, Büsche, Guntram, Liu, Hongyun, Göhring, Gudrun, Rumpel, Regina, Dittrich-Breiholz, Oliver, Talbot, Steven, Scherr, Michaela, Chaturvedi, Anuhar, Eder, Matthias, Skokowa, Julia, Zhou, Jianfeng, Welte, Karl, von Neuhoff, Nils, Liu, Ligen, Ganser, Arnold, Li, Zhixiong

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Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia von Chaturvedi, Anuhar, Gupta, Charu, Gabdoulline, Razif, Borchert, Nora M, Goparaju, Ramya, Kaulfuss, Stefan, Görlich, Kerstin, Schottmann, Renate, Othman, Basem, Welzenbach, Julia, Panknin, Olaf, Wagner, Markus, Geffers, Robert, Ganser, Arnold, Thol, Felicitas, Jeffers, Michael, Haegebarth, Andrea, Heuser, Michael

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Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis von Menon, Manoj B, Sawada, Akihiro, Chaturvedi, Anuhar, Mishra, Pooja, Schuster-Gossler, Karin, Galla, Melanie, Schambach, Axel, Gossler, Achim, Förster, Reinhold, Heuser, Michael, Kotlyarov, Alexey, Kinoshita, Makoto, Gaestel, Matthias

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In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site von Chaturvedi, Anuhar, Goparaju, Ramya, Gupta, Charu, Weder, Julia, Klünemann, Thomas, Araujo Cruz, Michelle Maria, Kloos, Arnold, Goerlich, Kerstin, Schottmann, Renate, Othman, Basem, Struys, Eduard A., Bähre, Heike, Grote-Koska, Denis, Brand, Korbinian, Ganser, Arnold, Preller, Matthias, Heuser, Michael

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Combination treatment of an IDH1 inhibitor with chemotherapy in IDH1 mutant acute myeloid leukemia von Gupta, Charu, Kaulfuss, Stefan, Görlich, Kerstin, Othman, Basem, Chaturvedi, Anuhar, Heuser, Michael

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Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators von Qiu, Jinsong, Zhou, Bing, Thol, Felicitas, Zhou, Yu, Chen, Liang, Shao, Changwei, DeBoever, Christopher, Hou, Jiayi, Li, Hairi, Chaturvedi, Anuhar, Ganser, Arnold, Bejar, Rafael, Zhang, Dong-Er, Fu, Xiang-Dong, Heuser, Michael

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Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody von Bähr-Mahmud, Hayat, Ellinghaus, Ursula, Stadler, Christiane R., Fischer, Leyla, Lindemann, Claudia, Chaturvedi, Anuhar, Diekmann, Jan, Wöll, Stefan, Biermann, Imke, Hebich, Bernhard, Scharf, Caroline, Siefke, Manuela, Roth, Alexandra S., Rao, Martin, Brettschneider, Kerstin, Ewen, Eva-Maria, Şahin, Uğur, Türeci, Özlem

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Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex von Heuser, Michael, Yun, Haiyang, Berg, Tobias, Yung, Eric, Argiropoulos, Bob, Kuchenbauer, Florian, Park, Gyeongsin, Hamwi, Iyas, Palmqvist, Lars, Lai, Courteney K., Leung, Malina, Lin, Grace, Chaturvedi, Anuhar, Thakur, Basant Kumar, Iwasaki, Masayuki, Bilenky, Mikhail, Thiessen, Nina, Robertson, Gordon, Hirst, Martin, Kent, David, Wilson, Nicola K., Göttgens, Bertie, Eaves, Connie, Cleary, Michael L., Marra, Marco, Ganser, Arnold, Humphries, R. Keith

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Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML) von Scherr, Michaela, Chaturvedi, Anuhar, Battmer, Karin, Dallmann, Iris, Schultheis, Beate, Ganser, Arnold, Eder, Matthias

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Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite von Berger, Raffaela S, Wachsmuth, Christian J, Waldhier, Magdalena C, Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar, Niller, Hans-Helmut, Bumes, Elisabeth, Hau, Peter, Proescholdt, Martin, Gronwald, Wolfram, Heuser, Michael, Kreutz, Marina, Oefner, Peter J, Dettmer, Katja

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Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia von Yun, Haiyang, Damm, Frederik, Yap, Damian, Schwarzer, Adrian, Chaturvedi, Anuhar, Jyotsana, Nidhi, Lübbert, Michael, Bullinger, Lars, Döhner, Konstanze, Geffers, Robert, Aparicio, Samuel, Humphries, R Keith, Ganser, Arnold, Heuser, Michael

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Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo von Jyotsana, Nidhi, Sharma, Amit, Chaturvedi, Anuhar, Budida, Ramachandramouli, Scherr, Michaela, Kuchenbauer, Florian, Lindner, Robert, Noyan, Fatih, Sühs, Kurt-Wolfram, Stangel, Martin, Grote-Koska, Denis, Brand, Korbinian, Vornlocher, Hans-Peter, Eder, Matthias, Thol, Felicitas, Ganser, Arnold, Humphries, R. Keith, Ramsay, Euan, Cullis, Pieter, Heuser, Michael

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Prognostic Importance of Histone Methyltransferase MLL5 Expression in Acute Myeloid Leukemia von Damm, Frederik, Oberacker, Tina, Thol, Felicitas, Surdziel, Ewa, Wagner, Katharina, Chaturvedi, Anuhar, Morgan, Michael, Bomm, Karoline, Göhring, Gudrun, Lübbert, Michael, Kanz, Lothar, Fiedler, Walter, Schlegelberger, Brigitte, Heil, Gerhard, Schlenk, Richard F, Döhner, Konstanze, Döhner, Hartmut, Krauter, Jürgen, Ganser, Arnold, Heuser, Michael

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Clinical and functional implications of microRNA mutations in a cohort of 935 patients with myelodysplastic syndromes and acute myeloid leukemia von Thol, Felicitas, Scherr, Michaela, Kirchner, Aylin, Shahswar, Rabia, Battmer, Karin, Kade, Sofia, Chaturvedi, Anuhar, Koenecke, Christian, Stadler, Michael, Platzbecker, Uwe, Thiede, Christian, Schroeder, Thomas, Kobbe, Guido, Bug, Gesine, Ottmann, Oliver, Hofmann, Wolf-Karsten, Kröger, Nicolaus, Fiedler, Walter, Schlenk, Richard, Döhner, Konstanze, Döhner, Hartmut, Krauter, Jürgen, Eder, Matthias, Ganser, Arnold, Heuser, Michael

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A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2 von Arora, Sahil, Joshi, Gaurav, Chaturvedi, Anuhar, Heuser, Michael, Patil, Santoshkumar, Kumar, Raj

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Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation von Kröger, Nicolaus, Panagiota, Victoria, Badbaran, Anita, Zabelina, Tatjana, Triviai, Ioanna, Araujo Cruz, Michelle Maria, Shahswar, Rabia, Ayuk, Francis, Gehlhaar, Marten, Wolschke, Christine, Bollin, Robin, Walter, Carolin, Dugas, Martin, Wiehlmann, Lutz, Lehmann, Ulrich, Koenecke, Christian, Chaturvedi, Anuhar, Alchalby, Haefaa, Stadler, Michael, Eder, Matthias, Christopeit, Max, Göhring, Gudrun, Koenigsmann, Michael, Schlegelberger, Brigitte, Kreipe, Hans-Heinrich, Ganser, Arnold, Stocking, Carol, Fehse, Boris, Thol, Felicitas, Heuser, Michael

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