Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs von Ishizawa, Jo, Kojima, Kensuke, McQueen, Teresa, Ruvolo, Vivian, Chachad, Dhruv, Nogueras-Gonzalez, Graciela M, Huang, Xuelin, Pierceall, William E, Dettman, E J, Cardone, Michael H, Shacham, Sharon, Konopleva, Marina, Andreeff, Michael

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Regulation of Cell Death Protease Caspase-9 by Phosphorylation von Cardone, Michael H., Roy, Natalie, Stennicke, Henning R., Salvesen, Guy S., Franke, Thomas F., Stanbridge, Eric, Frisch, Steven, Reed, John C.

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Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications von Bashari, Muhammad Hasan, Fan, Fengjuan, Vallet, Sonia, Sattler, Martin, Arn, Melissa, Luckner-Minden, Claudia, Schulze-Bergkamen, Henning, Zörnig, Inka, Marme, Frederik, Schneeweiss, Andreas, Cardone, Michael H, Opferman, Joseph T, Jäger, Dirk, Podar, Klaus

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BH3 profiling discriminates response to cytarabine-based treatment of acute myelogenous leukemia von Pierceall, William E, Kornblau, Steven M, Carlson, Nicole E, Huang, Xuelin, Blake, Noel, Lena, Ryan, Elashoff, Michael, Konopleva, Marina, Cardone, Michael H, Andreeff, Michael

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The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases von Cardone, Michael H, Salvesen, Guy S, Widmann, Christian, Johnson, Gary, Frisch, Steven M

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A Phase I/II Trial of Carfilzomib, Pegylated Liposomal Doxorubicin, and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma von Schroeder, Mark A, Fiala, Mark A, Huselton, Eric, Cardone, Michael H, Jaeger, Savina, Jean, Sae Rin, Shea, Kathryn, Ghobadi, Armin, Wildes, Tanya, Stockerl-Goldstein, Keith E, Vij, Ravi

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Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer von Vallet, Sonia, Fan, Fengjuan, Malvestiti, Stefano, Pecherstorfer, Martin, Sattler, Martin, Schneeweiss, Andreas, Schulze-Bergkamen, Henning, Opferman, Joseph T., Cardone, Michael H., Jäger, Dirk, Podar, Klaus

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Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines von Koss, Brian, Ryan, Jeremy, Budhraja, Amit, Szarama, Katherine, Yang, Xue, Bathina, Madhavi, Cardone, Michael H, Nikolovska-Coleska, Zaneta, Letai, Anthony, Opferman, Joseph T

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Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response von Whitsett, Timothy G, Mathews, Ian T, Cardone, Michael H, Lena, Ryan J, Pierceall, William E, Bittner, Michael, Sima, Chao, LoBello, Janine, Weiss, Glen J, Tran, Nhan L

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Mcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia von Pierceall, William E, Lena, Ryan J, Medeiros, Bruno C, Blake, Noel, Doykan, Camille, Elashoff, Michael, Cardone, Michael H, Walter, Roland B

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Measurements of Mcl-1 protein dependencies using dimerization-specific antibodies as predictive biomarkers for BH-3 mimetic class therapies in AML von Cardone, Michael H., Kinloch, Andrew, Canakci, Mine, Ge, Jingping

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Identifying Mcl-1 protein dependencies using dimerization-specific antibody biomarker for predicting response to targeted apoptosis inducing therapies von Cardone, Michael H., Jean, Sae Rin, Karakas, Bahriye, Kumar, Sonia, Narovlyansky, Max, Lim, Bora

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Anti-Apoptotic BCL-2 Family Members Confer Resistance to Calicheamicin-Based Antibody-Drug Conjugate Therapy of Acute Leukemia von Godwin, Colin D., Bates, Olivia M., Jean, Sae Rin, Laszlo, George S., Garling, Eliotte E., Beddoe, Mary E., Cardone, Michael H., Walter, Roland B.

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Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor von Luton, F, Cardone, M H, Zhang, M, Mostov, K E

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Phorbol Myristate Acetate-Mediated Stimulation of Transcytosis and Apical Recycling in MDCK Cells von Cardone, Michael H., Smith, Bradley L., Song, Wenxia, Mochly-Rosen, Daria, Mostov, Keith E.

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Signal Transduction by the Polymeric Immunoglobulin Receptor Suggests a Role in Regulation of Receptor Transcytosis von Cardone, Michael H., Smith, Bradley L., Mennitt, Patricia A., Mochly-Rosen, Daria, Silver, Randi B., Mostov, Keith E.

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An alvocidib-containing regimen is highly effective in AML patients through a mechanism dependent on MCL1 expression and function von Smith, B. Douglas, Warner, Steven L, Whatcott, Clifford, Siddiqui-Jain, Adam, Bahr, Brigham, Dettman, Elisha, Doykan, Camille, Cardone, Michael H., Weitman, Steven D., Bearss, David

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Mitochondrial priming of chronic lymphocytic leukemia patients associates Bcl-xL dependence with alvocidib response von Pierceall, W E, Warner, S L, Lena, R J, Doykan, C, Blake, N, Elashoff, M, Hoff, D V, Bearss, D J, Cardone, M H, Andritsos, L, Byrd, J C, Lanasa, M C, Grever, M R, Johnson, A J

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Abstract 338: Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response von Whitsett, Timothy G., Mathews, Ian T., Cardone, Michael H., Lena, Ryan J., Pierceall, William E., Bittner, Michael, Sima, Chao, LoBello, Janine, Weiss, Glen J., Tran, Nhan L.

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Abstract 907: Bcl-xL dependence predicts response to alvocidib in chronic lymphocytic leukemia patients von Pierceall, William E., Warner, Steven L., Lena, Ryan J., Doykan, Camille, Blake, Noel, Elashoff, Michael, Hoff, Daniel D. Von, Bearss, David J., Cardone, Michael H., Grever, Michael, Lanasa, Mark C., Byrd, John C., Johnson, Amy J.

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