Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation von Weber, Ross A., Yen, Frederick S., Nicholson, Shirony P.V., Alwaseem, Hanan, Bayraktar, Erol C., Alam, Mohammad, Timson, Rebecca C., La, Konnor, Abu-Remaileh, Monther, Molina, Henrik, Birsoy, Kıvanç

Volltext

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides von Birsoy, Kıvanç, Possemato, Richard, Lorbeer, Franziska K., Bayraktar, Erol C., Thiru, Prathapan, Yucel, Burcu, Wang, Tim, Chen, Walter W., Clish, Clary B., Sabatini, David M.

Volltext

MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L von Ma, Xinyu R., Alugubelli, Yugendar R., Ma, Yuying, Vatansever, Erol C., Scott, Danielle A., Qiao, Yuchen, Yu, Ge, Xu, Shiqing, Liu, Wenshe Ray

Volltext

Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs von Minton, Denise R., Nam, Minwoo, McLaughlin, Daniel J., Shin, Jong, Bayraktar, Erol C., Alvarez, Samantha W., Sviderskiy, Vladislav O., Papagiannakopoulos, Thales, Sabatini, David M., Birsoy, Kıvanç, Possemato, Richard

Volltext

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo von Bayraktar, Erol C., Baudrier, Lou, Özerdem, Ceren, Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Cangelosi, Andrew L., Sabatini, David M., Birsoy, Kıvanç, Chen, Walter W.

Volltext

Bepridil is potent against SARS-CoV-2 in vitro von Vatansever, Erol C., Yang, Kai S., Drelich, Aleksandra K., Kratch, Kaci C., Cho, Chia-Chuan, Kempaiah, Kempaiah Rayavara, Hsu, Jason C., Mellott, Drake M., Xu, Shiqing, Tseng, Chien-Te K., Liu, Wenshe Ray

Volltext

A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors von Yang, Kai S., Ma, Xinyu R., Ma, Yuying, Alugubelli, Yugendar R., Scott, Danielle A., Vatansever, Erol C., Drelich, Aleksandra K., Sankaran, Banumathi, Geng, Zhi Z., Blankenship, Lauren R., Ward, Hannah E., Sheng, Yan J., Hsu, Jason C., Kratch, Kaci C., Zhao, Baoyu, Hayatshahi, Hamed S., Liu, Jin, Li, Pingwei, Fierke, Carol A., Tseng, Chien‐Te K., Xu, Shiqing, Liu, Wenshe Ray

Volltext

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability von Unlu, Gokhan, Prizer, Benjamin, Erdal, Ranya, Yeh, Hsi-Wen, Bayraktar, Erol C., Birsoy, Kıvanç

Volltext

Pigmented Epithelioid Melanocytomas and Their Mimics; Focus on Their Novel Molecular Findings von Bayraktar, Erol C, Jour, George

Volltext

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability von Unlu, Gokhan, Prizer, Benjamin, Erdal, Ranya, Yeh, Hsi-Wen, Bayraktar, Erol C., Birsoy, Kıvanç

Volltext

Regularized estimation of vertical total electron content from Global Positioning System data von Arikan, F., Erol, C. B., Arikan, O.

Volltext

A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds von Vatansever, Erol C., Yang, Kai S., Geng, Zhi Zachary, Qiao, Yuchen, Li, Pingwei, Xu, Shiqing, Liu, Wenshe Ray

Volltext

A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals von Alugubelli, Yugendar R., Geng, Zhi Zachary, Yang, Kai S., Shaabani, Namir, Khatua, Kaustav, Ma, Xinyu R., Vatansever, Erol C., Cho, Chia-Chuan, Ma, Yuying, Xiao, Jing, Blankenship, Lauren R., Yu, Ge, Sankaran, Banumathi, Li, Pingwei, Allen, Robert, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray

Volltext

A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals von Ma, Yuying, Yang, Kai S., Geng, Zhi Zachary, Alugubelli, Yugendar R., Shaabani, Namir, Vatansever, Erol C., Ma, Xinyu R., Cho, Chia-Chuan, Khatua, Kaustav, Xiao, Jing, Blankenship, Lauren R., Yu, Ge, Sankaran, Banumathi, Li, Pingwei, Allen, Robert, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray

Volltext

An optimal “Click” formulation strategy for antibody-drug conjugate synthesis von Vatansever, Erol C., Kang, Jeffrey, Tuley, Alfred, Ward, E. Sally, Liu, Wenshe Ray

Volltext

Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells von Chen, Walter W, Birsoy, Kivanc, Mihaylova, Maria M, Snitkin, Harriet, Stasinski, Iwona, Yucel, Burcu, Bayraktar, Erol C, Carette, Jan E, Clish, Clary B, Brummelkamp, Thijn R, Sabatini, David D, Sabatini, David M

Volltext

A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV‑2 Main Protease von Geng, Zhi Zachary, Atla, Sandeep, Shaabani, Namir, Vulupala, Veerabhadra, Yang, Kai S., Alugubelli, Yugendar R., Khatua, Kaustav, Chen, Peng-Hsun, Xiao, Jing, Blankenship, Lauren R., Ma, Xinyu R., Vatansever, Erol C., Cho, Chia-Chuan D., Ma, Yuying, Allen, Robert, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray

Volltext

Evaluation of SARS-CoV‑2 Main Protease Inhibitors Using a Novel Cell-Based Assay von Cao, Wenyue, Cho, Chia-Chuan Dean, Geng, Zhi Zachary, Shaabani, Namir, Ma, Xinyu R, Vatansever, Erol C, Alugubelli, Yugendar R, Ma, Yuying, Chaki, Sankar P, Ellenburg, William H, Yang, Kai S, Qiao, Yuchen, Allen, Robert, Neuman, Benjamin W, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray

Volltext

A Genetically Encoded Allysine for the Synthesis of Proteins with Site‐Specific Lysine Dimethylation von Wang, Zhipeng A., Zeng, Yu, Kurra, Yadagiri, Wang, Xin, Tharp, Jeffery M., Vatansever, Erol C., Hsu, Willie W., Dai, Susie, Fang, Xinqiang, Liu, Wenshe R.

Volltext

Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors von Khatua, Kaustav, Alugubelli, Yugendar R., Yang, Kai S., Vulupala, Veerabhadra R., Blankenship, Lauren R., Coleman, Demonta, Atla, Sandeep, Chaki, Sankar P., Geng, Zhi Zachary, Ma, Xinyu R., Xiao, Jing, Chen, Peng-Hsun, Cho, Chia-Chuan D., Sharma, Shivangi, Vatansever, Erol C., Ma, Yuying, Yu, Ge, Neuman, Benjamin W., Xu, Shiqing, Liu, Wenshe Ray

Volltext