Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes von Goodwin, Nicole C, Ding, Zhi-Ming, Harrison, Bryce A, Strobel, Eric D, Harris, Angela L, Smith, Melinda, Thompson, Andrea Y, Xiong, Wendy, Mseeh, Faika, Bruce, Debra J, Diaz, Damaris, Gopinathan, Suma, Li, Ling, O’Neill, Emily, Thiel, Mary, Wilson, Alan G. E, Carson, Kenneth G, Powell, David R, Rawlins, David B

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LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice von Powell, David R, Smith, Melinda G, Doree, Deon D, Harris, Angela L, Greer, Jennifer, DaCosta, Christopher M, Thompson, Andrea, Jeter-Jones, Sabrina, Xiong, Wendy, Carson, Kenneth G, Goodwin, Nicole C, Harrison, Bryce A, Rawlins, David B, Strobel, Eric D, Gopinathan, Suma, Wilson, Alan, Mseeh, Faika, Zambrowicz, Brian, Ding, Zhi-Ming

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Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa Using DNA-Encoded Small Molecule Library Screening von Valastyan, Julie S, Tota, Michael R, Taylor, Isabelle R, Stergioula, Vasiliki, Hone, Graham A. B, Smith, Chari D, Henke, Brad R, Carson, Kenneth G, Bassler, Bonnie L

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Genetic deletion of Mst1 alters T cell function and protects against autoimmunity von Salojin, Konstantin V, Hamman, Brian D, Chang, Wei Chun, Jhaver, Kanchan G, Al-Shami, Amin, Crisostomo, Jeannette, Wilkins, Carrie, Digeorge-Foushee, Ann Marie, Allen, Jason, Patel, Nita, Gopinathan, Suma, Zhou, Julia, Nouraldeen, Amr, Jessop, Theodore C, Bagdanoff, Jeffrey T, Augeri, David J, Read, Robert, Vogel, Peter, Swaffield, Jonathan, Wilson, Alan, Platt, Kenneth A, Carson, Kenneth G, Main, Alan, Zambrowicz, Brian P, Oravecz, Tamas

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Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase von Tarver, James E., Pabba, Praveen K., Barbosa, Joseph, Han, Qiang, Gardyan, Michael W., Brommage, Robert, Thompson, Andrea Y., Schmidt, James M., Wilson, Alan G.E., He, Wei, Lombardo, Victoria K., Carson, Kenneth G.

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Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime... von Bagdanoff, Jeffrey T, Donoviel, Michael S, Nouraldeen, Amr, Carlsen, Marianne, Jessop, Theodore C, Tarver, James, Aleem, Saadat, Dong, Li, Zhang, Haiming, Boteju, Lakmal, Hazelwood, Jill, Yan, Jack, Bednarz, Mark, Layek, Suman, Owusu, Iris B, Gopinathan, Suma, Moran, Liam, Lai, Zhong, Kramer, Jeff, Kimball, S. David, Yalamanchili, Padmaja, Heydorn, William E, Frazier, Kenny S, Brooks, Barbara, Brown, Philip, Wilson, Alan, Sonnenburg, William K, Main, Alan, Carson, Kenneth G, Oravecz, Tamas, Augeri, David J

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4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase von Han, Qiang, Pabba, Praveen K., Barbosa, Joseph, Mabon, Ross, Healy, Jason P., Gardyan, Michael W., Terranova, Kristen M., Brommage, Robert, Thompson, Andrea Y., Schmidt, James M., Wilson, Alan G.E., Xu, Xiaolian, Tarver, James E., Carson, Kenneth G.

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Synthesis and structure–Activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-Molecule antagonists for interleukin-8 receptor von Li, Jie Jack, Carson, Kenneth G, Trivedi, Bharat K, Yue, Wen Song, Ye, Qing, Glynn, Roberta A, Miller, Steven R, Connor, David T, Roth, Bruce D, Luly, Jay R, Low, Joseph E, Heilig, David J, Yang, Weixing, Qin, Shixin, Hunt, Stephen

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Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1) von Abdel-Magid, Ahmed F., Carson, Kenneth G., Harris, Bruce D., Maryanoff, Cynthia A., Shah, Rekha D.

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Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders von Bagdanoff, Jeffrey T, Donoviel, Michael S, Nouraldeen, Amr, Tarver, James, Fu, Qinghong, Carlsen, Marianne, Jessop, Theodore C, Zhang, Haiming, Hazelwood, Jill, Nguyen, Huy, Baugh, Simon D. P, Gardyan, Michael, Terranova, Kristen M, Barbosa, Joseph, Yan, Jack, Bednarz, Mark, Layek, Suman, Courtney, Lawrence F, Taylor, Jerry, Digeorge-Foushee, Ann Marie, Gopinathan, Suma, Bruce, Debra, Smith, Traci, Moran, Liam, O’Neill, Emily, Kramer, Jeff, Lai, Zhong, Kimball, S. David, Liu, Qingyun, Sun, Weimei, Yu, Sean, Swaffield, Jonathan, Wilson, Alan, Main, Alan, Carson, Kenneth G, Oravecz, Tamas, Augeri, David J

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Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors von Jessop, Theodore C., Tarver, James E., Carlsen, Marianne, Xu, Amy, Healy, Jason P., Heim-Riether, Alexander, Fu, Qinghong, Taylor, Jerry A., Augeri, David J., Shen, Min, Stouch, Terry R., Swanson, Ronald V., Tari, Leslie W., Hunter, Michael, Hoffman, Isaac, Keyes, Philip E., Yu, Xuan-Chuan, Miranda, Maricar, Liu, Qingyun, Swaffield, Jonathan C., David Kimball, S., Nouraldeen, Amr, Wilson, Alan G.E., Foushee, Ann Marie DiGeorge, Jhaver, Kanchan, Finch, Rick, Anderson, Steve, Oravecz, Tamas, Carson, Kenneth G.

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5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase von Tarver, James E., Jessop, Theodore C., Carlsen, Marianne, Augeri, David J., Fu, Qinghong, Healy, Jason P., Heim-Riether, Alexander, Xu, Amy, Taylor, Jerry A., Shen, Min, Keyes, Philip E., David Kimball, S., Yu, Xuan-Chuan, Miranda, Maricar, Liu, Qingyun, Swaffield, Jonathan C., Nouraldeen, Amr, Wilson, Alan G.E., Finch, Rick, Jhaver, Kanchan, Foushee, Ann Marie DiGeorge, Anderson, Steve, Oravecz, Tamas, Carson, Kenneth G.

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Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of ( E )-1-(4-((1 R ,2 S ,3 R )-1,2,3,4-Tetrahydroxybutyl)-1 H -imidazol-2-yl)ethan... von Bagdanoff, Jeffrey T., Donoviel, Michael S., Nouraldeen, Amr, Carlsen, Marianne, Jessop, Theodore C., Tarver, James, Aleem, Saadat, Dong, Li, Zhang, Haiming, Boteju, Lakmal, Hazelwood, Jill, Yan, Jack, Bednarz, Mark, Layek, Suman, Owusu, Iris B., Gopinathan, Suma, Moran, Liam, Lai, Zhong, Kramer, Jeff, Kimball, S. David, Yalamanchili, Padmaja, Heydorn, William E., Frazier, Kenny S., Brooks, Barbara, Brown, Philip, Wilson, Alan, Sonnenburg, William K., Main, Alan, Carson, Kenneth G., Oravecz, Tamas, Augeri, David J.

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Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures1 von Abdel-Magid, Ahmed F, Carson, Kenneth G, Harris, Bruce D, Maryanoff, Cynthia A, Shah, Rekha D

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Reductive amination of aldehydes and ketones by using sodium triacetoxyborohydride von Abdel-Magid, Ahmed F., Maryanoff, Cynthia A., Carson, Kenneth G.

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ISOTHIAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY von BI, Yingzhi, CARSON, Kenneth G, KUPER, Christian Josef, DEGORCE, Sebastien Louis, LEWIS, Arwel, HARRIMAN, Geraldine Cirillo

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Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers von Carson, John R, Raffa, Robert B, Carson, Kenneth G

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PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY von Bi, Yingzhi, Lewis, Arwel, Kuper, Christian Josef, Palomero-Vazquez, Maria Angel, Thangapandian, Sundarapandian, Harriman, Geraldine Cirillo, Degorce, Sebastien Louis, Whittaker, Benjamin Paul, Carson, Kenneth G

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PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY von BI, Yingzhi, CARSON, Kenneth G, KUPER, Christian Josef, DEGORCE, Sebastien Louis, LEWIS, Arwel, PALOMERO-VAZQUEZ, Maria Angel, THANGAPANDIAN, Sundarapandian, CHAPMAN, Robert Stuart Laurie, HARRIMAN, Geraldine Cirillo

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PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY von BI, Yingzhi, WHITTAKER, Benjamin Paul, CARSON, Kenneth G, KUPER, Christian Josef, DEGORCE, Sebastien Louis, LEWIS, Arwel, PALOMERO-VAZQUEZ, Maria Angel, THANGAPANDIAN, Sundarapandian, HARRIMAN, Geraldine Cirillo

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