Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15 von Guo, Yuna, Ayers, Jessica L., Carter, Kelly T., Wang, Ting, Maden, Sean K., Edmond, Darwin, Newcomb P, Polly, Li, Christopher, Ulrich, Cornelia, Yu, Ming, Grady, William M.

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Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer von Luo, Yanxin, Wong, Chao-Jen, Kaz, Andrew M, Dzieciatkowski, Slavomir, Carter, Kelly T, Morris, Shelli M, Wang, Jianping, Willis, Joseph E, Makar, Karen W, Ulrich, Cornelia M, Lutterbaugh, James D, Shrubsole, Martha J, Zheng, Wei, Markowitz, Sanford D, Grady, William M

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DNA methylation profile in CpG-depleted regions uncovers a high-risk subtype of early-stage colorectal cancer von Yu, Huichuan, Wang, Xiaolin, Bai, Liangliang, Tang, Guannan, Carter, Kelly T, Cui, Ji, Huang, Pinzhu, Liang, Li, Ding, Yanqing, Cai, Muyan, Huang, Meijin, Liu, Huanliang, Cao, Guangwen, Gallinger, Steven, Pai, Rish K, Buchanan, Daniel D, Win, Aung Ko, Newcomb, Polly A, Wang, Jianping, Grady, William M, Luo, Yanxin

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Subtypes of Barrett’s oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis von Yu, Ming, Maden, Sean K, Stachler, Matthew, Kaz, Andrew M, Ayers, Jessica, Guo, Yuna, Carter, Kelly T, Willbanks, Amber, Heinzerling, Tai J, O’Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K, Chak, Amitabh, Elliott, Robin, Willis, Joseph E, Markowitz, Sanford D, Grady, William M

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Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression von Sripathy, Smitha, Leko, Vid, Adrianse, Robin L., Loe, Taylor, Foss, Eric J., Dalrymple, Emily, Lao, Uyen, Gatbonton-Schwager, Tonibelle, Carter, Kelly T., Payer, Bernhard, Paddison, Patrick J., Grady, William M., Lee, Jeannie T., Bartolomei, Marisa S., Bedalov, Antonio

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Implications of Epigenetic Drift in Colorectal Neoplasia von Luebeck, Georg E, Hazelton, William D, Curtius, Kit, Maden, Sean K, Yu, Ming, Carter, Kelly T, Burke, Wynn, Lampe, Paul D, Li, Christopher I, Ulrich, Cornelia M, Newcomb, Polly A, Westerhoff, Maria, Kaz, Andrew M, Luo, Yanxin, Inadomi, John M, Grady, William M

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Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas von Yu, Ming, Carter, Kelly T, Baker, Kelsey K, Redman, Mary W, Wang, Ting, Vickers, Kathy, Li, Christopher I, Cohen, Stacey A, Krane, Mukta, Ose, Jennifer, Gigic, Biljana, Figueiredo, Jane C, Toriola, Adetunji T, Siegel, Erin M, Shibata, David, Schneider, Martin, Ulrich, Cornelia M, Dzubinski, Lynda A, Schoen, Robert E, Grady, William M

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Autoimmune Responses to the Brain After Stroke Are Associated With Worse Outcome von BECKER, Kyra J, KALIL, Angela J, TANZI, Pat, ZIERATH, Dannielle K, SAVOS, Anna V, MICHAEL GEE, J, HADWIN, Jessica, CARTER, Kelly T, SHIBATA, Dean, CAIN, Kevin C

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MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles von Yu, Ming, Carter, Kelly T, Makar, Karen W, Vickers, Kathy, Ulrich, Cornelia M, Schoen, Robert E, Brenner, Dean, Markowitz, Sanford D, Grady, William M

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Dysfunctional epigenetic aging of the normal colon and colorectal cancer risk von Wang, Ting, Maden, Sean K., Luebeck, Georg E., Li, Christopher I., Newcomb, Polly A., Ulrich, Cornelia M., Joo, Ji-Hoon E., Buchanan, Daniel D., Milne, Roger L., Southey, Melissa C., Carter, Kelly T., Willbanks, Amber R., Luo, Yanxin, Yu, Ming, Grady, William M.

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Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor‐beta signaling in mouse intestinal neoplasms von Morris, Shelli M., Davison, Jerry, Carter, Kelly T., O'Leary, Rachele M., Trobridge, Patty, Knoblaugh, Sue E., Myeroff, Lois L., Markowitz, Sanford D., Brett, Benjamin T., Scheetz, Todd E., Dupuy, Adam J., Starr, Timothy K., Grady, William M.

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Anamnestic Recall of Stroke-Related Deficits: An Animal Model von ZIERATH, Dannielle, HADWIN, Jessica, SAVOS, Anna, CARTER, Kelly T, KUNZE, Allison, BECKER, Kyra J

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Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus von Yu, Ming, O'Leary, Rachele M, Kaz, Andrew M, Morris, Shelli M, Carter, Kelly T, Chak, Amitabh, Chandar, Apoorva, Willis, Joseph E, Moinova, Helen R, Markowitz, Sanford D, Brenner, Dean E, Anandabapasathy, Sharmila, Westerhoff, Maria, Wong, Chao-Jen, Shaheen, Nicholas J, Chen, Yanwen, Barnholtz-Sloan, Jill S, Grady, William M

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Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers von Lao, Victoria Valinluck, Welcsh, Piri, Luo, Yanxin, Carter, Kelly T, Dzieciatkowski, Slavomir, Dintzis, Suzanne, Meza, Jane, Sarvetnick, Nora E, Monnat, Raymond J, Loeb, Lawrence A, Grady, William M

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Sa2000 Differential Methylation in Gene Bodies and Promoters in Barrett's Esophagus and Esophageal Adenocarcinoma Revealed by Genome-Wide Methylation Array Analysis von Kaz, Andrew, Chen, Yanwen, Barnholtz-Sloan, Jill, Carter, Kelly T, Willis, Joseph, Chak, Amitabh, Grady, William M

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Abstract 477: Elevated EVL methylation level in the normal colon mucosa is a potential risk biomarker for developing metachronous polyps von Yu, Ming, Wang, Ting, Carter, Kelly T., Baker, Kelsey, Redman, Mary W., Vickers, Kathy, Dzubinski, Lynda Ann, Schoen, Robert E., Grady, William M.

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TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation von Morris, S M, Carter, K T, Baek, J Y, Koszarek, A, Yeh, M M, Knoblaugh, S E, Grady, W M

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Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on Genome-wide Methylation Analysis von Yu, Ming, Maden, Sean, Stachler, Matthew, Kaz, Andrew M., Ayers, Jessica, Guo, Yuna, Carter, Kelly T., Willbanks, Amber, Heinzerling, Tai J., O’Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K., Chak, Amitabh, Elliot, Robin, Willis, Joseph E., Markowitz, Sanford D., Grady, William M.

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Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-[Beta] superfamily as a regulator of XIST expression von Sripathy, Smitha, Leko, Vid, Adrianse, Robin L, Loe, Taylor, Foss, Eric J, Dalrymple, Emily, Lao, Uyen, Gatbonton-Schwager, Tonibelle, Carter, Kelly T, Payer, Bernhard, Paddison, Patrick J, Grady, William M, Lee, Jeannie T, Bartolomei, Marisa S, Bedalov, Antonio

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Abstract 1157: Increased expression of RecQ helicases in sporadic primary colorectal cancers von Lao, Victoria Valinluck, Carter, Kelly T., Rabinovitch, Peter S., Welcsh, Piri, Grady, William M.

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