Molecular biomarkers for lung adenocarcinoma von Calvayrac, Olivier, Pradines, Anne, Pons, Elvire, Mazières, Julien, Guibert, Nicolas

Volltext

RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non-Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway von Dubois, Fatéméh, Keller, Maureen, Calvayrac, Olivier, Soncin, Fabrice, Hoa, Lily, Hergovich, Alexander, Parrini, Maria-Carla, Mazières, Julien, Vaisse-Lesteven, Mélissa, Camonis, Jacques, Levallet, Guénaëlle, Zalcman, Gérard

Volltext

Early Steps of Resistance to Targeted Therapies in Non-Small-Cell Lung Cancer von Delahaye, Celia, Figarol, Sarah, Pradines, Anne, Favre, Gilles, Mazieres, Julien, Calvayrac, Olivier

Volltext

Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma von Bousquet Mur, Emilie, Bernardo, Sara, Papon, Laura, Mancini, Maicol, Fabbrizio, Eric, Goussard, Marion, Ferrer, Irene, Giry, Anais, Quantin, Xavier, Pujol, Jean-Louis, Calvayrac, Olivier, Moll, Herwig P, Glasson, Yaël, Pirot, Nelly, Turtoi, Andrei, Cañamero, Marta, Wong, Kwok-Kin, Yarden, Yosef, Casanova, Emilio, Soria, Jean-Charles, Colinge, Jacques, Siebel, Christian W, Mazieres, Julien, Favre, Gilles, Paz-Ares, Luis, Maraver, Antonio

Volltext

Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies von Figarol, Sarah, Delahaye, Célia, Gence, Rémi, Doussine, Aurélia, Cerapio, Juan Pablo, Brachais, Mathylda, Tardy, Claudine, Béry, Nicolas, Asslan, Raghda, Colinge, Jacques, Villemin, Jean-Philippe, Maraver, Antonio, Ferrer, Irene, Paz-Ares, Luis, Kessler, Linda, Burrows, Francis, Lajoie-Mazenc, Isabelle, Dongay, Vincent, Morin, Clara, Florent, Amélie, Pagano, Sandra, Taranchon-Clermont, Estelle, Casanova, Anne, Pradines, Anne, Mazieres, Julien, Favre, Gilles, Calvayrac, Olivier

Volltext

Thrombin and protease-activated receptors (PARs) in atherothrombosis von Lluis Martorell, José Martínez-González, Cristina Rodríguez, Maurizio Gentile, Olivier Calvayrac, Lina Badimon

Volltext

Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer von Laplagne, Chloé, Meddour, Sarah, Figarol, Sarah, Michelas, Marie, Calvayrac, Olivier, Favre, Gilles, Laurent, Camille, Fournié, Jean-Jacques, Cabantous, Stéphanie, Poupot, Mary

Volltext

Fibulin-5 Is Up-regulated by Hypoxia in Endothelial Cells through a Hypoxia-inducible Factor-1 (HIF-1α)-dependent Mechanism von Guadall, Anna, Orriols, Mar, Rodríguez-Calvo, Ricardo, Calvayrac, Olivier, Crespo, Javier, Aledo, Rosa, Martínez-González, José, Rodríguez, Cristina

Volltext

Synergistic Effect of Thrombin and CD40 Ligand on Endothelial Matrix Metalloproteinase-10 Expression and Microparticle Generation In Vitro and In Vivo von de Lizarrondo, Sara Martínez, Roncal, Carmen, Calvayrac, Olivier, Rodríguez, Cristina, Varo, Nerea, Purroy, Ana, Lorente, Leonardo, Rodríguez, José A, Doeuvre, Loïc, Hervás-Stubbs, Sandra, Angles-Cano, Eduardo, Páramo, José A, Martínez-González, José, Orbe, Josune

Volltext

The RAS‐related GTPase RHOB confers resistance to EGFR‐tyrosine kinase inhibitors in non‐small‐cell lung cancer via an AKT‐dependent mechanism von Calvayrac, Olivier, Mazières, Julien, Figarol, Sarah, Marty‐Detraves, Claire, Raymond‐Letron, Isabelle, Bousquet, Emilie, Farella, Magali, Clermont‐Taranchon, Estelle, Milia, Julie, Rouquette, Isabelle, Guibert, Nicolas, Lusque, Amélie, Cadranel, Jacques, Mathiot, Nathalie, Savina, Ariel, Pradines, Anne, Favre, Gilles

Volltext

Cytoplasmic p27Kip1 promotes tumorigenesis via suppression of RhoB activity von Calvayrac, Olivier, Nowosad, Ada, Cabantous, Stéphanie, Lin, Lin‐Po, Figarol, Sarah, Jeannot, Pauline, Serres, Murielle P, Callot, Caroline, Perchey, Renaud T, Creff, Justine, Taranchon‐Clermont, Estelle, Rouquette, Isabelle, Favre, Gilles, Pradines, Anne, Manenti, Stephane, Mazieres, Julien, Lee, Huei, Besson, Arnaud

Volltext

RhoB determines tumor aggressiveness in a murine EGFRL858R-induced adenocarcinoma model and is a potential prognostic biomarker for Lepidic lung cancer von Calvayrac, Olivier, Pradines, Anne, Raymond-Letron, Isabelle, Rouquette, Isabelle, Bousquet, Emilie, Lauwers-Cances, Valérie, Filleron, Thomas, Cadranel, Jacques, Beau-Faller, Michèle, Casanova, Anne, Milia, Julie, Favre, Gilles, Mazières, Julien

Volltext

Abstract 656: DNA repair-interfering molecule AsiDNA® overcomes resistance to tyrosine kinase inhibitors in lung cancer von Figarol, Sarah, Pagano, Sandra, Jdey, Wael, Guillaume, Hugo, Favre, Gilles, Calvayrac, Olivier

Volltext

Abstract 4078: Acquired resistance to PARP inhibitors evolves from drug-tolerant cells vulnerable to AsiDNA von Jdey, Wael, Calvayrac, Olivier, Maloudi, Orlane, Ubelmann, Florent, Favre, Gilles, Bono, Françoise

Volltext

RHOB expression controls the activity of serine/threonine protein phosphatase PP2A to modulate mesenchymal phenotype and invasion in non-small cell lung cancers von Calvayrac, Olivier, Pradines, Anne, Favre, Gilles

Volltext

NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells von Rodríguez-Calvo, Ricardo, Ferrán, Beatriz, Alonso, Judith, Martí-Pàmies, Ingrid, Aguiló, Silvia, Calvayrac, Olivier, Rodríguez, Cristina, Martínez-González, José

Volltext

Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury von Rodríguez-Calvo, Ricardo, Guadall, Anna, Calvayrac, Olivier, Navarro, María A, Alonso, Judith, Ferrán, Beatriz, de Diego, Alicia, Muniesa, Pedro, Osada, Jesús, Rodríguez, Cristina, Martínez-González, José

Volltext

NOR-1 modulates the inflammatory response of vascular smooth muscle cells by preventing NFκB activation von Calvayrac, Olivier, Rodríguez-Calvo, Ricardo, Martí-Pamies, Ingrid, Alonso, Judith, Ferrán, Beatriz, Aguiló, Silvia, Crespo, Javier, Rodríguez-Sinovas, Antonio, Rodríguez, Cristina, Martínez-González, José

Volltext

The Ras-related GTPase RhoB, a relevant actor in the adaptive resistance to EGFR tyrosine kinase inhibitors in lung cancers von Calvayrac, Olivier, Pradines, Anne, Mazières, Julien, Favre, Gilles

Volltext

Clinical and molecular analysis of lung cancers associated with fibrosing interstitial lung disease von Héluain, Valentin, Prévot, Grégoire, Cabarrou, Bastien, Calvayrac, Olivier, Taranchon- Clermont, Estelle, Didier, Alain, Tabourier-Gouin, Sandrine, Milia, Julie, Mazières, Julien

Volltext