Nonspecific cleavages arising from reconstitution of trypsin under mildly acidic conditions von Niu, Ben, Martinelli II, Michael, Jiao, Yang, Wang, Chunlei, Cao, Mingyan, Wang, Jihong, Meinke, Eric

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Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1 von Chen, Weimin, Pandey, Madhu, Sun, Hong, Rolong, Andrea, Cao, Mingyan, Liu, Dengfeng, Wang, Jihong, Zeng, Lingmin, Hunter, Alan, Lin, Shihua

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Analytical characterization of coformulated antibodies as combination therapy von Kim, Jun, Kim, Yoen Joo, Cao, Mingyan, De Mel, Niluka, Miller, Kenneth, Bee, Jared S., Wang, Jihong, Wang, Xiangyang, Albarghouthi, Methal

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Identification of a CE-SDS shoulder peak as disulfide-linked fragments from common CH2 cleavages in IgGs and IgG-like bispecific antibodies von Cao, Mingyan, Jiao, Yang, Parthemore, Conner, Korman, Samuel, Ma, Jiao, Hunter, Alan, Kilby, Greg, Chen, Xiaoyu

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Multiplex Bioanalytical Methods for Comprehensive Characterization and Quantification of the Unique Complementarity-Determining-Region Deamidation of MEDI7247, an Anti-ASCT2 Pyrrol... von Huang, Yue, Yuan, Jiaqi, Mu, Ruipeng, Kubiak, Robert J, Ball, Kathryn, Cao, Mingyan, Hussmann, G. Patrick, de Mel, Niluka, Liu, Dengfeng, Roskos, Lorin K, Liang, Meina, Rosenbaum, Anton I

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Atypical Asparagine Deamidation of NW Motif Significantly Attenuates the Biological Activities of an Antibody Drug Conjugate von Cao, Mingyan, Hussmann, G. Patrick, Tao, Yeqing, O’Connor, Ellen, Parthemore, Conner, Zhang-Hulsey, Diana, Liu, Dengfeng, Jiao, Yang, Mel, Niluka de, Prophet, Meagan, Korman, Samuel, Sonawane, Jaytee, Grigoriadou, Christina, Huang, Yue, Umlauf, Scott, Chen, Xiaoyu

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Correction: Theoretical predictions and experimental verifications of SERS detection in colorants von Cao, Mingyan, Chen, Jiamin, Sun, Xiaohong, Xie, Feng, Li, Boyan

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Theoretical predictions and experimental verifications of SERS detection in colorants von Cao, Mingyan, Chen, Jiamin, Sun, Xiaohong, Xie, Feng, Li, Boyan

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Effect of binder phases on the cavitation erosion behavior of HVOF sprayed WC-based coatings von Wang, Huanhuan, Wu, Yuping, Cheng, Jiangbo, Zhu, Shuaishuai, Cao, Mingyan, Hong, Sheng

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Characterization and Monitoring of a Novel Light-heavy-light Chain Mispair in a Therapeutic Bispecific Antibody von Cao, Mingyan, Parthemore, Conner, Jiao, Yang, Korman, Samuel, Aspelund, Matthew, Hunter, Alan, Kilby, Greg, Chen, Xiaoyu

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A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture von Wang, Chunlei, Vemulapalli, Bhargavi, Cao, Mingyan, Gadre, Dhanesh, Wang, Jihong, Hunter, Alan, Wang, Xiangyang, Liu, Dengfeng

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Characterization and quantification of succinimide using peptide mapping under low-pH conditions and hydrophobic interaction chromatography von Cao, Mingyan, Mulagapati, Sri Hari Raju, Vemulapalli, Bhargavi, Wang, Jihong, Saveliev, Sergei V., Urh, Marjeta, Hunter, Alan, Liu, Dengfeng

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A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins von Xu, Weichen, Jimenez, Rod Brian, Mowery, Rachel, Luo, Haibin, Cao, Mingyan, Agarwal, Nitin, Ramos, Irina, Wang, Xiangyang, Wang, Jihong

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Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis von Cao, Mingyan, De Mel, Niluka, Jiao, Yang, Howard, James, Parthemore, Conner, Korman, Samuel, Thompson, Christopher, Wendeler, Michaela, Liu, Dengfeng

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Characterization of N-Terminal Glutamate Cyclization in Monoclonal Antibody and Bispecific Antibody Using Charge Heterogeneity Assays and Hydrophobic Interaction Chromatography von Cao, Mingyan, De Mel, Niluka, Wang, Jihong, Parthemore, Conner, Jiao, Yang, Chen, Weimin, Lin, Shihua, Liu, Dengfeng, Kilby, Greg, Chen, Xiaoyu

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An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping von Cao, Mingyan, Xu, Weichen, Niu, Ben, Kabundi, Ivy, Luo, Haibin, Prophet, Meagan, Chen, Weimin, Liu, Dengfeng, Saveliev, Sergei V., Urh, Marjeta, Wang, Jihong

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Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability von Chung, Wai Keen, Russell, Brian, Yang, Yanhong, Handlogten, Michael, Hudak, Suzanne, Cao, Mingyan, Wang, Jihong, Robbins, David, Ahuja, Sanjeev, Zhu, Min

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Impact of enzymatic reduction on bivalent bispecific antibody fragmentation and loss of product purity upon reoxidation von Swope, Nicole, Chung, Wai Keen, Cao, Mingyan, Motabar, Dana, Liu, Dengfeng, Ahuja, Sanjeev, Handlogten, Michael

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A method to directly analyze free-drug–related species in antibody-drug conjugates without sample preparation von de Mel, Niluka, Mulagapati, Sri Hari Raju, Cao, Mingyan, Liu, Dengfeng

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Identification of a CE-SDS shoulder peak as disulfide-linked fragments from common C(H)2 cleavages in IgGs and IgG-like bispecific antibodies von Cao, Mingyan, Jiao, Yang, Parthemore, Conner, Korman, Samuel, Ma, Jiao, Hunter, Alan, Kilby, Greg, Chen, Xiaoyu

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