Genetics of height and risk of atrial fibrillation: A Mendelian randomization study von Levin, Michael G, Judy, Renae, Gill, Dipender, Vujkovic, Marijana, Verma, Shefali S, Bradford, Yuki, Ritchie, Marylyn D, Hyman, Matthew C, Nazarian, Saman, Rader, Daniel J, Voight, Benjamin F, Damrauer, Scott M

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Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine von Breitwieser, Gerda E, Cippitelli, Andrea, Wang, Yingcai, Pelletier, Oliver, Dershem, Ridge, Wei, Jianning, Toll, Lawrence, Fakhoury, Bianca, Brunori, Gloria, Metpally, Raghu, Carey, David J, Robishaw, Janet

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Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial von Damask, Amy, Steg, P. Gabriel, Schwartz, Gregory G., Szarek, Michael, Hagström, Emil, Badimon, Lina, Chapman, M. John, Boileau, Catherine, Tsimikas, Sotirios, Ginsberg, Henry N., Banerjee, Poulabi, Manvelian, Garen, Pordy, Robert, Hess, Sibylle, Overton, John D., Lotta, Luca A., Yancopoulos, George D., Abecasis, Goncalo R., Baras, Aris, Paulding, Charles

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Functional biology of the Steel syndrome founder allele and evidence for clan genomics derivation of COL27A1 pathogenic alleles worldwide von Gonzaga-Jauregui, Claudia, Yesil, Gozde, Nistala, Harikiran, Gezdirici, Alper, Bayram, Yavuz, Nannuru, Kalyan C, Pehlivan, Davut, Yuan, Bo, Jimenez, Johanna, Sahin, Yavuz, Paine, Ingrid S, Akdemir, Zeynep Coban, Rajamani, Saathyaki, Staples, Jeffrey, Dronzek, John, Howell, Kristen, Fatih, Jawid M, Smaldone, Silvia, Schlesinger, Alan E, Ramírez, Norman, Cornier, Alberto S, Kelly, Melissa A, Haber, Robert, Chim, Shek Man, Nieman, Kristy, Wu, Nan, Walls, Johnathon, Poueymirou, William, Siao, Chia-Jen, Sutton, V Reid, Williams, Marc S, Posey, Jennifer E, Gibbs, Richard A, Carlo, Simon, Tegay, David H, Economides, Aris N, Lupski, James R

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Heterozygosity for a Pathogenic Variant in SLC12A3 That Causes Autosomal Recessive Gitelman Syndrome Is Associated with Lower Serum Potassium von Wan, Xuesi, Perry, James, Zhang, Haichen, Jin, Feng, Ryan, Kathleen A, Van Hout, Cristopher, Reid, Jeffrey, Overton, John, Baras, Aris, Han, Zhe, Streeten, Elizabeth, Li, Yanbing, Mitchell, Braxton D, Shuldiner, Alan R, Fu, Mao

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Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting von Giontella, Alice, Sjögren, Marketa, Lotta, Luca A., Overton, John D., Baras, Aris, Minuz, Pietro, Fava, Cristiano, Melander, Olle

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The Phenotypic Spectrum of COL4A3 Heterozygotes von Solanki, Kaushal V., Hu, Yirui, Moore, Bryn S., Abedi, Vida, Avula, Venkatesh, Mirshahi, Tooraj, Strande, Natasha T., Bucaloiu, Ion D., Chang, Alexander R.

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Germline POT1 variants can predispose to myeloid and lymphoid neoplasms von Lim, Tristan L., Lieberman, David B., Davis, Adam R., Loren, Alison W., Hausler, Ryan, Bigdeli, Ashkan, Li, Yimei, Powers, Jacquelyn, Raper, Anna, Regeneron Genetics Center, Carty, Shannon A., Nathanson, Katherine L., Bagg, Adam, Hexner, Elizabeth O., Maxwell, Kara N., Morrissette, Jennifer J. D., Babushok, Daria V.

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Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke von Li, Jiang, Abedi, Vida, Zand, Ramin, Griessenauer, Christoph J.

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Exome sequencing and analysis of 454,787 UK Biobank participants von Backman, Joshua D., Li, Alexander H., Marcketta, Anthony, Sun, Dylan, Mbatchou, Joelle, Kessler, Michael D., Benner, Christian, Liu, Daren, Locke, Adam E., Balasubramanian, Suganthi, Yadav, Ashish, Banerjee, Nilanjana, Gillies, Christopher E., Damask, Amy, Liu, Simon, Bai, Xiaodong, Hawes, Alicia, Maxwell, Evan, Gurski, Lauren, Watanabe, Kyoko, Kosmicki, Jack A., Rajagopal, Veera, Mighty, Jason, Jones, Marcus, Mitnaul, Lyndon, Stahl, Eli, Coppola, Giovanni, Jorgenson, Eric, Habegger, Lukas, Salerno, William J., Shuldiner, Alan R., Lotta, Luca A., Overton, John D., Cantor, Michael N., Reid, Jeffrey G., Yancopoulos, George, Kang, Hyun M., Marchini, Jonathan, Baras, Aris, Abecasis, Gonçalo R., Ferreira, Manuel A. R.

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Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank von Jurgens, Sean J., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Pirruccello, James P., Halford, Jennifer L., Weng, Lu-Chen, Nauffal, Victor, Roselli, Carolina, Hall, Amelia W., Oetjens, Matthew T., Lagerman, Braxton, vanMaanen, David P., Aragam, Krishna G., Lunetta, Kathryn L., Haggerty, Christopher M., Lubitz, Steven A., Ellinor, Patrick T.

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Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish von Lynch, Megan T, Maloney, Kristin A, Xu, Huichun, Perry, James A, Center, Regeneron Genetics, Shuldiner, Alan R, Mitchell, Braxton D

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Classic Thrombophilias and Thrombotic Risk Among Middle-Aged and Older Adults: A Population-Based Cohort Study von Manderstedt, Eric, Lind-Halldén, Christina, Halldén, Christer, Elf, Johan, Svensson, Peter J, Dahlbäck, Björn, Engström, Gunnar, Melander, Olle, Baras, Aris, Lotta, Luca A, Zöller, Bengt

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Polygenic scores for low lung function and the future risk of adverse health outcomes von Zaigham, Suneela, Gonçalves, Isabel, Center, Regeneron Genetics, Engström, Gunnar, Sun, Jiangming

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Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals von Gao, Chuan, Marcketta, Anthony, Backman, Joshua D., O'Dushlaine, Colm, Staples, Jeffrey, Ferreira, Manuel Allen Revez, Lotta, Luca A., Overton, John D., Reid, Jeffrey G., Mirshahi, Tooraj, Regeneron Genetics Center, Geisinger Regeneron Discovehr Collaboration, Baras, Aris, Abecasis, Gonçalo, Shuldiner, Alan R., Van Hout, Cristopher V., McCarthy, Shane

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Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure von Levin, Michael G., Tsao, Noah L., Singhal, Pankhuri, Liu, Chang, Vy, Ha My T., Paranjpe, Ishan, Backman, Joshua D., Bellomo, Tiffany R., Bone, William P., Biddinger, Kiran J., Hui, Qin, Dikilitas, Ozan, Satterfield, Benjamin A., Yang, Yifan, Morley, Michael P., Bradford, Yuki, Burke, Megan, Reza, Nosheen, Charest, Brian, Judy, Renae L., Puckelwartz, Megan J., Hakonarson, Hakon, Khan, Atlas, Kottyan, Leah C., Kullo, Iftikhar, Luo, Yuan, McNally, Elizabeth M., Rasmussen-Torvik, Laura J., Day, Sharlene M., Do, Ron, Phillips, Lawrence S., Ellinor, Patrick T., Nadkarni, Girish N., Ritchie, Marylyn D., Arany, Zoltan, Cappola, Thomas P., Margulies, Kenneth B., Aragam, Krishna G., Haggerty, Christopher M., Joseph, Jacob, Sun, Yan V., Voight, Benjamin F., Damrauer, Scott M.

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Exome sequencing and characterization of 49,960 individuals in the UK Biobank von Van Hout, Cristopher V., Tachmazidou, Ioanna, Backman, Joshua D., Hoffman, Joshua D., Liu, Daren, Pandey, Ashutosh K., Gonzaga-Jauregui, Claudia, Khalid, Shareef, Ye, Bin, Banerjee, Nilanjana, Li, Alexander H., O’Dushlaine, Colm, Marcketta, Anthony, Staples, Jeffrey, Schurmann, Claudia, Hawes, Alicia, Maxwell, Evan, Barnard, Leland, Lopez, Alexander, Penn, John, Habegger, Lukas, Blumenfeld, Andrew L., Bai, Xiaodong, O’Keeffe, Sean, Yadav, Ashish, Praveen, Kavita, Jones, Marcus, Salerno, William J., Chung, Wendy K., Surakka, Ida, Willer, Cristen J., Hveem, Kristian, Leader, Joseph B., Carey, David J., Ledbetter, David H., Cardon, Lon, Yancopoulos, George D., Economides, Aris, Coppola, Giovanni, Shuldiner, Alan R., Balasubramanian, Suganthi, Cantor, Michael, Nelson, Matthew R., Whittaker, John, Reid, Jeffrey G., Marchini, Jonathan, Overton, John D., Scott, Robert A., Abecasis, Gonçalo R., Yerges-Armstrong, Laura, Baras, Aris

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Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies von Cavazos, Taylor B, Kachuri, Linda, Graff, Rebecca E, Nierenberg, Jovia L, Thai, Khanh K, Alexeeff, Stacey, Van Den Eeden, Stephen, Corley, Douglas A, Kushi, Lawrence H, Hoffmann, Thomas J, Ziv, Elad, Habel, Laurel A, Jorgenson, Eric, Sakoda, Lori C, Witte, John S

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A Genome-First Approach to Estimate Prevalence of Germline Pathogenic Variants and Risk of Pancreatic Cancer in Select Cancer Susceptibility Genes von Astiazaran-Symonds, Esteban, Kim, Jung, Haley, Jeremy S, Kim, Sun Young, Rao, H Shanker, Genetics Center, Regeneron, Carey, David J, Stewart, Douglas R, Goldstein, Alisa M

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Gene burden analysis identifies genes associated with increased risk and severity of adult-onset hearing loss in a diverse hospital-based cohort von Hui, Daniel, Mehrabi, Shadi, Quimby, Alexandra E, Chen, Tingfang, Chen, Sixing, Park, Joseph, Li, Binglan, Ruckenstein, Michael J, Rader, Daniel J, Ritchie, Marylyn D, Brant, Jason A, Epstein, Douglas J, Mathieson, Iain

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