Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people von Rapsomaniki, Eleni, Dr, Timmis, Adam, Prof, George, Julie, PhD, Pujades-Rodriguez, Mar, PhD, Shah, Anoop D, MRCP, Denaxas, Spiros, PhD, White, Ian R, PhD, Caulfield, Mark J, Prof, Deanfield, John E, Prof, Smeeth, Liam, Prof, Williams, Bryan, Prof, Hingorani, Aroon, Prof, Hemingway, Harry, Prof

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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials von Mega, Jessica L, Dr, Stitziel, Nathan O, Dr, Smith, J Gustav, MD, Chasman, Daniel I, PhD, Caulfield, Mark J, Prof, Devlin, James J, PhD, Nordio, Francesco, PhD, Hyde, Craig L, PhD, Cannon, Christopher P, Prof, Sacks, Frank M, Prof, Poulter, Neil R, Prof, Sever, Peter S, Prof, Ridker, Paul M, Prof, Braunwald, Eugene, Prof, Melander, Olle, Prof, Kathiresan, Sekar, MD, Sabatine, Marc S, Prof

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Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial von Williams, Bryan, Prof, MacDonald, Thomas M, Prof, Morant, Steve, PhD, Webb, David J, Prof, Sever, Peter, Prof, McInnes, Gordon, Prof, Ford, Ian, Prof, Cruickshank, J Kennedy, Prof, Caulfield, Mark J, Prof, Salsbury, Jackie, Prof, Mackenzie, Isla, FRCP, Padmanabhan, Sandosh, FRCP, Brown, Morris J, Prof

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Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes von Wei, Wei, Schon, Katherine R., Elgar, Greg, Orioli, Andrea, Tanguy, Melanie, Giess, Adam, Tischkowitz, Marc, Caulfield, Mark J., Chinnery, Patrick F.

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The 100 000 Genomes Project: bringing whole genome sequencing to the NHS von Turnbull, Clare, Scott, Richard H, Thomas, Ellen, Jones, Louise, Murugaesu, Nirupa, Pretty, Freya Boardman, Halai, Dina, Baple, Emma, Craig, Clare, Hamblin, Angela, Henderson, Shirley, Patch, Christine, O’Neill, Amanda, Devereaux, Andrew, Smith, Katherine, Martin, Antonio Rueda, Sosinsky, Alona, McDonagh, Ellen M, Sultana, Razvan, Mueller, Michael, Smedley, Damian, Toms, Adam, Dinh, Lisa, Fowler, Tom, Bale, Mark, Hubbard, Tim, Rendon, Augusto, Hill, Sue, Caulfield, Mark J

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Advances in Blood Pressure Genomics von Munroe, Patricia B, Barnes, Michael R, Caulfield, Mark J

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ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon von Hartmann, Sylvia, Yasmeen, Summaira, Jacobs, Benjamin M., Denaxas, Spiros, Pirmohamed, Munir, Gamazon, Eric R., Caulfield, Mark J., Hemingway, Harry, Pietzner, Maik, Langenberg, Claudia

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Endothelial C-type natriuretic peptide maintains vascular homeostasis von Moyes, Amie J, Khambata, Rayomand S, Villar, Inmaculada, Bubb, Kristen J, Baliga, Reshma S, Lumsden, Natalie G, Xiao, Fang, Gane, Paul J, Rebstock, Anne-Sophie, Worthington, Roberta J, Simone, Michela I, Mota, Filipa, Rivilla, Fernando, Vallejo, Susana, Peiró, Concepción, Sánchez Ferrer, Carlos F, Djordjevic, Snezana, Caulfield, Mark J, MacAllister, Raymond J, Selwood, David L, Ahluwalia, Amrita, Hobbs, Adrian J

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Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia von Wallace, Chris, Newhouse, Stephen J., Braund, Peter, Zhang, Feng, Tobin, Martin, Falchi, Mario, Ahmadi, Kourosh, Dobson, Richard J., Marçano, Ana Carolina B., Hajat, Cother, Burton, Paul, Deloukas, Panagiotis, Brown, Morris, Connell, John M., Dominiczak, Anna, Lathrop, G. Mark, Webster, John, Farrall, Martin, Spector, Tim, Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.

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Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations von Balachandar, Srimmitha, Graves, Tamara J., Shimonty, Anika, Kerr, Katie, Kilner, Jill, Xiao, Sihao, Slade, Richard, Sroya, Manveer, Alikian, Mary, Curetean, Emanuel, Thomas, Ellen, McConnell, Vivienne P. M., McKee, Shane, Boardman‐Pretty, Freya, Devereau, Andrew, Fowler, Tom A., Caulfield, Mark J., Alton, Eric W., Ferguson, Teena, Redhead, Julian, McKnight, Amy J., Thomas, Geraldine A., Aldred, Micheala A., Shovlin, Claire L.

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Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of... von Yang, Wei, Ng, Fu Liang, Chan, Kenneth, Pu, Xiangyuan, Poston, Robin N, Ren, Meixia, An, Weiwei, Zhang, Ruoxin, Wu, Jingchun, Yan, Shunying, Situ, Haiteng, He, Xinjie, Chen, Yequn, Tan, Xuerui, Xiao, Qingzhong, Tucker, Arthur T, Caulfield, Mark J, Ye, Shu

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ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant von Pu, Xiangyuan, Xiao, Qingzhong, Kiechl, Stefan, Chan, Kenneth, Ng, Fu Liang, Gor, Shivani, Poston, Robin N., Fang, Changcun, Patel, Ashish, Senver, Ece C., Shaw-Hawkins, Sue, Willeit, Johann, Liu, Chuanju, Zhu, Jianhua, Tucker, Arthur T., Xu, Qingbo, Caulfield, Mark J., Ye, Shu

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Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomise... von Brown, Morris J, Prof, Williams, Bryan, Prof, Morant, Steve V, PhD, Webb, David J, Prof, Caulfield, Mark J, Prof, Cruickshank, J Kennedy, Prof, Ford, Ian, Prof, McInnes, Gordon, Prof, Sever, Peter, Prof, Salsbury, Jackie, RGN, Mackenzie, Isla S, FRCP, Padmanabhan, Sandosh, FRCP, MacDonald, Thomas M, Prof

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Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study von Kapil, Vikas, Khambata, Rayomand S, Robertson, Amy, Caulfield, Mark J, Ahluwalia, Amrita

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Extracellular volume quantification in isolated hypertension - changes at the detectable limits? von Treibel, Thomas A, Zemrak, Filip, Sado, Daniel M, Banypersad, Sanjay M, White, Steven K, Maestrini, Viviana, Barison, Andrea, Patel, Vimal, Herrey, Anna S, Davies, Ceri, Caulfield, Mark J, Petersen, Steffen E, Moon, James C

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Factor V Leiden, estrogen, and multimorbidity association with venous thromboembolism in a British-South Asian cohort von Magavern, Emma F., Smedley, Damian, Caulfield, Mark J.

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Personalized Antihypertensive Treatment Optimization With Smartphone-Enabled Remote Precision Dosing of Amlodipine During the COVID-19 Pandemic (PERSONAL-CovidBP Trial) von Collier, David J, Taylor, Mike, Godec, Thomas, Shiel, Julian, James, Rebecca, Chowdury, Yasmin, Ebano, Patrizia, Monk, Vivienne, Patel, Mital, Pheby, Jane, Pheby, Ruby, Foubister, Amanda, David, Clovel, Saxena, Manish, Richardson, Leanne, Siddle, James, Timlin, Gregor, Goldsmith, Paul, Deeming, Nicholas, Poulter, Neil R, Gabe, Rhian, McManus, Richard J, Caulfield, Mark J

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Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D st... von Raisi-Estabragh, Zahra, McCracken, Celeste, Bethell, Mae S, Cooper, Jackie, Cooper, Cyrus, Caulfield, Mark J, Munroe, Patricia B, Harvey, Nicholas C, Petersen, Steffen E

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Genes for blood pressure: an opportunity to understand hypertension von Ehret, Georg B, Caulfield, Mark J

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White Blood Cells and Blood Pressure: A Mendelian Randomization Study von Siedlinski, Mateusz, Jozefczuk, Ewelina, Xu, Xiaoguang, Teumer, Alexander, Evangelou, Evangelos, Schnabel, Renate B., Welsh, Paul, Maffia, Pasquale, Erdmann, Jeanette, Tomaszewski, Maciej, Caulfield, Mark J., Sattar, Naveed, Holmes, Michael V., Guzik, Tomasz J.

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