Lapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in Tumor von Spector, Neil L, Robertson, Faith C, Bacus, Sarah, Blackwell, Kimberly, Smith, Deborah A, Glenn, Kelli, Cartee, Leanne, Harris, Jennifer, Kimbrough, Carie L, Gittelman, Mark, Avisar, Eli, Beitsch, Peter, Koch, Kevin M

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Effect of lapatinib on oral digoxin absorption in patients von Koch, Kevin M., Smith, Deborah A., Botbyl, Jeff, Arya, Nikita, Briley, Linda P., Cartee, Leanne, White, Jane Holshouser, Beyer, Jennifer, Dar, Mohammed M., Chung, Hyun Choel, Chu, Quincy, Bang, Yung-Jue

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Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine von Stuyver, Lieven J, McBrayer, Tamara R, Whitaker, Tony, Tharnish, Phillip M, Ramesh, Mangala, Lostia, Stefania, Cartee, Leanne, Shi, Junxing, Hobbs, Ann, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J

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NCI 9922: Phase 2 study of ibrutinib in treatment-refractory distant metastatic cutaneous melanoma (DMCM) von Moschos, Stergios J., Eroglu, Zeynep, Gaughan, Elizabeth Mary, Medina, Theresa Michelle, Wang, Peng, Dees, Elizabeth Claire, Cartee, Leanne, Arrowood, Christy, Carson, Craig, Thomas, Nancy E, Ollila, David W., Nikolaishvilli-Feinberg, Nana, Ivy, S. Percy, Harris, Pamela Jo, Hurwitz, Herbert

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Effects of low-fat and high-fat meals on steady-state pharmacokinetics of lapatinib in patients with advanced solid tumours von Devriese, Lot A., Koch, Kevin M., Mergui-Roelvink, Marja, Matthys, Gemma M., Ma, Wen Wee, Robidoux, Andre, Stephenson, Joe J., Chu, Quincy S. C., Orford, Keith W., Cartee, Leanne, Botbyl, Jeff, Arya, Nikita, Schellens, Jan H. M.

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Abstract CT205: A phase I dose-escalation study of trametinib (T) in combination with continuous or intermittent GSK2126458 (GSK458) in patients (pts) with advanced solid tumors von Bedard, Philippe L., Grilley-Olson, Juneko E., Cornfeld, Mark, Cartee, Leanne, Warwick, Susan, Razak, Albiruni A.R., Stayner, Lee-Anne, Wu, Yuehui, Greenwood, Rebecca, Viana-Gilmartin, Veronica, Lee, Carrie B., Bendell, Johanna, Burris, Howard A., Gianni, Luca, Sessa, Cristiana, Infante, Jeffrey R., Fasolo, Angelica

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Abstract B155: A phase I study of the MEK inhibitor GSK1120212 (GSK212) in combination with PI3K/mTOR inhibitor GSK2126458 (GSK458) in patients with advanced solid tumors von Grilley-Olson, Juneko E., Bedard, Phillip, Fasolo, Angelica, Blackman, Samuel C., Cartee, Leanne, Baker-Neblett, Katherine L., Sun, Peng, Infante, Jeffrey R.

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Effects of Esomeprazole on the Pharmacokinetics of Lapatinib in Breast Cancer Patients von Koch, Kevin M., Im, Young-Hyuck, Kim, Sung-Bae, Urruticoechea Ribate, Ander, Stephenson, Joe, Botbyl, Jeffrey, Cartee, Leanne, Holshouser, Jane, Ridgway, Derry

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Abstract B140: In vitro sensitivity profiling identifies selectively responsive tumor types and molecular subtypes to the PI3K inhibitor GSK2126458 von Greshock, Joel, Hardwicke, Mary Ann, Conway, Theresa, Degenhardt, Yan, Cartee, Leanne, Moy, Christopher, Lager, Joanne, Wooster, Richard, Bachman, Kurtis

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Bioequivalence study with lapatinib powder for oral suspension and the original tablet formulation in cancer patients von Koch, Kevin M., Ferron-Brady, Geraldine, Lemmon, Colleen, Cartee, Leanne, Hollyfield, Hedy, D'Amelio Jr, Anthony M., Piepszak, Alexandra, Swaby, Ramona F., Curran, David, Arya, Niki

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The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human my... von CARTEE, Leanne, ZHILIANG WANG, DECKER, Roy H, CHELLAPPAN, Srikumar P, FUSARO, Gina, HIRSCH, Karen G, SANKALA, Heidi M, DENT, Paul, GRANT, Steven

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Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells expos... von Cartee, Leanne, Maggio, Sonia C, Smith, Rebecca, Sankala, Heidi M, Dent, Paul, Grant, Steven

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Protein Kinase C-dependent Activation of the Tumor Necrosis Factor Receptor-mediated Extrinsic Cell Death Pathway Underlies Enhanced Apoptosis in Human Myeloid Leukemia Cells Expos... von Leanne Cartee, Sonia C. Maggio, Rebecca Smith, Heidi M. Sankala, Paul Dent, Steven Grant

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Potent antiviral effect of Reverset in HIV-1-infected adults following a single oral dose von STUYVER, Lieven J, MCBRAYER, Tamara R, SCHÜRMANN, Dirk, KRAVEC, Irena, BEARD, Amanda, CARTEE, Leanne, SCHINAZI, Raymond F, DE LA ROSA, Abel, MURPHY, Robert L, OTTO, Michael J

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The cyclin-dependent kinase inhibitor flavopiridol disrupts sodium butyrate-induced p21WAF1/CIP1 expression and maturation while reciprocally potentiating apoptosis in human leukem... von Rosato, Roberto R, Almenara, Jorge A, Cartee, Leanne, Betts, Vicki, Chellappan, Srikumar P, Grant, Steven

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The Cyclin-dependent Kinase Inhibitor Flavopiridol Disrupts Sodium Butyrate-induced p21WAF1/CIP1 Expression and Maturation while Reciprocally Potentiating Apoptosis in Human Leukem... von Roberto R. Rosato, Jorge A. Almenara, Leanne Cartee, Vicki Betts, Srikumar P. Chellappan, Steven Grant

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Protein Kinase C Modulation and Anticancer Drug Response von Cartee, Leanne, Kucera, Gregory L.

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Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine von STUYVER, Lieven J, MCBRAYER, Tamara R, WATANABE, Kyoichi A, OTTO, Michael J, WHITAKER, Tony, THARNISH, Phillip M, RAMESH, Mangala, LOSTIA, Stefania, CARTEE, Leanne, JUNXING SHI, HOBBS, Ann, SCHINAZI, Raymond F

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Gemcitabine induces programmed cell death and activates protein kinase C in BG-1 human ovarian cancer cells von CARTEE, L, KUCERA, G. L

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Evaluation of GM-CSF mouthwash for prevention of chemotherapy-induced mucositis: a randomized, double-blind, dose-ranging study von Cartee, Leanne, Petros, William P., Rosner, Gary L., Gilbert, Colleen, Moore, Sarah, Affronti, Mary Lou, Hoke, James A., Hussein, Atif M., Ross, Maureen, Rubin, Peter, Vredenburgh, James J., Peters, William P.

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