Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells von Lin, Zhixin, Santos, Sonia, Padilla, Karen, Printzenhoff, David, Castle, Neil A

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Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release von Alexandrou, Aristos J, Brown, Adam R, Chapman, Mark L, Estacion, Mark, Turner, Jamie, Mis, Malgorzata A, Wilbrey, Anna, Payne, Elizabeth C, Gutteridge, Alex, Cox, Peter J, Doyle, Rachel, Printzenhoff, David, Lin, Zhixin, Marron, Brian E, West, Christopher, Swain, Nigel A, Storer, R Ian, Stupple, Paul A, Castle, Neil A, Hounshell, James A, Rivara, Mirko, Randall, Andrew, Dib-Hajj, Sulayman D, Krafte, Douglas, Waxman, Stephen G, Patel, Manoj K, Butt, Richard P, Stevens, Edward B

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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels von McCormack, Ken, Santos, Sonia, Chapman, Mark L, Krafte, Douglas S, Marron, Brian E, West, Christopher W, Krambis, Michael J, Antonio, Brett M, Zellmer, Shannon G, Printzenhoff, David, Padilla, Karen M, Lin, Zhixin, Wagoner, P Kay, Swain, Nigel A, Stupple, Paul A, de Groot, Marcel, Butt, Richard P, Castle, Neil A

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Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough von Lee, Rhianna E, Lewis, Catherine A, He, Lihua, Bulik-Sullivan, Emily C, Gallant, Samuel C, Mascenik, Teresa M, Dang, Hong, Cholon, Deborah M, Gentzsch, Martina, Morton, Lisa C, Minges, John T, Theile, Jonathan W, Castle, Neil A, Knowles, Michael R, Kimple, Adam J, Randell, Scott H

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Pharmacological Removal of Human Ether-à-go-go-Related Gene Potassium Channel Inactivation by 3-Nitro-N-(4-phenoxyphenyl) Benzamide (ICA-105574) von Gerlach, Aaron C, Stoehr, Sally J, Castle, Neil A

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Voltage-gated potassium channels as therapeutic targets von Wulff, Heike, Castle, Neil A, Pardo, Luis A

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GI‐530159, a novel, selective, mechanosensitive two‐pore‐domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability von Loucif, Alexandre J C, Saintot, Pierre‐Philippe, Liu, Jia, Antonio, Brett M, Zellmer, Shannon G, Yoger, Katrina, Veale, Emma L, Wilbrey, Anna, Omoto, Kiyoyuki, Cao, Lishuang, Gutteridge, Alex, Castle, Neil A, Stevens, Edward B, Mathie, Alistair

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PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels von Wang, Lingxin, Zellmer, Shannon G, Printzenhoff, David M, Castle, Neil A

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Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation von Wang, Lingxin, Zellmer, Shannon G, Printzenhoff, David M, Castle, Neil A

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Aquaporins as targets for drug discovery von Castle, Neil A.

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Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes von Storer, R. Ian, Pike, Andy, Swain, Nigel A., Alexandrou, Aristos J., Bechle, Bruce M., Blakemore, David C., Brown, Alan D., Castle, Neil A., Corbett, Matthew S., Flanagan, Neil J., Fengas, David, Johnson, M. Scott, Jones, Lyn H., Marron, Brian E., Payne, C. Elizabeth, Printzenhoff, David, Rawson, David J., Rose, Colin R., Ryckmans, Thomas, Sun, Jianmin, Theile, Jonathan W., Torella, Rubben, Tseng, Elaine, Warmus, Joseph S.

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Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation von Wang, Lingxin, Zellmer, Shannon G., Printzenhoff, David M., Castle, Neil A.

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Discovery and in Vitro Optimization of 3‑Sulfamoylbenzamides as ROMK Inhibitors von Sammons, Matthew F, Kharade, Sujay V, Filipski, Kevin J, Boehm, Markus, Smith, Aaron C, Shavnya, Andre, Fernando, Dilinie P, Dowling, Matthew S, Carpino, Philip A, Castle, Neil A, Zellmer, Shannon G, Antonio, Brett M, Gosset, James R, Carlo, Anthony, Denton, Jerod S

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Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel von Gross, Michael F., Beaudoin, Serge, McNaughton-Smith, Grant, Amato, George S., Castle, Neil A., Huang, Christine, Zou, Anruo, Yu, Weifeng

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The Effect of κ-Opioid Receptor Agonists on Tetrodotoxin-Resistant Sodium Channels in Primary Sensory Neurons von Su, Xin, Castle, Neil A., Antonio, Brett, Roeloffs, Rosemarie, Thomas, James B., Krafte, Douglas S., Chapman, Mark L.

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Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel von Gross, Michael F., Castle, Neil A., Zou, Anruo, Wickenden, Alan D., Yu, Weifeng, Spear, Kerry L.

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Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough von Lee, Rhianna E, Lewis, Catherine A, He, Lihua, Bulik-Sullivan, Emily C, Gallant, Samuel C, Mascenik, Teresa M, Dang, Hong, Cholon, Deborah M, Gentzsch, Martina, Morton, Lisa C, Minges, John T, Theile, Jonathan W, Castle, Neil A, Knowles, Michael R, Kimple, Adam J, Randell, Scott H

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In vitro and in vivo characterization of a novel naphthylamide ATP‐sensitive K+ channel opener, A‐151892 von Gopalakrishnan, Murali, Buckner, Steven A, Shieh, Char‐Chang, Fey, Thomas, Fabiyi, Adebola, Whiteaker, Kristi L, Davis‐Taber, Rachel, Milicic, Ivan, Daza, Anthony V, Scott, Victoria E S, Castle, Neil A, Printzenhoff, David, London, Brecht, Turner, Sean C, Carroll, William A, Sullivan, James P, Coghlan, Michael J, Brune, Michael E

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Structure–activity relationship of a novel class of naphthyl amide KATP channel openers von Turner, Sean C, Carroll, William A, White, Tammie K, Brune, Michael E, Buckner, Steven A, Gopalakrishnan, Murali, Fabiyi, Adebola, Coghlan, Michael J, Scott, Victoria E, Castle, Neil A, Daza, Anthony V, Milicic, Ivan, Sullivan, James P

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Electrophysiological Analysis of Heterologously Expressed Kv and SK/IK Potassium Channels von Castle, Neil A., Wickenden, Alan D., Zou, Anruo

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