Protein-Based Virtual Screening of Chemical Databases. 1. Evaluation of Different Docking/Scoring Combinations von Bissantz, Caterina, Folkers, Gerd, Rognan, Didier

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A Medicinal Chemist’s Guide to Molecular Interactions von Bissantz, Caterina, Kuhn, Bernd, Stahl, Martin

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Protein-based virtual screening of chemical databases. II. Are homology models of g-protein coupled receptors suitable targets? von Bissantz, Caterina, Bernard, Philippe, Hibert, Marcel, Rognan, Didier

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Discovery of Highly Selective Brain-Penetrant Vasopressin 1a Antagonists for the Potential Treatment of Autism via a Chemogenomic and Scaffold Hopping Approach von Ratni, Hasane, Rogers-Evans, Mark, Bissantz, Caterina, Grundschober, Christophe, Moreau, Jean-Luc, Schuler, Franz, Fischer, Holger, Alvarez Sanchez, Ruben, Schnider, Patrick

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Translational PK/PD for the Development of Novel Antibiotics-A Drug Developer's Perspective von Bissantz, Caterina, Zampaloni, Claudia, David-Pierson, Pascale, Dieppois, Guennaelle, Guenther, Andreas, Trauner, Andrej, Winther, Lotte, Stubbings, William

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RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal m... von Grether, Uwe, Foxton, Richard H, Gruener, Sabine, Korn, Claudia, Kimbara, Atsushi, Osterwald, Anja, Zirwes, Elisabeth, Uhles, Sabine, Thoele, Janina, Colé, Nadine, Rogers-Evans, Mark, Röver, Stephan, Nettekoven, Matthias, Martin, Rainer E, Adam, Jean-Michel, Fingerle, Jürgen, Bissantz, Caterina, Guba, Wolfgang, Alker, André, Szczesniak, Anna M, Porter, Ross F, Toguri, Tom J, Revelant, Franco, Poirier, Agnès, Perret, Camille, Winther, Lotte, Caruso, Antonello, Fezza, Filomena, Maccarrone, Mauro, Kelly, Melanie E M, Fauser, Sascha, Ullmer, Christoph

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High-Throughput Modeling of Human G-Protein Coupled Receptors:  Amino Acid Sequence Alignment, Three-Dimensional Model Building, and Receptor Library Screening von Bissantz, Caterina, Logean, Antoine, Rognan, Didier

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Estimating Unbound Drug Concentrations in Simulated Human Lung Fluid: Relevance to Lung Antibiotic PKPD von Keemink, Janneke, Cantrill, Carina, Riboulet, William, Jurmanović, Stella, Pavlovski, Ivana, Bissantz, Caterina

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Impact of nutritional factors on in vitro PK/PD modelling of polymyxin B against various strains of Acinetobacter baumannii von Lacroix, Mathilde, Moreau, Jérémy, Zampaloni, Claudia, Bissantz, Caterina, Shirvani, Hamasseh, Marchand, Sandrine, Couet, William, Chauzy, Alexia

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In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam-β-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Comp... von Monogue, Marguerite L, Giovagnoli, Sara, Bissantz, Caterina, Zampaloni, Claudia, Nicolau, David P

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Stepwise Design of γ‑Secretase Modulators with an Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere von Rodríguez Sarmiento, Rosa María, Bissantz, Caterina, Bylund, Johan, Limberg, Anja, Neidhart, Werner, Jakob-Roetne, Roland, Wang, Lisha, Baumann, Karlheinz

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Translating pharmacology models effectively to predict therapeutic benefit von Dudal, Sherri, Bissantz, Caterina, Caruso, Antonello, David-Pierson, Pascale, Driessen, Wouter, Koller, Erich, Krippendorff, Ben-Fillippo, Lechmann, Martin, Olivares-Morales, Andrés, Paehler, Axel, Rynn, Caroline, Türck, Dietrich, Van De Vyver, Arthur, Wang, Ken, Winther, Lotte

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Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder von Schnider, Patrick, Bissantz, Caterina, Bruns, Andreas, Dolente, Cosimo, Goetschi, Erwin, Jakob-Roetne, Roland, Künnecke, Basil, Mueggler, Thomas, Muster, Wolfgang, Parrott, Neil, Pinard, Emmanuel, Ratni, Hasane, Risterucci, Céline, Rogers-Evans, Mark, von Kienlin, Markus, Grundschober, Christophe

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Novel Indane-Containing NBTIs with Potent Anti-Gram-Negative Activity and Minimal hERG Inhibition von Cumming, John G., Kreis, Lukas, Kühne, Holger, Wermuth, Roger, Vercruysse, Maarten, Cantrill, Carina, Bissantz, Caterina, Qiu, Hongxia, Kramer, Christian, Andreotti, Daniele, Fossati, Giacomo

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Can we discover pharmacological promiscuity early in the drug discovery process? von Peters, Jens-Uwe, Hert, Jérôme, Bissantz, Caterina, Hillebrecht, Alexander, Gerebtzoff, Grégori, Bendels, Stefanie, Tillier, Fabien, Migeon, Jacques, Fischer, Holger, Guba, Wolfgang, Kansy, Manfred

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2109. In vitro and in vivo Killing Kinetics of Zosurabalpin (RG6006) Against Acinetobacter baumannii von Erbetti, Isabelle, Ferrari, Livia, Ortombina, Alessia, Savoia, Paola, Felici, Antonio, Bissantz, Caterina, Zampaloni, Claudia

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Me-Talnetant and Osanetant Interact within Overlapping but Not Identical Binding Pockets in the Human Tachykinin Neurokinin 3 Receptor Transmembrane Domains von Malherbe, Pari, Bissantz, Caterina, Marcuz, Anne, Kratzeisen, Claudia, Zenner, Marie-Thérèse, Wettstein, Joseph G., Ratni, Hasane, Riemer, Claus, Spooren, Will

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Conformational Changes of G Protein-Coupled Receptors During Their Activation by Agonist Binding von Bissantz, Caterina

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Probing the Cysteine-34 Position of Endogenous Serum Albumin with Thiol-Binding Doxorubicin Derivatives. Improved Efficacy of an Acid-Sensitive Doxorubicin Derivative with Specific... von Kratz, Felix, Warnecke, André, Scheuermann, Karin, Stockmar, Cornelia, Schwab, Jürgen, Lazar, Peter, Drückes, Peter, Esser, Norbert, Drevs, Joachim, Rognan, Didier, Bissantz, Caterina, Hinderling, Caterina, Folkers, Gerd, Fichtner, Iduna, Unger, Clemens

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A novel antibiotic class targeting the lipopolysaccharide transporter von Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E., Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T., Lobritz, Michael A., Bradley, Kenneth A.

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