A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse von Schotta, Gunnar, Sengupta, Roopsha, Kubicek, Stefan, Malin, Stephen, Kauer, Monika, Callén, Elsa, Celeste, Arkady, Pagani, Michaela, Opravil, Susanne, De La Rosa-Velazquez, Inti A, Espejo, Alexsandra, Bedford, Mark T, Nussenzweig, André, Busslinger, Meinrad, Jenuwein, Thomas

Volltext

MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals von Lou, Zhenkun, Minter-Dykhouse, Katherine, Franco, Sonia, Gostissa, Monica, Rivera, Melissa A., Celeste, Arkady, Manis, John P., van Deursen, Jan, Nussenzweig, André, Paull, Tanya T., Alt, Frederick W., Chen, Junjie

Volltext

Changes in Chromatin Structure and Mobility in Living Cells at Sites of DNA Double-Strand Breaks von Kruhlak, Michael J., Celeste, Arkady, Dellaire, Graham, Fernandez-Capetillo, Oscar, Müller, Waltraud G., McNally, James G., Bazett-Jones, David P., Nussenzweig, André

Volltext

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks von Celeste, Arkady, Fernandez-Capetillo, Oscar, Kruhlak, Michael J., Pilch, Duane R., Staudt, David W., Lee, Alicia, Bonner, Robert F., Bonner, William M., Nussenzweig, André

Volltext

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo von Pellegrini, Manuela, Celeste, Arkady, Difilippantonio, Simone, Guo, Rong, Wang, Weidong, Feigenbaum, Lionel, Nussenzweig, André

Volltext

Focusing on Foci: H2AX and the Recruitment of DNA-Damage Response Factors von Fernandez-Capetillo, Oscar, Celeste, Arkady, Nussenzweig, André

Volltext

H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility von Celeste, Arkady, Difilippantonio, Simone, Difilippantonio, Michael J., Fernandez-Capetillo, Oscar, Pilch, Duane R., Sedelnikova, Olga A., Eckhaus, Michael, Ried, Thomas, Bonner, William M., Nussenzweig, André

Volltext

Histone H2AX is integral to hypoxia-driven neovascularization von Economopoulou, Matina, Langer, Harald F, Celeste, Arkady, Orlova, Valeria V, Choi, Eun Young, Ma, Mingchao, Vassilopoulos, Athanassios, Callen, Elsa, Deng, Chuxia, Bassing, Craig H, Boehm, Manfred, Nussenzweig, Andre, Chavakis, Triantafyllos

Volltext

H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis von Fernandez-Capetillo, Oscar, Mahadevaiah, Shantha K., Celeste, Arkady, Romanienko, Peter J., Camerini-Otero, R.Daniel, Bonner, William M., Manova, Katia, Burgoyne, Paul, Nussenzweig, André

Volltext

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes von Callén, Elsa, Jankovic, Mila, Difilippantonio, Simone, Daniel, Jeremy A, Chen, Hua-Tang, Celeste, Arkady, Pellegrini, Manuela, McBride, Kevin, Wangsa, Danny, Bredemeyer, Andrea L, Sleckman, Barry P, Ried, Thomas, Nussenzweig, Michel, Nussenzweig, André

Volltext

Genomic Instability in Mice Lacking Histone H2AX von Celeste, Arkady, Petersen, Simone, Romanienko, Peter J., Fernandez-Capetillo, Oscar, Chen, Hua Tang, Sedelnikova, Olga A., Bernardo Reina-San-Martin, Coppola, Vincenzo, Meffre, Eric, Difilippantonio, Michael J., Redon, Christophe, Pilch, Duane R., Olaru, Alexandru, Eckhaus, Michael, Camerini-Otero, R. Daniel, Tessarollo, Lino, Livak, Ferenc, Manova, Katia, Bonner, William M., Nussenzweig, Michel C., Nussenzweig, André

Volltext

Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Clea... von Furuta, Takahisa, Takemura, Haruyuki, Liao, Zhi-Yong, Aune, Gregory J., Redon, Christophe, Sedelnikova, Olga A., Pilch, Duane R., Rogakou, Emmy P., Celeste, Arkady, Chen, Hua Tang, Nussenzweig, Andre, Aladjem, Mirit I., Bonner, William M., Pommier, Yves

Volltext

Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis von Difilippantonio, Simone, Celeste, Arkady, Kruhlak, Michael J, Lee, Youngsoo, Difilippantonio, Michael J, Feigenbaum, Lionel, Jackson, Stephen P, McKinnon, Peter J, Nussenzweig, André

Volltext

Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models von Difilippantonio, Simone, Celeste, Arkady, Fernandez-Capetillo, Oscar, Chen, Hua-Tang, Martin, Bernardo Reina San, Laethem, Francois Van, Yang, Yong-Ping, Petukhova, Galina V., Eckhaus, Michael, Feigenbaum, Lionel, Manova, Katia, Kruhlak, Michael, Camerini-Otero, R. Daniel, Sharan, Shyam, Nussenzweig, Michel, Nussenzweig, André

Volltext

Spatio-Temporal Dynamics of Chromatin Containing DNA Breaks von Kruhlak, Michael J., Celeste, Arkady, Nussenzweig, André

Volltext

Monitoring DNA Breaks in Optically Highlighted Chromatin in Living Cells by Laser Scanning Confocal Microscopy von Kruhlak, Michael J., Celeste, Arkady, Nussenzweig, André

Volltext

Ablation of TrkA function in the immune system causes B cell abnormalities von Coppola, Vincenzo, Barrick, Colleen A, Southon, Eileen A, Celeste, Arkady, Wang, Kathryn, Chen, Bei, Haddad, El-Bdaoui, Yin, Jian, Nussenzweig, Andre, Subramaniam, Arun, Tessarollo, Lino

Volltext

Ku86 Preserves Chromatin Integrity in Cells Adapted to High NaCl von Dmitrieva, Natalia I., Celeste, Arkady, Nussenzweig, André, Burg, Maurice B.

Volltext

DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1 von Fernandez-Capetillo, Oscar, Chen, Hua-Tang, Celeste, Arkady, Ward, Irene, Romanienko, Peter J., Morales, Julio C., Naka, Kazuhito, Xia, Zhenfang, Camerini-Otero, R. Daniel, Motoyama, Noboru, Carpenter, Phillip B., Bonner, William M., Chen, Junjie, Nussenzweig, André

Volltext

Alterations in the Chromatin Environment Following the Introduction of DNA Breaks von KRUHLAK, Michael, CELESTE, Arkady, CROUCH, Elizabeth, ORLOV, Marika, CASELLAS, Rafael, NUSSENZWEIG, Andre

Volltext