Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion von Hudak, Jason E, Canham, Stephen M, Bertozzi, Carolyn R

Volltext

Discovery and Structure-Based Design of Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Interaction von Ding, Jian, Liu, Lulu, Chiang, Ying-Ling, Zhao, Mengxi, Liu, Hejun, Yang, Fei, Shen, Lingling, Lin, Ying, Deng, Huiwen, Gao, Jingyan, Sage, David R., West, Laura, Llamas, Luis A., Hao, Xin, Kawatkar, Sameer, Li, En, Jain, Rishi K., Tallarico, John A., Canham, Stephen M., Wang, He

Volltext

Bile acid analogues are activators of pyrin inflammasome von Alimov, Irina, Menon, Suchithra, Cochran, Nadire, Maher, Rob, Wang, Qiong, Alford, John, Concannon, John B., Yang, Zinger, Harrington, Edmund, Llamas, Luis, Lindeman, Alicia, Hoffman, Gregory, Schuhmann, Tim, Russ, Carsten, Reece-Hoyes, John, Canham, Stephen M., Cai, Xinming

Volltext

Systematic Chemogenetic Library Assembly von Canham, Stephen M., Wang, Yuan, Cornett, Allen, Auld, Douglas S., Baeschlin, Daniel K., Patoor, Maude, Skaanderup, Philip R., Honda, Ayako, Llamas, Luis, Wendel, Greg, Mapa, Felipa A., Aspesi, Peter, Labbé-Giguère, Nancy, Gamber, Gabriel G., Palacios, Daniel S., Schuffenhauer, Ansgar, Deng, Zhan, Nigsch, Florian, Frederiksen, Mathias, Bushell, Simon M., Rothman, Deborah, Jain, Rishi K., Hemmerle, Horst, Briner, Karin, Porter, Jeffery A., Tallarico, John A., Jenkins, Jeremy L.

Volltext

Total Synthesis of (+)-Sieboldine A von Canham, Stephen M, France, David J, Overman, Larry E

Volltext

Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction von Ding, Jian, Li, Guo, Liu, Hejun, Liu, Lulu, Lin, Ying, Gao, Jingyan, Zhou, Guoqiang, Shen, Lingling, Zhao, Mengxi, Yu, Yanyan, Guo, Weihui, Hommel, Ulrich, Ottl, Johannes, Blank, Jutta, Aubin, Nicola, Wei, Yi, He, Hu, Sage, David R., Atadja, Peter W., Li, En, Jain, Rishi K., Tallarico, John A., Canham, Stephen M., Chiang, Ying-Ling, Wang, He

Volltext

Activation of human STING by a molecular glue-like compound von Li, Jie, Canham, Stephen M., Wu, Hua, Henault, Martin, Chen, Lihao, Liu, Guoxun, Chen, Yu, Yu, Gary, Miller, Howard R., Hornak, Viktor, Brittain, Scott M., Michaud, Gregory A., Tutter, Antonin, Broom, Wendy, Digan, Mary Ellen, McWhirter, Sarah M., Sivick, Kelsey E., Pham, Helen T., Chen, Christine H., Tria, George S., McKenna, Jeffery M., Schirle, Markus, Mao, Xiaohong, Nicholson, Thomas B., Wang, Yuan, Jenkins, Jeremy L., Jain, Rishi K., Tallarico, John A., Patel, Sejal J., Zheng, Lianxing, Ross, Nathan T., Cho, Charles Y., Zhang, Xuewu, Bai, Xiao-Chen, Feng, Yan

Volltext

Total Synthesis of (+)-Sieboldine A: Evolution of a Pinacol-Terminated Cyclization Strategy von Canham, Stephen M, France, David J, Overman, Larry E

Volltext

Toward the Single-Molecule Investigation of Organometallic Reaction Mechanisms: Single-Molecule Imaging of Fluorophore-Tagged Palladium(II) Complexes von Canham, Stephen M, Bass, Jonathan Y, Navarro, Oscar, Lim, Sung-Gon, Das, Neeladri, Blum, Suzanne A

Volltext

CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism von Cho, Hyelim, Shen, Qiong, Zhang, Lydia H., Okumura, Mikiko, Kawakami, Akinori, Ambrose, Jessi, Sigoillot, Frederic, Miller, Howard R., Gleim, Scott, Cobos-Correa, Amanda, Wang, Ying, Piechon, Philippe, Roma, Guglielmo, Eggimann, Fabian, Moore, Charles, Aspesi, Peter, Mapa, Felipa A., Burks, Heather, Ross, Nathan T., Krastel, Philipp, Hild, Marc, Maimone, Thomas J., Fisher, David E., Nomura, Daniel K., Tallarico, John A., Canham, Stephen M., Jenkins, Jeremy L., Forrester, William C.

Volltext

Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury von Larraufie, Marie-Hélène, Gao, Xiaolin, Xia, Xiaobo, Devine, Patrick J., Kallen, Joerg, Liu, Dong, Michaud, Gregory, Harsch, Andreas, Savage, Nik, Ding, Jian, Tan, Kian, Mihalic, Manuel, Roggo, Silvio, Canham, Stephen M., Bushell, Simon M., Krastel, Philipp, Gao, Jinhai, Izaac, Aude, Altinoglu, Erhan, Lustenberger, Philipp, Salcius, Michael, Harbinski, Fred, Williams, Eric T., Zeng, Liling, Loureiro, Joseph, Cong, Feng, Fryer, Christy J., Klickstein, Lloyd, Tallarico, John A., Jain, Rishi K., Rothman, Deborah M., Wang, Shaowen

Volltext

Design of potent antimalarials with generative chemistry von Godinez, William J., Ma, Eric J., Chao, Alexander T., Pei, Luying, Skewes-Cox, Peter, Canham, Stephen M., Jenkins, Jeremy L., Young, Joseph M., Martin, Eric J., Guiguemde, W. Armand

Volltext

Identification of an unexpected 2-oxonia[3,3]sigmatropic rearrangement/aldol pathway in the formation of oxacyclic rings. Total synthesis of (+)-aspergillin PZ von Canham, Stephen M., Overman, Larry E., Tanis, Paul S.

Volltext

Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids von Canham, Stephen M., Hafensteiner, Benjamin D., Lebsack, Alec D., May-Dracka, Tricia L., Nam, Sangkil, Stearns, Brian A., Overman, Larry E.

Volltext

Divergent Synthesis and Chemical Reactivity of Bicyclic Lactone Fragments of Complex Rearranged Spongian Diterpenes von Schnermann, Martin J, Beaudry, Christopher M, Genung, Nathan E, Canham, Stephen M, Untiedt, Nicholas L, Karanikolas, Breanne D. W, Sütterlin, Christine, Overman, Larry E

Volltext

Synthesis of Readily Cleavable Immobilized 1,10-Phenanthroline Resins von Slough, Greg A, Krchňák, Viktor, Helquist, Paul, Canham, Stephen M

Volltext

Identification of an unexpected 2-oxonia[3,3]sigmatropic rearrangement/aldol pathway in the formation of oxacyclic rings. Total synthesis of (+)-aspergillin PZ: Organic Synthesis-2... von CANHAM, Stephen M, OVERMAN, Larry E, TANIS, Paul S

Volltext

ChemInform Abstract: Total Synthesis of (+)-Sieboldine A von Canham, Stephen M., France, David J., Overman, Larry E.

Volltext

MESOPOROUS SILICA PARTICLES COMPOSITIONS FOR VIRAL DELIVERY von Canham, Stephen M, Koshy, Sandeep Tharian

Volltext bestellen

MESOPOROUS SILICA PARTICLES COMPOSITIONS FOR VIRAL DELIVERY von KOSHY, Sandeep, Tharian, CANHAM, Stephen, M

Volltext bestellen