1722-P: RIPK1 Promotes Thapsigargin-Induced ß-Cell Death Independent of Caspase 3/7 Activity In Vitro von MUKHERJEE, NOYONIKA, CONTRERAS, CHRISTOPHER J., LIN, LI, CAI, ERICA P., TEMPLIN, ANDREW T.

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Epigallocatechin Gallate (EGCG) and Rutin Suppress the Glucotoxicity through Activating IRS2 and AMPK Signaling in Rat Pancreatic β Cells von Cai, Erica P, Lin, Jen-Kun

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Timing is everything: Rb's choice in islet-cell fate von Cai, Erica P, Wu, Xiaohong, Zacksenhaus, Eldad, Woo, Minna

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FAK signalling controls insulin sensitivity through regulation of adipocyte survival von Luk, Cynthia T., Shi, Sally Yu, Cai, Erica P., Sivasubramaniyam, Tharini, Krishnamurthy, Mansa, Brunt, Jara J., Schroer, Stephanie A., Winer, Daniel A., Woo, Minna

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Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy von Cox, Aaron R, Barrandon, Ornella, Cai, Erica P, Rios, Jacqueline S, Chavez, Julia, Bonnyman, Claire W, Lam, Carol J, Yi, Peng, Melton, Douglas A, Kushner, Jake A

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RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity von Contreras, Christopher J., Mukherjee, Noyonika, Branco, Renato C.S., Lin, Li, Hogan, Meghan F., Cai, Erica P., Oberst, Andrew A., Kahn, Steven E., Templin, Andrew T.

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Protocol for genome-scale in vivo CRISPR screening to study protection of beta cells under autoimmunity in a type 1 diabetes mouse model von Li, Jian, Lee, Yu-Chi, Iessi, Isabela L., Wu, Chialing, Yi, Peng, Cai, Erica P.

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Dual Role of VAMP8 in Regulating Insulin Exocytosis and Islet β Cell Growth von Zhu, Dan, Zhang, Yi, Lam, Patrick P.L., Dolai, Subhankar, Liu, Yunfeng, Cai, Erica P., Choi, Diana, Schroer, Stephanie A., Kang, Youhou, Allister, Emma M., Qin, Tairan, Wheeler, Michael B., Wang, Cheng-Chun, Hong, Wan-Jin, Woo, Minna, Gaisano, Herbert Y.

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Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate von Cai, Erica P., Wu, Xiaohong, Schroer, Stephanie A., Elia, Andrew J., Nostro, M. Cristina, Zacksenhaus, Eldad, Woo, Minna

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Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action von Cai, Erica P., Luk, Cynthia T., Wu, Xiaohong, Schroer, Stephanie A., Shi, Sally Yu, Sivasubramaniyam, Tharini, Brunt, Jara J., Zacksenhaus, Eldad, Woo, Minna

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Protective Renalase Deficiency in β-Cells Shapes Immune Metabolism and Function in Autoimmune Diabetes von Bode, Kevin, MacDonald, Tara, Stewart, Taylor, Mendez, Bryhan, Cai, Erica P, Morrow, Noelle, Lee, Yu-Chi, Yi, Peng, Kissler, Stephan

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1724-P: Caspase 3/7 Activation and RIPK3 Are Dispensable for Synthetic hIAPP-Induced ß-Cell Death von MUKHERJEE, NOYONIKA, CONTRERAS, CHRISTOPHER J., LIN, LI, CAI, ERICA P., KAHN, STEVEN E., TEMPLIN, ANDREW T.

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Redundant role of the cytochrome c-mediated intrinsic apoptotic pathway in pancreatic β-cells von Choi, Diana, Schroer, Stephanie A, Lu, Shun Yan, Cai, Erica P, Hao, Zhenyue, Woo, Minna

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Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation von Luk, Cynthia T., Chan, Carmen K., Chiu, Felix, Shi, Sally Yu, Misra, Paraish S., Li, Yu Zhe, Pollock-Tahiri, Evan, Schroer, Stephanie A., Desai, Harsh R., Sivasubramaniyam, Tharini, Cai, Erica P., Krishnamurthy, Mansa, Han, Daniel J., Chowdhury, Apu, Aslam, Rukhsana, Yuen, Darren A., Hakem, Anne, Hakem, Razqallah, Woo, Minna

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DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice von Shi, Sally Yu, Lu, Shun-Yan, Sivasubramaniyam, Tharini, Revelo, Xavier S., Cai, Erica P., Luk, Cynthia T., Schroer, Stephanie A., Patel, Prital, Kim, Raymond H., Bombardier, Eric, Quadrilatero, Joe, Tupling, A. Russell, Mak, Tak W., Winer, Daniel A., Woo, Minna

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Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes von Cai, Erica P., Ishikawa, Yuki, Zhang, Wei, Leite, Nayara C., Li, Jian, Hou, Shurong, Kiaf, Badr, Hollister-Lock, Jennifer, Yilmaz, Nese Kurt, Schiffer, Celia A., Melton, Douglas A., Kissler, Stephan, Yi, Peng

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The redundant role of JAK2 in regulating pancreatic β-cell mass von Choi, Diana, Cai, Erica P., Woo, Minna

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Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice von Shi, Sally Yu, Luk, Cynthia T., Schroer, Stephanie A., Kim, Min Jeong, Dodington, David W., Sivasubramaniyam, Tharini, Lin, Lauren, Cai, Erica P., Lu, Shun-Yan, Wagner, Kay-Uwe, Bazinet, Richard P., Woo, Minna

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In Vivo Role of Focal Adhesion Kinase in Regulating Pancreatic β-Cell Mass and Function Through Insulin Signaling, Actin Dynamics, and Granule Trafficking von CAI, Erica P, CASIMIR, Marina, GAISANO, HerbertY, MACDONALD, Patrick E, WOO, Minna, SCHROER, Stephanie A, LUK, Cynthia T, SALLY YU SHI, CHOI, Diana, XIAO QING DAI, HAJMRLE, Catherine, SPIGELMAN, Aliya F, DAN ZHU

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In Vivo Knockdown of Adipocyte Erythropoietin Receptor Does Not Alter Glucose or Energy Homeostasis von Luk, Cynthia T, Shi, Sally Yu, Choi, Diana, Cai, Erica P, Schroer, Stephanie A, Woo, Minna

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