FLT3-targeted therapy restores GATA1 pathway function in NPM1/FLT3-ITD mutated acute myeloid leukaemia von Sorcini, D, Stella, A, Scialdone, A, Sartori, S, Marra, A, Rossi, R, De Falco, F, Adamo, F M, Dorillo, E, Geraci, C, Arcaleni, R, Rompietti, C, Esposito, A, Moretti, L, Mameli, M G, Martelli, M P, Falini, B, Sportoletti, P

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P458: TRANSCRIPTIONAL AND TRANSLATIONAL SIGNATURES OF TRIPLE MUTATED DNMT3AKO/FLT3ITD/NPM1C MICE SHOW ALTERED RNAS PROCESSING AND CELL CYCLE PROGRESSION von Scialdone, A., Sorcini, D., Stella, A., Tini, V., Marra, A., Rompietti, C., De Falco, F., Dorillo, E., Adamo, F. M., Barcelos, E. C., Arcaleni, R., Martelli, M. P., Sportoletti°, P., Falini°, ° co‐last author, B.

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S139: BCOR DELETION SUSTAINS NOTCH1 SIGNALLING ACTIVATION TO ACCELERATE CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) PROGRESSION TOWARD RICHTER TRANSFORMATION IN MICE von Rompietti, C., Sorcini, D., De Falco, F., Dorillo, E., Adamo, F. M., Silva Barcelos, E. C., Stella, A., Scialdone, A., Esposito, A., Arcaleni, R., Bigerna, B., Martino, G., Moretti, L., Mameli, M. G., Geraci, C., Sandoletti, L., Cipiciani, A., Rosati, E., Falini, B., Sportoletti, P.

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Blockade of oncogenic notch1 with the new serca inhibitor cad204520 in t-cell acute lymphoblastic leukemia von M. Marchesini, A. Gherli, A. Montanaro, C. Sorrentino, L. Pagliaro, C. Rompietti, S. Kitara, F. Rizzi, D. Stilli, R. La Starza, C. Mecucci, K. Stegmaier, A.M. Lund Winter, P. Sportoletti, M. Bublitz, W. Dalby-Brown, G. Roti

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PF158 TARGETING ONCOGENIC NOTCH1 IN T‐CELL ACUTE LYMPHOBLASTIC LEUKEMIA WITH A NEW SELECTIVE SERCA INHIBITOR CAD204520 von Marchesini, M., Gherli, A., Winter, A.‐M. Lund, Patrizi, L., Kitara, S., Montanaro, A., Rompietti, C., Sorrentino, C., Stilli, D., Rizzi, F., Loiacono, C., Pagliaro, L., La Starza, R., Mecucci, C., Aversa, F., Sportoletti, P., Dalby‐Brown, W., Roti, G.

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PB1882 DECONSTRUCTING RICHTER SYNDROME TUMOR NICHE: JAGGED‐1 LIGAND LEADS THE WAY von Marra, A., Laurenti, M.E., Baldoni, S., Sorcini, D., Pasquino, S., Giansanti, M., Bigerna, B., Rompietti, C., De Falco, F., Del Papa, B., Martino, G., Ascani, S., Mecucci, C., Rosati, E., Sportoletti, P.

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New hybrid polymeric liquid chromatography chiral stationary phase prepared by surface-initiated polymerization von Gasparrini, F., Misiti, D., Rompietti, R., Villani, C.

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Platelet secretion: indiscriminately spewed forth or highly orchestrated? von WHITE, G. C., ROMPIETTI, R.

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Stereomutations of Atropisomers of Sterically Hindered Salophen Ligands von Dalla Cort, Antonella, Gasparrini, Francesco, Lunazzi, Lodovico, Mandolini, Luigi, Mazzanti, Andrea, Pasquini, Chiara, Pierini, Marco, Rompietti, Romina, Schiaffino, Luca

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Adsorption Equilibria of Benzodiazepines on a Hybrid Polymeric Chiral Stationary Phase von Cavazzini, Alberto, Dondi, Francesco, Marmai, Stefania, Minghini, Erik, Massi, Alessandro, Villani, Claudio, Rompietti, Romina, Gasparrini, Francesco

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Conformational Studies by Dynamic NMR. 100. Enantiomerization Process of Stereolabile Atropisomers in Pyridine-Substituted Adamantane Derivatives von Casarini, Daniele, Coluccini, Carmine, Lunazzi, Lodovico, Mazzanti, Andrea, Rompietti, Romina

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