Alzheimer's-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition von Jiang, Ying, Mullaney, Kerry A, Peterhoff, Corrinne M, Che, Shaoli, Schmidt, Stephen D, Boyer-Boiteau, Anne, Ginsberg, Stephen D, Cataldo, Anne M, Mathews, Paul M, Nixon, Ralph A

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Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression von Ginsberg, Stephen D, Alldred, Melissa J, Counts, Scott E, Cataldo, Anne M, Neve, Rachael L, Jiang, Ying, Wuu, Joanne, Chao, Moses V, Mufson, Elliott J, Nixon, Ralph A, Che, Shaoli

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Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease von Yang, Dun-Sheng, Kumar, Asok, Stavrides, Philip, Peterson, Jesse, Peterhoff, Corrine M, Pawlik, Monika, Levy, Efrat, Cataldo, Anne M, Nixon, Ralph A

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Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression von Rao, Mala V, Mohan, Panaiyur S, Peterhoff, Corrinne M, Yang, Dun-Sheng, Schmidt, Stephen D, Stavrides, Philip H, Campbell, Jabbar, Chen, Yuanxin, Jiang, Ying, Paskevich, Peter A, Cataldo, Anne M, Haroutunian, Vahram, Nixon, Ralph A

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Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model von Choi, Jennifer H.K, Berger, Jason D, Mazzella, Matthew J, Morales-Corraliza, Jose, Cataldo, Anne M, Nixon, Ralph A, Ginsberg, Stephen D, Levy, Efrat, Mathews, Paul M

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Presenilin Mutations in Familial Alzheimer Disease and Transgenic Mouse Models Accelerate Neuronal Lysosomal Pathology von CATALDO, ANNE M, PETERHOFF, CORRINNE M, SCHMIDT, STEPHEN D, TERIO, NICOLE B, DUFF, KAREN, BEARD, MARGARET, MATHEWS, PAUL M, NIXON, RALPH A

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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons von Lie, Pearl P.Y., Yang, Dun-Sheng, Stavrides, Philip, Goulbourne, Chris N., Zheng, Ping, Mohan, Panaiyur S., Cataldo, Anne M., Nixon, Ralph A.

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Abnormalities in Mitochondrial Structure in Cells from Patients with Bipolar Disorder von Cataldo, Anne M, McPhie, Donna L, Lange, Nicholas T, Punzell, Steven, Elmiligy, Sarah, Ye, Nancy Z, Froimowitz, Michael P, Hassinger, Linda C, Menesale, Emily B, Sargent, Laura W, Logan, David J, Carpenter, Anne E, Cohen, Bruce M

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Macroautophagy: A Novel β-Amyloid Peptide-Generating Pathway Activated in Alzheimer's Disease von Yu, W. Haung, Cuervo, Ana Maria, Kumar, Asok, Peterhoff, Corrinne M., Schmidt, Stephen D., Lee, Ju-Hyun, Mohan, Panaiyur S., Mercken, Marc, Farmery, Mark R., Tjernberg, Lars O., Jiang, Ying, Duff, Karen, Uchiyama, Yasuo, Näslund, Jan, Mathews, Paul M., Cataldo, Anne M., Nixon, Ralph A.

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Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology: Accelerated Endocytosis Promotes Late Endocytic Defects von Cataldo, Anne M, Mathews, Paul M, Boiteau, Anne Boyer, Hassinger, Linda C, Peterhoff, Corrinne M, Jiang, Ying, Mullaney, Kerry, Neve, Rachael L, Gruenberg, Jean, Nixon, Ralph A

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Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome von Cataldo, Anne M., Petanceska, Suzana, Terio, Nicole B., Peterhoff, Corrinne M., Durham, Robert, Mercken, Marc, Mehta, Pankaj D., Buxbaum, Joseph, Haroutunian, Vahram, Nixon, Ralph A.

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Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system von Cataldo, Anne M, Barnett, Jody L, Berman, Stephen A, Li, Jinhe, Quarless, Shelley, Bursztajn, Sherry, Lippa, Carol, Nixon, Ralph A

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Detection of Intranasally Delivered Bone Marrow-Derived Mesenchymal Stromal Cells in the Lesioned Mouse Brain : A Cautionary Report von Chartoff, Elena H., Damez-Werno, Diane, Sonntag, Kai C., Hassinger, Linda, Kaufmann, Daniel E., Peterson, Jesse, McPhie, Donna, Cataldo, Anne M., Cohen, Bruce M.

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App Gene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome von Cataldo, Anne M, Petanceska, Suzana, Peterhoff, Corrinne M, Terio, Nicole B, Epstein, Charles J, Villar, Angela, Carlson, Elaine J, Staufenbiel, Matthias, Nixon, Ralph A

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The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis : A review von NIXON, Ralph A, CATALDO, Anne M, MATHEWS, Paul M

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Rab5 Mediates an Amyloid Precursor Protein Signaling Pathway That Leads to Apoptosis von Laifenfeld, Daphna, Patzek, Lucas J, McPhie, Donna L, Chen, Yuzhi, Levites, Yona, Cataldo, Anne M, Neve, Rachael L

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Increased Neuronal Endocytosis and Protease Delivery to Early Endosomes in Sporadic Alzheimer's Disease: Neuropathologic Evidence for a Mechanism of Increased beta -Amyloidogenesis von Cataldo, Anne M, Barnett, Jody L, Pieroni, Cristiana, Nixon, Ralph A

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In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model von Chen, Yuanxin, Dyakin, Victor V, Branch, Craig A, Ardekani, Babak, Yang, Dunsheng, Guilfoyle, David N, Peterson, Jesse, Peterhoff, Corrinne, Ginsberg, Stephen D, Cataldo, Anne M, Nixon, Ralph A

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The endosomal-lysosomal system of neurons: new roles von Nixon, Ralph A., Cataldo, Anne M.

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Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology von Cataldo, Anne M, Mathews, Paul M, Boiteau, Anne Boyer, Hassinger, Linda C, Peterhoff, Corrinne M, Jiang, Ying, Mullaney, Kerry, Neve, Rachael L, Gruenberg, Jean, Nixon, Ralph A

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