Cholesterol sensing, trafficking, and esterification von Chang, Ta-Yuan, Chang, Catherine C Y, Ohgami, Nobutaka, Yamauchi, Yoshio

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Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the p... von Shibuya, Yohei, Niu, Zhaoyang, Bryleva, Elena Y, Harris, Brent T, Murphy, Stephanie R, Kheirollah, Alireza, Bowen, Zachary D, Chang, Catherine C.Y, Chang, Ta-Yuan

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ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD von Bryleva, Elena Y, Rogers, Maximillian A, Chang, Catherine C.Y, Buen, Floyd, Harris, Brent T, Rousselet, Estelle, Seidah, Nabil G, Oddo, Salvatore, LaFerla, Frank M, Spencer, Thomas A, Hickey, William F, Chang, Ta-Yuan

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TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation von Lei, Lei, Xiong, Ying, Chen, Jia, Yang, Jin-Bo, Wang, Yi, Yang, Xin-Ying, Chang, Catherine C.Y., Song, Bao-Liang, Chang, Ta-Yuan, Li, Bo-Liang

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Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance von Shibuya, Yohei, Chang, Catherine C Y, Huang, Li-Hao, Bryleva, Elena Y, Chang, Ta-Yuan

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Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity von Sakashita, Naomi, Chang, Catherine C.Y., Lei, Xiaofeng, Fujiwara, Yukio, Takeya, Motohiro, Chang, Ta-Yuan

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Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions von Melton, Elaina M., Li, Haibo, Benson, Jalen, Sohn, Paul, Huang, Li-Hao, Song, Bao-Liang, Li, Bo-Liang, Chang, Catherine C.Y., Chang, Ta-Yuan

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Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum von Yamauchi, Yoshio, Iwamoto, Noriyuki, Rogers, Maximillian A., Abe-Dohmae, Sumiko, Fujimoto, Toyoshi, Chang, Catherine C.Y., Ishigami, Masato, Kishimoto, Takuma, Kobayashi, Toshihide, Ueda, Kazumitsu, Furukawa, Koichi, Chang, Ta-Yuan, Yokoyama, Shinji

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Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location von Lin, Song, Lu, Xiaohui, Chang, Catherine C Y, Chang, Ta-Yuan

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Plasma Membrane Rafts Complete Cholesterol Synthesis by Participating in Retrograde Movement of Precursor Sterols von Yamauchi, Yoshio, Reid, Patrick C., Sperry, Jeffrey B., Furukawa, Koichi, Takeya, Motohiro, Chang, Catherine C.Y., Chang, Ta-Yuan

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Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression von Huang, Li-Hao, Melton, Elaina M., Li, Haibo, Sohn, Paul, Rogers, Maximillian A., Mulligan-Kehoe, Mary Jo, Fiering, Steven N., Hickey, William F., Chang, Catherine C.Y., Chang, Ta-Yuan

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Roles of Endogenously Synthesized Sterols in the Endocytic Pathway von Sugii, Shigeki, Lin, Song, Ohgami, Nobutaka, Ohashi, Masato, Chang, Catherine C.Y., Chang, Ta-Yuan

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Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex von Urano, Yasuomi, Watanabe, Hiroshi, Murphy, Stephanie R, Shibuya, Yohei, Geng, Yong, Peden, Andrew A, Chang, Catherine C.Y, Chang, Ta Yuan

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Niemann-Pick Type C Disease and Intracellular Cholesterol Trafficking von Chang, Ta-Yuan, Reid, Patrick C., Sugii, Shigeki, Ohgami, Nobutaka, Cruz, Jonathan C., Chang, Catherine C.Y.

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MiR-9 reduces human acyl-coenzyme A：cholesterol acyltransferase-1 to decrease THP-1 macrophage-derived foam cell formation von Xu, Jiajia, Hu, Guangjing, Lu, Ming, Xiong, Ying, Li, Qin, Chang, Catherine C Y, Song, Baoliang, Chang, Tayuan, Li, Boliang

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A simple method to disrupt and restore subunit interaction of acyl-CoA:cholesterol acyltransferase 1 von Neumann, Bryan, Chang, Catherine C.Y., Chang, Ta-Yuan

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The Active Site His-460 of Human Acyl-coenzyme A:Cholesterol Acyltransferase 1 Resides in a Hitherto Undisclosed Transmembrane Domain von Guo, Zhan-Yun, Lin, Song, Heinen, Jennifer A., Chang, Catherine C.Y., Chang, Ta-Yuan

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Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2 von Chang, T Y, Chang, C C, Lin, S, Yu, C, Li, B L, Miyazaki, A

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Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine von Chang, C C, Sakashita, N, Ornvold, K, Lee, O, Chang, E T, Dong, R, Lin, S, Lee, C Y, Strom, S C, Kashyap, R, Fung, J J, Farese, Jr, R V, Patoiseau, J F, Delhon, A, Chang, T Y

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Intracellular cholesterol mobilization involved in the ABCA1/apolipoprotein-mediated assembly of high density lipoprotein in fibroblasts von Yamauchi, Yoshio, Chang, Catherine C.Y., Hayashi, Michi, Abe-Dohmae, Sumiko, Reid, Patrick C., Chang, Ta-Yuan, Yokoyama, Shinji

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