Propagation of Tau Pathology in a Model of Early Alzheimer's Disease von de Calignon, Alix, Polydoro, Manuela, Suárez-Calvet, Marc, William, Christopher, Adamowicz, David H., Kopeikina, Kathy J., Pitstick, Rose, Sahara, Naruhiko, Ashe, Karen H., Carlson, George A., Spires-Jones, Tara L., Hyman, Bradley T.

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Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo von Busche, Marc Aurel, Wegmann, Susanne, Dujardin, Simon, Commins, Caitlin, Schiantarelli, Julia, Klickstein, Naomi, Kamath, Tarun V., Carlson, George A., Nelken, Israel, Hyman, Bradley T.

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How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders von Carlson, George A., Prusiner, Stanley B.

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Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components von Lester, Evan, Ooi, Felicia K., Bakkar, Nadine, Ayers, Jacob, Woerman, Amanda L., Wheeler, Joshua, Bowser, Robert, Carlson, George A., Prusiner, Stanley B., Parker, Roy

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Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain von Takeda, Shuko, Wegmann, Susanne, Cho, Hansang, DeVos, Sarah L., Commins, Caitlin, Roe, Allyson D., Nicholls, Samantha B., Carlson, George A., Pitstick, Rose, Nobuhara, Chloe K., Costantino, Isabel, Frosch, Matthew P., Müller, Daniel J., Irimia, Daniel, Hyman, Bradley T.

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Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration von Hoover, Brian R., Reed, Miranda N., Su, Jianjun, Penrod, Rachel D., Kotilinek, Linda A., Grant, Marianne K., Pitstick, Rose, Carlson, George A., Lanier, Lorene M., Yuan, Li-Lian, Ashe, Karen H., Liao, Dezhi

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy von Young, Zapporah T., Rauch, Jennifer N., Assimon, Victoria A., Jinwal, Umesh K., Ahn, Misol, Li, Xiaokai, Dunyak, Bryan M., Ahmad, Atta, Carlson, George A., Srinivasan, Sharan R., Zuiderweg, Erik R.P., Dickey, Chad A., Gestwicki, Jason E.

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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints von Minikel, Eric Vallabh, Zhao, Hien T, Le, Jason, O’Moore, Jill, Pitstick, Rose, Graffam, Samantha, Carlson, George A, Kavanaugh, Michael P, Kriz, Jasna, Kim, Jae Beom, Ma, Jiyan, Wille, Holger, Aiken, Judd, McKenzie, Deborah, Doh-ura, Katsumi, Beck, Matthew, O’Keefe, Rhonda, Stathopoulos, Jacquelyn, Caron, Tyler, Schreiber, Stuart L, Carroll, Jeffrey B, Kordasiewicz, Holly B, Cabin, Deborah E, Vallabh, Sonia M

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Enhanced Tau Aggregation in the Presence of Amyloid β von Bennett, Rachel E, DeVos, Sarah L, Dujardin, Simon, Corjuc, Bianca, Gor, Rucha, Gonzalez, Jose, Roe, Allyson D, Frosch, Matthew P, Pitstick, Rose, Carlson, George A, Hyman, Bradley T

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Caspase activation precedes and leads to tangles von de Calignon, Alix, Fox, Leora M., Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Spires-Jones, Tara L., Hyman, Bradley T.

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Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain von Kopeikina, Katherine J, Carlson, George A, Pitstick, Rose, Ludvigson, Adam E, Peters, Alan, Luebke, Jennifer I, Koffie, Robert M, Frosch, Matthew P, Hyman, Bradley T, Spires-Jones, Tara L

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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro von Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko

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Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy von Kopeikina, Katherine J, Wegmann, Susanne, Pitstick, Rose, Carlson, George A, Bacskai, Brian J, Betensky, Rebecca A, Hyman, Bradley T, Spires-Jones, Tara L

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Innate immunity receptor CD36 promotes cerebral amyloid angiopathy von Park, Laibaik, Zhou, Joan, Zhou, Ping, Pistick, Rose, Jamal, Sleiman El, Younkin, Linda, Pierce, Joseph, Arreguin, Andrea, Anrather, Josef, Younkin, Steven G., Carlson, George A., McEwen, Bruce S., ladecola, Costantino

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Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients von Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E., Trisini Lipsanopoulos, Ana T., Scherzer, Clemens R., Carlson, George A., Pitstick, Rose, Peskind, Elaine R., Raskind, Murray A., Li, Ge, Montine, Thomas J., Frosch, Matthew P., Hyman, Bradley T.

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Synaptic alterations in the rTg4510 mouse model of tauopathy von Kopeikina, Katherine J., Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A., Pitstick, Rose, Hyman, Bradley T., Spires-Jones, Tara L.

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Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo von DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T

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Severe neurodegeneration in brains of transgenic rats producing human tau prions von Ayers, Jacob, Lopez, T. Peter, Steele, Ian T., Oehler, Abby, Roman-Albarran, Rigo, Cleveland, Elisa, Chong, Alex, Carlson, George A., Condello, Carlo, Prusiner, Stanley B.

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Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3⁺ progenitors and peripheral neurons von George, Lynn, Chaverra, Marta, Wolfe, Lindsey, Thorne, Julian, Close-Davis, Mattheson, Eibs, Amy, Riojas, Vickie, Grindeland, Andrea, Orr, Miranda, Carlson, George A., Lefcort, Frances

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Region-specific Dissociation of Neuronal Loss and Neurofibrillary Pathology in a Mouse Model of Tauopathy von Spires, Tara L., Orne, Jennifer D., SantaCruz, Karen, Pitstick, Rose, Carlson, George A., Ashe, Karen H., Hyman, Bradley T.

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