Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor von Caravella, Justin A, Lin, Jian, Diebold, R. Bruce, Campbell, Ann-Marie, Ericsson, Anna, Gustafson, Gary, Wang, Zhongguo, Castro, Jennifer, Clarke, Andrea, Gotur, Deepali, Josephine, Helen R, Katz, Marie, Kershaw, Mark, Yao, Lili, Toms, Angela V, Barr, Kenneth J, Dinsmore, Christopher J, Walker, Duncan, Ashwell, Susan, Lu, Wei

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The deubiquitylase USP9X controls ribosomal stalling von Clancy, Anne, Heride, Claire, Pinto-Fernández, Adán, Elcocks, Hannah, Kallinos, Andreas, Kayser-Bricker, Katherine J, Wang, Weiping, Smith, Victoria, Davis, Simon, Fessler, Shawn, McKinnon, Crystal, Katz, Marie, Hammonds, Tim, Jones, Neil P, O'Connell, Jonathan, Follows, Bruce, Mischke, Steven, Caravella, Justin A, Ioannidis, Stephanos, Dinsmore, Christopher, Kim, Sunkyu, Behrens, Axel, Komander, David, Kessler, Benedikt M, Urbé, Sylvie, Clague, Michael J

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Therapeutic Proteins von Dimitrov, Dimiter S.

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Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists von Smalley, Jr, Terrence L, Boggs, Sharon, Caravella, Justin A, Chen, Lihong, Creech, Katrina L, Deaton, David N, Kaldor, Istvan, Parks, Derek J

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Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064 von Akwabi-Ameyaw, Adwoa, Bass, Jonathan Y., Caldwell, Richard D., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Jones, Stacey A., Kaldor, Istvan, Liu, Yaping, Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., III, Frank Navas, Parks, Derek J., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce

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The Drosophila Orphan Nuclear Receptor DHR38 Mediates an Atypical Ecdysteroid Signaling Pathway von Baker, Keith D., Shewchuk, Lisa M., Kozlova, Tatiana, Makishima, Makoto, Hassell, Annie, Wisely, Bruce, Caravella, Justin A., Lambert, Millard H., Reinking, Jeffrey L., Krause, Henry, Thummel, Carl S., Willson, Timothy M., Mangelsdorf, David J.

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Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene von Bass, Jonathan Y., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., Mills, Wendy Y., Navas, Frank, Parks, Derek J., Smalley, Terrence L., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce

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Molecular basis of USP7 inhibition by selective small-molecule inhibitors von Turnbull, Andrew P., Ioannidis, Stephanos, Krajewski, Wojciech W., Pinto-Fernandez, Adan, Heride, Claire, Martin, Agnes C. L., Tonkin, Louise M., Townsend, Elizabeth C., Buker, Shane M., Lancia, David R., Caravella, Justin A., Toms, Angela V., Charlton, Thomas M., Lahdenranta, Johanna, Wilker, Erik, Follows, Bruce C., Evans, Nicola J., Stead, Lucy, Alli, Cristina, Zarayskiy, Vladislav V., Talbot, Adam C., Buckmelter, Alexandre J., Wang, Minghua, McKinnon, Crystal L., Saab, Fabienne, McGouran, Joanna F., Century, Hannah, Gersch, Malte, Pittman, Marc S., Marshall, C. Gary, Raynham, Tony M., Simcox, Mary, Stewart, Lorna M. D., McLoughlin, Sheila B., Escobedo, Jaime A., Bair, Kenneth W., Dinsmore, Christopher J., Hammonds, Tim R., Kim, Sunkyu, Urbé, Sylvie, Clague, Michael J., Kessler, Benedikt M., Komander, David

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FXR agonist activity of conformationally constrained analogs of GW 4064 von Akwabi-Ameyaw, Adwoa, Bass, Jonathan Y., Caldwell, Richard D., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., Navas, Frank, Parks, Derek J., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Bruce Wisely, G.

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Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064 von Bass, Jonathan Y., Caldwell, Richard D., Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Madauss, Kevin P., Marr, Harry B., McFadyen, Robert B., Miller, Aaron B., Parks, Derek J., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce

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Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene von Akwabi-Ameyaw, Adwoa, Caravella, Justin A., Chen, Lihong, Creech, Katrina L., Deaton, David N., Madauss, Kevin P., Marr, Harry B., Miller, Aaron B., Navas, Frank, Parks, Derek J., Spearing, Paul K., Todd, Dan, Williams, Shawn P., Wisely, G. Bruce

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Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors von Lin, Jian, Lu, Wei, Caravella, Justin A, Campbell, Ann Marie, Diebold, R. Bruce, Ericsson, Anna, Fritzen, Edward, Gustafson, Gary R, Lancia, David R, Shelekhin, Tatiana, Wang, Zhongguo, Castro, Jennifer, Clarke, Andrea, Gotur, Deepali, Josephine, Helen R, Katz, Marie, Diep, Hien, Kershaw, Mark, Yao, Lili, Kauffman, Goss, Hubbs, Stephen E, Luke, George P, Toms, Angela V, Wang, Liann, Bair, Kenneth W, Barr, Kenneth J, Dinsmore, Christopher, Walker, Duncan, Ashwell, Susan

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Computational Methods to Predict Therapeutic Protein Aggregation von Buck, Patrick M., Kumar, Sandeep, Wang, Xiaoling, Agrawal, Neeraj J., Trout, Bernhardt L., Singh, Satish K.

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Engineering of Affibody Molecules for Therapy and Diagnostics von Feldwisch, Joachim, Tolmachev, Vladimir

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Correction: The deubiquitylase USP9X controls ribosomal stalling von Clancy, Anne, Heride, Claire, Pinto-Fernández, Adán, Elcocks, Hannah, Kallinos, Andreas, Kayser-Bricker, Katherine J, Wang, Weiping, Smith, Victoria, Davis, Simon, Fessler, Shawn, McKinnon, Crystal, Katz, Marie, Hammonds, Tim, Jones, Neil P, O'Connell, Jonathan, Follows, Bruce, Mischke, Steven, Caravella, Justin A, Ioannidis, Stephanos, Dinsmore, Christopher, Kim, Sunkyu, Behrens, Axel, Komander, David, Kessler, Benedikt M, Urbé, Sylvie, Clague, Michael J

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Discovery of Substituted Maleimides as Liver X Receptor Agonists and Determination of a Ligand-Bound Crystal Structure von Jaye, Michael C, Krawiec, John A, Campobasso, Nino, Smallwood, Angela, Qiu, Chunyan, Lu, Quinn, Kerrigan, John J, De Los Frailes Alvaro, Maite, Laffitte, Bryan, Liu, Wu-Schyong, Marino, Joseph P, Meyer, Craig R, Nichols, Jason A, Parks, Derek J, Perez, Paloma, Sarov-Blat, Lea, Seepersaud, Sheila D, Steplewski, Klaudia M, Thompson, Scott K, Wang, Ping, Watson, Mike A, Webb, Christine L, Haigh, David, Caravella, Justin A, Macphee, Colin H, Willson, Timothy M, Collins, Jon L

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Size-Exclusion Chromatography with Multi-angle Light Scattering for Elucidating Protein Aggregation Mechanisms von Sahin, Erinc, Roberts, Christopher J.

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Therapeutic Proteins: Methods and Protocols von Voynov, Vladimir, Caravella, Justin A

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High-Throughput Quantitative N-Glycan Analysis of Glycoproteins von Doherty, Margaret, McManus, Ciara A., Duke, Rebecca, Rudd, Pauline M.

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Highly covarying residues have a functional role in antibody constant domains von Proctor, Elizabeth A., Kota, Pradeep, Demarest, Stephen J., Caravella, Justin A., Dokholyan, Nikolay V.

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