Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance von Romani, Patrizia, Nirchio, Nunzia, Arboit, Mattia, Barbieri, Vito, Tosi, Anna, Michielin, Federica, Shibuya, Soichi, Benoist, Thomas, Wu, Danchen, Hindmarch, Charles Colin Thomas, Giomo, Monica, Urciuolo, Anna, Giamogante, Flavia, Roveri, Antonella, Chakravarty, Probir, Montagner, Marco, Calì, Tito, Elvassore, Nicola, Archer, Stephen L., De Coppi, Paolo, Rosato, Antonio, Martello, Graziano, Dupont, Sirio

Volltext

A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases von Montfort, Anne, Pearce, Oliver, Maniati, Eleni, Vincent, Benjamin G, Bixby, Lisa, Böhm, Steffen, Dowe, Thomas, Wilkes, Edmund H, Chakravarty, Probir, Thompson, Richard, Topping, Joanne, Cutillas, Pedro R, Lockley, Michelle, Serody, Jonathan S, Capasso, Melania, Balkwill, Frances R

Volltext

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells von Omenetti, Sara, Bussi, Claudio, Metidji, Amina, Iseppon, Andrea, Lee, Sunjae, Tolaini, Mauro, Li, Ying, Kelly, Gavin, Chakravarty, Probir, Shoaie, Saeed, Gutierrez, Maximiliano G., Stockinger, Brigitta

Volltext

TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition von Ramachandran, Anassuya, Vizán, Pedro, Das, Debipriya, Chakravarty, Probir, Vogt, Janis, Rogers, Katherine W, Müller, Patrick, Hinck, Andrew P, Sapkota, Gopal P, Hill, Caroline S

Volltext

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis von Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne

Volltext

ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells von Vaidyanathan, Aparajitha, Sawers, Lynne, Gannon, Anne-Louise, Chakravarty, Probir, Scott, Alison L, Bray, Susan E, Ferguson, Michelle J, Smith, Gillian

Volltext

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia von Passaro, Diana, Di Tullio, Alessandro, Abarrategi, Ander, Rouault-Pierre, Kevin, Foster, Katie, Ariza-McNaughton, Linda, Montaner, Beatriz, Chakravarty, Probir, Bhaw, Leena, Diana, Giovanni, Lassailly, François, Gribben, John, Bonnet, Dominique

Volltext

An isoform of Dicer protects mammalian stem cells against multiple RNA viruses von Poirier, Enzo Z, Buck, Michael D, Chakravarty, Probir, Carvalho, Joana, Frederico, Bruno, Cardoso, Ana, Healy, Lyn, Ulferts, Rachel, Beale, Rupert, Reis e Sousa, Caetano

Volltext

Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells von Shah, Kathleen, Maradana, Muralidhara Rao, Joaquina Delàs, M., Metidji, Amina, Graelmann, Frederike, Llorian, Miriam, Chakravarty, Probir, Li, Ying, Tolaini, Mauro, Shapiro, Michael, Kelly, Gavin, Cheshire, Chris, Bhurta, Deendyal, Bharate, Sandip B., Stockinger, Brigitta

Volltext

Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast von Navarro, Francisco J, Chakravarty, Probir, Nurse, Paul

Volltext

Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination von Montagner, Marco, Bhome, Rahul, Hooper, Steven, Chakravarty, Probir, Qin, Xiao, Sufi, Jahangir, Bhargava, Ajay, Ratcliffe, Colin D. H., Naito, Yutaka, Pocaterra, Arianna, Tape, Christopher J., Sahai, Erik

Volltext

Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity von Giampazolias, Evangelos, Schulz, Oliver, Lim, Kok Haw Jonathan, Rogers, Neil C., Chakravarty, Probir, Srinivasan, Naren, Gordon, Oliver, Cardoso, Ana, Buck, Michael D., Poirier, Enzo Z., Canton, Johnathan, Zelenay, Santiago, Sammicheli, Stefano, Moncaut, Natalia, Varsani-Brown, Sunita, Rosewell, Ian, Reis e Sousa, Caetano

Volltext

Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization von del Pozo Martin, Yaiza, Park, Danielle, Ramachandran, Anassuya, Ombrato, Luigi, Calvo, Fernando, Chakravarty, Probir, Spencer-Dene, Bradley, Derzsi, Stefanie, Hill, Caroline S., Sahai, Erik, Malanchi, Ilaria

Volltext

Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers von Pearce, Oliver M T, Delaine-Smith, Robin M, Maniati, Eleni, Nichols, Sam, Wang, Jun, Böhm, Steffen, Rajeeve, Vinothini, Ullah, Dayem, Chakravarty, Probir, Jones, Roanne R, Montfort, Anne, Dowe, Tom, Gribben, John, Jones, J Louise, Kocher, Hemant M, Serody, Jonathan S, Vincent, Benjamin G, Connelly, John, Brenton, James D, Chelala, Claude, Cutillas, Pedro R, Lockley, Michelle, Bessant, Conrad, Knight, Martin M, Balkwill, Frances R

Volltext

Equivocal, explicit and emergent actions of PKC isoforms in cancer von Parker, Peter J., Brown, Sophie J., Calleja, Veronique, Chakravarty, Probir, Cobbaut, Mathias, Linch, Mark, Marshall, Jacqueline J. T., Martini, Silvia, McDonald, Neil Q., Soliman, Tanya, Watson, Lisa

Volltext

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses von Blagih, Julianna, Zani, Fabio, Chakravarty, Probir, Hennequart, Marc, Pilley, Steven, Hobor, Sebastijan, Hock, Andreas K., Walton, Josephine B., Morton, Jennifer P., Gronroos, Eva, Mason, Susan, Yang, Ming, McNeish, Iain, Swanton, Charles, Blyth, Karen, Vousden, Karen H.

Volltext

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130 von Joachim, Justin, Jefferies, Harold B.J., Razi, Minoo, Frith, David, Snijders, Ambrosius P., Chakravarty, Probir, Judith, Delphine, Tooze, Sharon A.

Volltext

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity von Torres, Cristina Morales, Biran, Alva, Burney, Matthew J., Patel, Harshil, Henser-Brownhill, Tristan, Cohen, Ayelet-Hashahar Shapira, Li, Yilong, Ben-Hamo, Rotem, Nye, Emma, Spencer-Dene, Bradley, Chakravarty, Probir, Efroni, Sol, Matthews, Nik, Misteli, Tom, Meshorer, Eran, Scaffidi, Paola

Volltext

Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak von Ivanovitch, Kenzo, Soro-Barrio, Pablo, Chakravarty, Probir, Jones, Rebecca A, Bell, Donald M, Mousavy Gharavy, S Neda, Stamataki, Despina, Delile, Julien, Smith, James C, Briscoe, James

Volltext

Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer von COWARD, Jermaine, KULBE, Hagen, SINGH, Naveena, AVRIL, Norbert, CUMMINGS, Jeff, REXHEPAJ, Elton, JIRSTRÖM, Karin, GALLAGHER, William M, BRENNAN, Donal J, MCNEISH, Lain A, BALKWILL, Frances R, CHAKRAVARTY, Probir, LEADER, David, VASSILEVA, Vessela, ANDREW LEINSTER, D, THOMPSON, Richard, SCHIOPPA, Tiziana, NEMETH, Jeffery, VERMEULEN, Jessica

Volltext