Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension von Plaunt, Adam J, Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R, Chapman, Richard W, Li, Zhili, Cipolla, David C, Perkins, Walter R, Malinin, Vladimir S

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Therapeutic administration of inhaled INS1009, a treprostinil prodrug formulation, inhibits bleomycin-induced pulmonary fibrosis in rats von Corboz, Michel R., Zhang, Jimin, LaSala, Daniel, DiPetrillo, Keith, Li, Zhili, Malinin, Vladimir, Brower, Jeremy, Kuehl, Philip J., Barrett, Ted E., Perkins, Walter R., Chapman, Richard W.

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New IL-17 Family Members Promote Th1 or Th2 Responses in the Lung: In Vivo Function of the Novel Cytokine IL-25 von Hurst, Stephen D, Muchamuel, Tony, Gorman, Daniel M, Gilbert, Jonathan M, Clifford, Theresa, Kwan, Sylvia, Menon, Satish, Seymour, Brian, Jackson, Craig, Kung, Ted T, Brieland, Joan K, Zurawski, Sandra M, Chapman, Richard W, Zurawski, Gerard, Coffman, Robert L

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Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil von Chapman, Richard W, Corboz, Michel R, Fernandez, Carlos, Sullivan, Eugene, Stautberg, Andy, Plaunt, Adam J, Konicek, Donna M, Malinin, Vladimir, Li, Zhili, Cipolla, David, Perkins, Walter

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Th2 cytokines and asthma. The role of interleukin-5 in allergic eosinophilic disease von Greenfeder, S, Umland, S P, Cuss, F M, Chapman, R W, Egan, R W

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Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension von Corboz, Michel R., Plaunt, Adam J., Malinin, Vladimir S., Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R., Chapman, Richard W.

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Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension von Corboz, Michel R., Plaunt, Adam J., Malinin, Vladimir, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R., Chapman, Richard W.

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An overview of the biology of a long-acting inhaled treprostinil prodrug von Chapman, Richard W., Corboz, Michel R., Malinin, Vladimir S., Plaunt, Adam J., Konicek, Donna M., Li, Zhili, Perkins, Walter R.

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Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human l... von Corboz, Michel R., Salvail, William, Gagnon, Sandra, LaSala, Daniel, Laurent, Charles E., Salvail, Dany, Chen, Kuan-Ju, Cipolla, David, Perkins, Walter R., Chapman, Richard W.

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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug von Corboz, Michel R., Li, Zhili, Malinin, Vladimir, Plaunt, Adam J., Konicek, Donna M., Leifer, Franziska G., Chen, Kuan-Ju, Laurent, Charles E., Yin, Han, Biernat, Marzena C., Salvail, Dany, Zhuang, Jianguo, Xu, Fadi, Curran, Aidan, Perkins, Walter R., Chapman, Richard W.

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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections von Plaunt, Adam J, Rose, Sasha J, Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P, Dorfman, Arielle, Smith, Barrett T, Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G, Corboz, Michel R, Chapman, Richard W, Cipolla, David, Perkins, Walter R, Malinin, Vladimir S, Konicek, Donna M

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Correction for Plaunt et al., “Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcu... von Plaunt, Adam J., Rose, Sasha J., Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P., Dorfman, Arielle, Smith, Barrett T., Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G., Corboz, Michel R., Chapman, Richard W., Cipolla, David, Perkins, Walter R., Malinin, Vladimir S., Konicek, Donna M.

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Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats von Chapman, Richard W., Li, Zhili, Chun, Donald, Gauani, Helena, Malinin, Vladimir, Plaunt, Adam J., Cipolla, David, Perkins, Walter R., Corboz, Michel R.

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Effect of Anti-mIL-9 Antibody on the Development of Pulmonary Inflammation and Airway Hyperresponsiveness in Allergic Mice von Kung, Ted T, Luo, Bin, Crawley, Yvette, Garlisi, Charles G, Devito, Kristine, Minnicozzi, Michael, Egan, Robert W, Kreutner, William, Chapman, Richard W

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Influence of central antitussive drugs on the cough motor pattern von Bolser, Donald C, Hey, John A, Chapman, Richard W

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Canine models of asthma and COPD von Chapman, Richard W

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Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil von Chapman, Richard W., Li, Zhili, Corboz, Michel R., Gauani, Helena, Plaunt, Adam J., Konicek, Donna M., Leifer, Franziska G., Laurent, Charles E., Yin, Han, Salvail, Dany, Dziak, Chad, Perkins, Walter R., Malinin, Vladimir

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Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction von Moy, Lily Y, Jia, Yanlin, Caniga, Michael, Lieber, Gissela, Gil, Malgorzata, Fernandez, Xiomara, Sirkowski, Erich, Miller, Richard, Alexander, Jessica P, Lee, Hyun-Hee, Shin, John D, Ellis, J Michael, Chen, Hongmin, Wilhelm, Alan, Yu, Hongshi, Vincent, Stella, Chapman, Richard W, Kelly, Nancy, Hickey, Emily, Abraham, William M, Northrup, Alan, Miller, Thomas, Houshyar, Hani, Crackower, Michael A

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Pharmacological characterization of the late phase reduction in lung functions and correlations with microvascular leakage and lung edema in allergen-challenged Brown Norway rats von Mauser, Peter J, House, Aileen, Jones, Howard, Correll, Craig, Boyce, Christopher, Chapman, Richard W

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SCH 206272: a potent, orally active tachykinin NK1, NK2, and NK3 receptor antagonist von ANTHES, John C, CHAPMAN, Richard W, RIZZO, Charles, CRAWLEY, Yvette, SHIH, Neng-Yang, PIWINSKI, John, REICHARD, Greg, TING, Pauline, CARRUTHERS, Nick, CUSS, Francis M, BILLAH, Motasim, KREUTNER, William, RICHARD, Christian, EGAN, Robert W, ECKEL, Stephen, CORBOZ, Michel, HEY, John A, FERNANDEZ, Xiomara, GREENFEDER, Scott, MCLEOD, Robbie, SEHRING, Susan

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