Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death von Magnaghi, Paola, D'Alessio, Roberto, Valsasina, Barbara, Avanzi, Nilla, Rizzi, Simona, Asa, Daniela, Gasparri, Fabio, Cozzi, Liviana, Cucchi, Ulisse, Orrenius, Christian, Polucci, Paolo, Ballinari, Dario, Perrera, Claudia, Leone, Antonella, Cervi, Giovanni, Casale, Elena, Xiao, Yang, Wong, Chihunt, Anderson, Daniel J, Galvani, Arturo, Donati, Daniele, O'Brien, Tom, Jackson, Peter K, Isacchi, Antonella

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Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors von Cervi, Giovanni, D'Alessio, Roberto, Bindi, Simona, Buffa, Laura, Burocchi, Alessia, Canevari, Giulia, Modugno, Michele, Motto, Ilaria, Saturno, Grazia, Orsini, Paolo

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Identification of N,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available C... von Brasca, Maria Gabriella, Amboldi, Nadia, Ballinari, Dario, Cameron, Alexander, Casale, Elena, Cervi, Giovanni, Colombo, Maristella, Colotta, Francesco, Croci, Valter, D’Alessio, Roberto, Fiorentini, Francesco, Isacchi, Antonella, Mercurio, Ciro, Moretti, Walter, Panzeri, Achille, Pastori, Wilma, Pevarello, Paolo, Quartieri, Francesca, Roletto, Fulvia, Traquandi, Gabriella, Vianello, Paola, Vulpetti, Anna, Ciomei, Marina

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Abstract 4036: NMS-0963 is a novel potent, selective and orally available Syk inhibitor with promising preclinical activity in diffuse large B-cell lymphoma von Saturno, Grazia, Modugno, Michele, Orsini, Paolo, Cervi, Giovanni, Buffa, Laura, Motto, Ilaria, Avanzi, Nilla, Montemartini, Marisa, Gasparri, Fabio, Texido, Gemma, Galvani, Arturo, Isacchi, Antonella

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Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases von Casuscelli, Francesco, Ardini, Elena, Avanzi, Nilla, Casale, Elena, Cervi, Giovanni, D’Anello, Matteo, Donati, Daniele, Faiardi, Daniela, Ferguson, Ronald D., Fogliatto, Gianpaolo, Galvani, Arturo, Marsiglio, Aurelio, Mirizzi, Danilo G., Montemartini, Marisa, Orrenius, Christian, Papeo, Gianluca, Piutti, Claudia, Salom, Barbara, Felder, Eduard R.

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Discovery of 2‑(Cyclohexylmethylamino)pyrimidines as a New Class of Reversible Valosine Containing Protein Inhibitors von Cervi, Giovanni, Magnaghi, Paola, Asa, Daniela, Avanzi, Nilla, Badari, Alessandra, Borghi, Daniela, Caruso, Michele, Cirla, Alessandra, Cozzi, Liviana, Felder, Eduard, Galvani, Arturo, Gasparri, Fabio, Lomolino, Antonio, Magnuson, Steven, Malgesini, Beatrice, Motto, Ilaria, Pasi, Maurizio, Rizzi, Simona, Salom, Barbara, Sorrentino, Graziella, Troiani, Sonia, Valsasina, Barbara, O’Brien, Thomas, Isacchi, Antonella, Donati, Daniele, D’Alessio, Roberto

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Bicyclic carbohydrate-derived scaffolds for combinatorial libraries von Cervi, Giovanni, Peri, Francesco, Battistini, Carlo, Gennari, Cesare, Nicotra, Francesco

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Thieno[3,2- c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity von Bindi, Simona, Fancelli, Daniele, Alli, Cristina, Berta, Daniela, Bertrand, Jay A., Cameron, Alexander D., Cappella, Paolo, Carpinelli, Patrizia, Cervi, Giovanni, Croci, Valter, D’Anello, Matteo, Forte, Barbara, Laura Giorgini, M., Marsiglio, Aurelio, Moll, Juergen, Pesenti, Enrico, Pittalà, Valeria, Pulici, Maurizio, Riccardi-Sirtori, Federico, Roletto, Fulvia, Soncini, Chiara, Storici, Paola, Varasi, Mario, Volpi, Daniele, Zugnoni, Paola, Vianello, Paola

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Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded prote... von Magnaghi, Paola, D'Alessio, Roberto, Valsasina, Barbara, Avanzi, Nilla R., Rizzi, Simona, Asa, Daniela, Gasparri, Fabio, Cozzi, Liviana, Cucchi, Ulisse, Orrenius, Cristian, Polucci, Paolo, Ballinari, Dario, Perrera, Claudia, Leone, Antonella, Cervi, Giovanni, Galvani, Arturo, Donati, Daniele, O'Brien, Tom, Jackson, Peter K., Isacchi, Antonella

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Identification of N ,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1 H -pyrazolo[4,3- h ]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Availa... von Brasca, Maria Gabriella, Amboldi, Nadia, Ballinari, Dario, Cameron, Alexander, Casale, Elena, Cervi, Giovanni, Colombo, Maristella, Colotta, Francesco, Croci, Valter, D’Alessio, Roberto, Fiorentini, Francesco, Isacchi, Antonella, Mercurio, Ciro, Moretti, Walter, Panzeri, Achille, Pastori, Wilma, Pevarello, Paolo, Quartieri, Francesca, Roletto, Fulvia, Traquandi, Gabriella, Vianello, Paola, Vulpetti, Anna, Ciomei, Marina

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PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS von CERVI, Giovanni, BUFFA, Laura, BINDI, Simona, MENICHINCHERI, Maria, MODUGNO, Michele, D'ALESSIO, Roberto

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PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS von CERVI, Giovanni, BUFFA, Laura, D ALESSIO, Roberto, BINDI, Simona, MENICHINCHERI, Maria, MODUGNO, Michele

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NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS von PAPEO, Gianluca Mariano Enrico, CERVI, Giovanni, BUFFA, Laura, UNZUE-LOPEZ, Andrea, KLEIN, Markus, COLOMBO, Riccardo, CALDARELLI, Marina, SIRRENBERG, Christian, ASA, Daniela Silvia

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PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS von CERVI, Giovanni, BUFFA, Laura, BINDI, Simona, MENICHINCHERI, Maria, MODUGNO, Michele, D'ALESSIO, Roberto

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3,4-DIHYDRO-2H-PYRAZINO[1,2-A]INDOL-1-ONE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM von PAPEO, GIANLUCA MARIANO ENRICO, D'ANELLO, MATTEO, CERVI, GIOVANNI, SALOM, BARBARA

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3,4-DIARIL PIRAZOIS COMO INIBIDORES DA PROTEÍNA QUINASE von GABRIELLA TRAQUANDI, MICHELE MODUGNO, STEFANO NUVOLONI, ALESSANDRA BADARI, CHIARA MARCHIONNI, FABIO ZUCCOTTO, SONIA BIONDARO, GIOVANNI CERVI, PAOLO TRIFIRO, MAURIZIO PULICI

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1H-Pyrido[3,4-B]indol-1-one and 2,3,4,9-Tetrahydro-1H-Beta-Carbolin-1-one Derivatives von Nicotra, Francesco, Vulpetti, Anna, Riccaboni, Mauro, Felder, Eduard, Gennari, Cesare, La Ferla, Barbara, Papeo, Gianluca Mariano Enrico, Cervi, Giovanni

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ChemInform Abstract: Critical Survey Covering 2007: Solid-Phase Synthesis von Carenzi, Davide, Cervi, Giovanni, Felder, Eduard, Mirizzi, Danilo, Salom, Barbara

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Pyrazolyl-pyrimidine derivatives as kinase inhibitors von CASUSCELLI FRANCESCO, DISINGRINI TERESA, QUARTIERI FRANCESCA, CALDARELLI MARINA, BRASCA MARIA GABRIELLA, CERVI GIOVANNI

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ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS von POSTERI, HELENA, MONTAGNOLI, ALESSIA, PAPEO, GIANLUCA MARIANO ENRICO, BERTRAND, JAY AARON, FORTE, BARBARA, SCOLARO, ALESSANDRA, ZUCCOTTO, FABIO, ORSINI, PAOLO, CERVI, GIOVANNI, LUPI, ROSITA

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