Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice von Singh, Gagandeep, García-Bernalt Diego, Juan, Warang, Prajakta, Park, Seok-Chan, Chang, Lauren A., Noureddine, Moataz, Laghlali, Gabriel, Bykov, Yonina, Prellberg, Matthew, Yan, Vivian, Singh, Sarabjot, Pache, Lars, Cuadrado-Castano, Sara, Webb, Brett, García-Sastre, Adolfo, Schotsaert, Michael

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Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade von Ghosh, Arnab, Michels, Judith, Mezzadra, Riccardo, Venkatesh, Divya, Dong, Lauren, Gomez, Ricardo, Samaan, Fadi, Ho, Yu-Jui, Campesato, Luis Felipe, Mangarin, Levi, Fak, John, Suek, Nathan, Holland, Aliya, Liu, Cailian, Abu-Akeel, Mohsen, Bykov, Yonina, Zhong, Hong, Fitzgerald, Kelly, Budhu, Sadna, Chow, Andrew, Zappasodi, Roberta, Panageas, Katherine S, de Henau, Olivier, Ruscetti, Marcus, Lowe, Scott W, Merghoub, Taha, Wolchok, Jedd D

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Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary von Kim, Sarah H., Da Cruz Paula, Arnaud, Basili, Thais, Dopeso, Higinio, Bi, Rui, Pareja, Fresia, da Silva, Edaise M., Gularte-Mérida, Rodrigo, Sun, Zhen, Fujisawa, Sho, Smith, Caitlin G., Ferrando, Lorenzo, Martins Sebastião, Ana Paula, Bykov, Yonina, Li, Anqi, Silveira, Catarina, Ashley, Charles W., Stylianou, Anthe, Selenica, Pier, Samore, Wesley R., Jungbluth, Achim A., Zamarin, Dmitriy, Abu-Rustum, Nadeem R., Helin, Kristian, Soslow, Robert A., Reis-Filho, Jorge S., Oliva, Esther, Weigelt, Britta

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Virus, Vessel, Victory: A Novel Approach to Tumor Killing von Bykov, Yonina, Zamarin, Dmitriy

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524 Tim-4+ resident macrophages impair anti-tumor immunity in the serous body cavities By sequestering viable and cytotoxic CD8+ T cells expressing high levels of phosphatidylserin... von Chow, Andrew, Schad, Sara, Green, Michael, Hellmann, Matthew, Ceglia, Nicholas, Allaj, Viola, Zago, Giulia, Shah, Nisarg, Sharma, Sai, Mattar, Marissa, Chan, Joseph, Rizvi, Hira, Zhong, Hong, Liu, Cailian, Bykov, Yonina, Zamarin, Dmitriy, Shi, Hongyu, Budhu, Sadna, Wohlhieter, Corrin, Uddin, Fathema, Gupta, Aditi, Khodos, Inna, Waninger, Jessica, Qin, Angel, Balachandran, Vinod, Zou, Weiping, Shah, Sohrab, McPherson, Andrew, Panageas, Katherine, Lewis, Jason, Perry, Justin, Stanchina, Elisa de, Sen, Triparna, Poirier, John, Wolchok, Jedd, Rudin, Charles, Merghoub, Taha

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Avian paramyxovirus 4 has potent antitumor activity that surpasses the oncolytic effect of NDV in colon carcinoma and melanoma in vivo models von Bykov, Yonina, Javaheri, Aryana, Mena, Ignacio, Garcia-Sastre, Adolfo, Cuadrado-Castano, Sara

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Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity von Chow, Andrew, Schad, Sara, Green, Michael D., Hellmann, Matthew D., Allaj, Viola, Ceglia, Nicholas, Zago, Giulia, Shah, Nisargbhai S., Sharma, Sai Kiran, Mattar, Marissa, Chan, Joseph, Rizvi, Hira, Zhong, Hong, Liu, Cailian, Bykov, Yonina, Zamarin, Dmitriy, Shi, Hongyu, Budhu, Sadna, Wohlhieter, Corrin, Uddin, Fathema, Gupta, Aditi, Khodos, Inna, Waninger, Jessica J., Qin, Angel, Markowitz, Geoffrey J., Mittal, Vivek, Balachandran, Vinod, Durham, Jennifer N., Le, Dung T., Zou, Weiping, Shah, Sohrab P., McPherson, Andrew, Panageas, Katherine, Lewis, Jason S., Perry, Justin S.A., de Stanchina, Elisa, Sen, Triparna, Poirier, John T., Wolchok, Jedd D., Rudin, Charles M., Merghoub, Taha

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Preclinical studies of the anti-tumor effects of novel Avian paramyxovirus 4 (APMV-4) oncolytic viral therapy combined with vascular endothelial growth factor-C (VEGF-C) in melanom... von Fernandez-Rodriguez, Ruben, Cuadrado-Castano, Sara, Javaheri, Aryana, Bykov, Yonina, Edwards, Andrew, Mena, Ignacio, Dasilva-Freire, Noelia, Rogic, Anita, Kamphorst, Alice O., Karlic, Rosa, Horowitz, Amir, García-Sastre, Adolfo, Skobe, Mihaela

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Preparation of single cells from tumors for single-cell RNA sequencing von Bykov, Yonina, Kim, Sarah H, Zamarin, Dmitriy

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Avian Paramyxovirus 4 Antitumor Activity Leads to Complete Remissions and Long-term Protective Memory in Preclinical Melanoma and Colon Carcinoma Models von Javaheri, Aryana, Bykov, Yonina, Mena, Ignacio, García-Sastre, Adolfo, Cuadrado-Castano, Sara

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Immune responses elicited by ssRNA(−) oncolytic viruses in the host and in the tumor microenvironment von Bykov, Yonina, Dawodu, Gloria, Javaheri, Aryana, Garcia-Sastre, Adolfo, Cuadrado-Castano, Sara

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Phase I/II study to evaluate systemic durvalumab + intraperitoneal (IP) ONCOS-102 in patients with peritoneal disease who have epithelial ovarian (OC) or metastatic colorectal canc... von Zamarin, Dmitriy, Odunsi, Kunle, Slomovitz, Brian M., Duska, Linda R., Nemunaitis, John J., Reilley, Matthew, Bykov, Yonina, Holland, Aliya, Hubbard-Lucey, Vanessa M., Shohara, Lisa, Schwarzenberger, Paul, Ricciardi, Toni, Macri, Mary J., Ryan, Aileen, Jaderberg, Magnus Erik, Venhaus, Ralph Rudolph

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Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy von Jiménez-Sánchez, Alejandro, Cybulska, Paulina, Mager, Katherine LaVigne, Koplev, Simon, Cast, Oliver, Couturier, Dominique-Laurent, Memon, Danish, Selenica, Pier, Nikolovski, Ines, Mazaheri, Yousef, Bykov, Yonina, Geyer, Felipe C., Macintyre, Geoff, Gavarró, Lena Morrill, Drews, Ruben M., Gill, Michael B., Papanastasiou, Anastasios D., Sosa, Ramon E., Soslow, Robert A., Walther, Tyler, Shen, Ronglai, Chi, Dennis S., Park, Kay J., Hollmann, Travis, Reis-Filho, Jorge S., Markowetz, Florian, Beltrao, Pedro, Vargas, Hebert Alberto, Zamarin, Dmitriy, Brenton, James D., Snyder, Alexandra, Weigelt, Britta, Sala, Evis, Miller, Martin L.

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Abstract 5217: Defining the balance of anti-viral and anti-tumor T cell responses to oncolytic virus therapy using single cell approaches von Burman, Bharat, Ceglia, Nicholas, Hirschhorn, Daniel, Budhu, Sadna, Mangarin, Levi, Oseledchyk, Anton, Bykov, Yonina, McPherson, Andrew, Shah, Sohrab, Wolchok, Jedd, Merghoub, Taha, Zamarin, Dmitriy

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Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity von Brodeur, Melica Nourmoussavi, Dopeso, Higinio, Zhu, Yingjie, Longhini, Ana Leda F, Gazzo, Andrea, Sun, Siyu, Koche, Richard P, Qu, Rui, Rosenberg, Laura, Hamard, Pierre-Jacques, Bykov, Yonina, Green, Hunter, Gusain, Laxmi, Chiappinelli, Katherine B, Ozsoy, Melih Arda, Chui, M Herman, Basili, Thais, Gardner, Rui, Walderich, Sven, DeStanchina, Elisa, Greenbaum, Benjamin, Gönen, Mithat, Vabret, Nicolas, Weigelt, Britta, Zamarin, Dmitriy

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Abstract 2553: Immune and malignant cell phenotypes of ovarian cancer are determined by distinct mutational processes von Vázquez-García, Ignacio, Uhlitz, Florian, Ceglia, Nicholas, Lim, Jamie L., Wu, Michelle, Mohibullah, Neeman, Ruiz, Arvin Eric B., Boehm, Kevin M., Bojilova, Viktoria, Fong, Christopher J., Funnell, Tyler, Grewal, Diljot, Havasov, Eliyahu, Leung, Samantha, Pasha, Arfath, Patel, Druv M., Pourmaleki, Maryam, Rusk, Nicole, Shi, Hongyu, Vanguri, Rami, Williams, Marc J., Zhang, Allen W., Broach, Vance, Chi, Dennis S., Paula, Arnaud Da Cruz, Gardner, Ginger J., Kim, Sarah H., Lennon, Matthew, Roche, Kara Long, Sonoda, Yukio, Zivanovic, Oliver, Kundra, Ritika, Viale, Agnes, Bykov, Yonina, Derakhshan, Fatemeh N., Geneslaw, Luke, Maroldi, Ana, Schietinger, Andrea, Hollmann, Travis J., Bakhoum, Samuel F., Soslow, Robert A., Ellenson, Lora H., Abu-Rustum, Nadeem, Aghajanian, Carol, Friedman, Claire F., McPherson, Andrew, Weigelt, Britta, Zamarin, Dmitriy, Shah, Sohrab P.

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Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy von Jiménez-Sánchez, Alejandro, Cybulska, Paulina, Mager, Katherine LaVigne, Koplev, Simon, Cast, Oliver, Couturier, Dominique-Laurent, Memon, Danish, Selenica, Pier, Nikolovski, Ines, Mazaheri, Yousef, Bykov, Yonina, Geyer, Felipe C, Macintyre, Geoff, Gavarró, Lena Morrill, Drews, Ruben M, Gill, Michael B, Papanastasiou, Anastasios D, Sosa, Ramon E, Soslow, Robert A, Walther, Tyler, Shen, Ronglai, Chi, Dennis S, Park, Kay J, Hollmann, Travis, Reis-Filho, Jorge S, Markowetz, Florian, Beltrao, Pedro, Vargas, Hebert Alberto, Zamarin, Dmitriy, Brenton, James D, Snyder, Alexandra, Weigelt, Britta, Sala, Evis, Miller, Martin L

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Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade von Ghosh, Arnab, Michels, Judith, Mezzadra, Riccardo, Venkatesh, Divya, Dong, Lauren, Gomez, Ricardo, Samaan, Fadi, Ho, Yu-Jui, Campesato, Luis Felipe, Mangarin, Levi, Fak, John, Suek, Nathan, Holland, Aliya, Liu, Cailian, Abu-Akeel, Mohsen, Bykov, Yonina, Zhong, Hong, Fitzgerald, Kelly, Budhu, Sadna, Chow, Andrew, Zappasodi, Roberta, Panageas, Katherine S, de Henau, Olivier, Ruscetti, Marcus, Lowe, Scott W, Merghoub, Taha, Wolchok, Jedd D

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Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade von Ghosh, Arnab, Michels, Judith, Mezzadra, Riccardo, Venkatesh, Divya, Dong, Lauren, Gomez, Ricardo, Samaan, Fadi, Ho, Yu-Jui, Campesato, Luis Felipe, Mangarin, Levi, Fak, John, Suek, Nathan, Holland, Aliya, Liu, Cailian, Abu-Akeel, Mohsen, Bykov, Yonina, Zhong, Hong, Fitzgerald, Kelly, Budhu, Sadna, Chow, Andrew, Zappasodi, Roberta, Panageas, Katherine S, de Henau, Olivier, Ruscetti, Marcus, Lowe, Scott W, Merghoub, Taha, Wolchok, Jedd D

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