An inter-laboratory validation of a real time PCR assay to measure host excretion of bacterial pathogens, particularly of Mycobacterium bovis von Travis, Emma R, Gaze, William H, Pontiroli, Alessandra, Sweeney, Francis P, Porter, David, Mason, Sam, Keeling, Matthew J C, Jones, Rebecca M, Sawyer, Jason, Aranaz, Alicia, Rizaldos, Elena Castellanos, Cork, Jennifer, Delahay, Richard J, Wilson, Gavin J, Hewinson, R Glyn, Courtenay, Orin, Wellington, Elizabeth M H

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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation von Guha, Minakshi, Castellanos-Rizaldos, Elena, Makrigiorgos, G Mike

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Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model von Duquette, Mark, Sadow, Peter M, Husain, Amjad, Sims, Jennifer N, Antonello, Zeus A, Fischer, Andrew H, Song, Chen, Castellanos-Rizaldos, Elena, Makrigiorgos, G Mike, Kurebayashi, Junichi, Nose, Vania, Van Hummelen, Paul, Bronson, Roderick T, Vinco, Michelle, Giordano, Thomas J, Dias-Santagata, Dora, Pandolfi, Pier Paolo, Nucera, Carmelo

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COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing von Castellanos-Rizaldos, Elena, Milbury, Coren A., Guha, Minakshi, Makrigiorgos, G. Mike

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COLD-PCR amplification of bisulfite-converted DNA allows the enrichment and sequencing of rare un-methylated genomic regions von Castellanos-Rizaldos, Elena, Milbury, Coren A, Karatza, Elli, Chen, Clark C, Makrigiorgos, G Mike, Merewood, Anne

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Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion von Castellanos-Rizaldos, Elena, Milbury, Coren Audrey, Makrigiorgos, G Mike

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Exosome-Based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients von Castellanos-Rizaldos, Elena, Grimm, Dominik G, Tadigotla, Vasisht, Hurley, James, Healy, John, Neal, Patricia L, Sher, Mia, Venkatesan, Raajdeep, Karlovich, Chris, Raponi, Mitch, Krug, Anne, Noerholm, Mikkel, Tannous, Jihane, Tannous, Bakhos A, Raez, Luis E, Skog, Johan K

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates von Brown, Kirk M., Nair, Jayaprakash K., Janas, Maja M., Anglero-Rodriguez, Yesseinia I., Dang, Lan T. H., Peng, Haiyan, Theile, Christopher S., Castellanos-Rizaldos, Elena, Brown, Christopher, Foster, Donald, Kurz, Jeffrey, Allen, Jeffrey, Maganti, Rajanikanth, Li, Jing, Matsuda, Shigeo, Stricos, Matthew, Chickering, Tyler, Jung, Michelle, Wassarman, Kelly, Rollins, Jeff, Woods, Lauren, Kelin, Alex, Guenther, Dale C., Mobley, Melissa W., Petrulis, John, McDougall, Robin, Racie, Timothy, Bombardier, Jessica, Cha, Diana, Agarwal, Saket, Johnson, Lei, Jiang, Yongfeng, Lentini, Scott, Gilbert, Jason, Nguyen, Tuyen, Chigas, Samantha, LeBlanc, Sarah, Poreci, Urjana, Kasper, Anne, Rogers, Arlin B., Chong, Saeho, Davis, Wendell, Sutherland, Jessica E., Castoreno, Adam, Milstein, Stuart, Schlegel, Mark K., Zlatev, Ivan, Charisse, Klaus, Keating, Mark, Manoharan, Muthiah, Fitzgerald, Kevin, Wu, Jing-Tao, Maier, Martin A., Jadhav, Vasant

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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in... von McDougall, Robin, Ramsden, Diane, Agarwal, Sagar, Agarwal, Saket, Aluri, Krishna, Arciprete, Michael, Brown, Christopher, Castellanos-Rizaldos, Elena, Charisse, Klaus, Chong, Saeho, Cichocki, Joseph, Fitzgerald, Kevin, Goel, Varun, Gu, Yongli, Guenther, Dale, Habtemariam, Bahru, Jadhav, Vasant, Janas, Maja, Jayaraman, Muthusamy, Kurz, Jeffrey, Li, Jing, Liu, Ju, Liu, Xiumin, Liou, Steven, Maclauchlin, Chris, Maier, Martin, Manoharan, Muthiah, Nair, Jayaprakash K, Robbie, Gabriel, Schmidt, Karyn, Smith, Peter, Theile, Christopher, Vaishnaw, Akshay, Waldron, Scott, Xu, Yuanxin, Zhang, Xuemei, Zlatev, Ivan, Wu, Jing-Tao

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Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients von Castellanos-Rizaldos, Elena, Zhang, Xuan, Tadigotla, Vasisht R, Grimm, Dominik G, Karlovich, Chris, Raez, Luis E, Skog, Johan K

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Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates von Yu, Mikyung, Qin, June, Liu, Xiumin, Ramsden, Diane, Williams, Brian, Zlatev, Ivan, Guenther, Dale, Matsuda, Shigeo, Tymon, Roxanne, Darcy, Justin, Wong, Catrina, Tsung, Jamie, Zawaneh, Peter, Chong, Saeho, Theile, Christopher S, Taneja, Nathan, Rogers, Arlin, Liu, Ju, Castellanos-Rizaldos, Elena, Bond, Sarah, So, Kawai, Denoncourt, Jason, Castoreno, Adam, Manoharan, Muthiah, Wu, Jing-Tao, Fitzgerald, Kevin, Maier, Martin A, Jadhav, Vasant, Nair, Jayaprakash K

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Differential strand separation at critical temperature: a minimally disruptive enrichment method for low-abundance unknown DNA mutations von Guha, Minakshi, Castellanos-Rizaldos, Elena, Liu, Pingfang, Mamon, Harvey, Makrigiorgos, G Mike

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RT-qPCR Methods to Support Pharmacokinetics and Drug Mechanism of Action to Advance Development of RNAi Therapeutics von Castellanos-Rizaldos, Elena, Brown, Christopher R, Dennin, Sean, Kim, Joohwan, Gupta, Swati, Najarian, Diana, Gu, Yongli, Aluri, Krishna, Enders, Jennifer, Brown, Kirk, Xu, Yuanxin

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Single-tube, highly parallel mutation enrichment in cancer gene panels by use of temperature-tolerant COLD-PCR von Castellanos-Rizaldos, Elena, Richardson, Katherine, Lin, Rui, Wu, Grant, Makrigiorgos, Mike G

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DMSO increases mutation-scanning detection sensitivity in clinical samples using high resolution melting von Song, Chen, Castellanos-Rizaldos, Elena, Bejar, Rafael, Ebert, Benjamin L., Makrigiorgos, G. Mike

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Abstract LB-226: Exosomal liquid biopsy reveals mRNA and lincRNA biomarkers in early stage breast cancer patient plasma von Chakrabortty, Sudipto K., Kitchen, Robert R., Coticchia, Christine M., Tadigotla, Vasisht R., Eitan, Erez, Castellanos-Rizaldos, Elena, Bedford, Lisa, Badola, Sunita, Valentino, Michael D., Colafemina, Nicholas, Uchiyama, Hidefumi, Morken, Mario, Williams, Miguel, Vincent, Sylvie, Danaee, Hadi, Yu, Seth, Skog, Johan

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DMSO Increases Mutation Scanning Detection Sensitivity of High-Resolution Melting in Clinical Samples von Song, Chen, Castellanos-Rizaldos, Elena, Bejar, Rafael, Ebert, Benjamin L, Makrigiorgos, G Mike

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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation von Guha, Minakshi, Castellanos-Rizaldos, Elena, Makrigiorgos, G. Mike

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P3.02a-008 EML4-ALK in Plasma Exosomes from a Cohort of NSCLC Patients von Brinkmann, Kay, Enderle, Daniel, Flinspach, Claudia, Mueller, Romy, Hurley, James, Castellanos-Rizaldos, Elena, Brock, Graham, Skog, Johan, Noerholm, Mikkel

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P3.02a-008 EML4-ALK in Plasma Exosomes from a Cohort of NSCLC Patients: Topic: ALK Biomarkers von Brinkmann, Kay, Enderle, Daniel, Flinspach, Claudia, Mueller, Romy, Hurley, James, Castellanos-Rizaldos, Elena, Brock, Graham, Skog, Johan, Noerholm, Mikkel

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