DNA TOPOISOMERASES: Structure, Function, and Mechanism von Champoux, James J

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Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1 von Interthal, Heidrun, Champoux, James J

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The Tyrosyl-DNA Phosphodiesterase Tdp1 is a Member of the Phospholipase D Superfamily von Interthal, Heidrun, Pouliot, Jeffrey J., Champoux, James J.

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Human Tdp1 Cleaves a Broad Spectrum of Substrates, Including Phosphoamide Linkages von Interthal, Heidrun, Chen, Hong Jing, Champoux, James J.

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A Model for the Mechanism of Human Topoisomerase I von Stewart, Lance, Redinbo, Matthew R., Qui, Xiayang, Wim G. J. Hol, Champoux, James J.

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RNase H activity: Structure, specificity, and function in reverse transcription von Schultz, Sharon J., Champoux, James J.

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Human DNA topoisomerase I: relaxation, roles, and damage control von Leppard, John B, Champoux, James J

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Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA von Redinbo, Matthew R., Stewart, Lance, Kuhn, Peter, Champoux, James J., Wim G. J. Hol

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Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription von Champoux, James J, Schultz, Sharon J

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SCAN1 mutant Tdp1 accumulates the enzyme-DNA intermediate and causes camptothecin hypersensitivity von Interthal, Heidrun, Chen, Hong Jing, Kehl-Fie, Thomas E, Zotzmann, Jörg, Leppard, John B, Champoux, James J

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The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA von Davies, Douglas R., Mushtaq, Adeel, Interthal, Heidrun, Champoux, James J., Hol, Wim G.J.

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The Crystal Structure of Human Tyrosyl-DNA Phosphodiesterase, Tdp1 von Davies, Douglas R, Interthal, Heidrun, Champoux, James J, Hol, Wim G.J

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Pausing during Reverse Transcription Increases the Rate of Retroviral Recombination von LANCIAULT, Christian, CHAMPOUX, James J

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Insights into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate and Tungstate-inhibited Structures von Davies, Douglas R., Interthal, Heidrun, Champoux, James J., Hol, Wim G.J.

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Sequence, Distance, and Accessibility Are Determinants of 5′-End-directed Cleavages by Retroviral RNases H von Schultz, Sharon J., Zhang, Miaohua, Champoux, James J.

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Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA von Redinbo, Matthew R, Champoux, James J, Hol, Wim G. J

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Structure-Based Analysis of the Effects of Camptothecin on the Activities of Human Topoisomerase I von CHAMPOUX, JAMES J.

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Preferred Sequences within a Defined Cleavage Window Specify DNA 3′ End-directed Cleavages by Retroviral RNases H von Schultz, Sharon J., Zhang, Miaohua, Champoux, James J.

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The Role of Lysine 532 in the Catalytic Mechanism of Human Topoisomerase I von Interthal, Heidrun, Quigley, Paulene M., Hol, Wim G.J., Champoux, James J.

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DNA topoisomerase I is involved in both repression and activation of transcription von Merino, Alejandro, Madden, Knut R, Lane, William S, Champoux, James J, Reinberg, Danny

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