Proteases, cystic fibrosis and the epithelial sodium channel (ENaC) von Thibodeau, P. H, Butterworth, M. B

Volltext

PKA-dependent ENaC trafficking requires the SNARE-binding protein complexin von Butterworth, M B, Frizzell, R A, Johnson, J P, Peters, K W, Edinger, R S

Volltext

cAMP-sensitive endocytic trafficking in A6 epithelia von Butterworth, Michael B, Helman, Sandy I, Els, Willem J

Volltext

PKA-dependent ENaC trafficking requires the SNARE-binding protein complexin von BUTTERWORTH, M. B, FRIZZELL, R. A, JOHNSON, J. P, PETERS, K. W, EDINGER, R. S

Volltext

Cytochemical localization of adenylate cyclase in cultured renal epithelial (A6) cells von Els, Willem J., Butterworth, Michael B.

Volltext

Cysteine String Protein Monitors Late Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis von Zhang, Hui, Schmidt, Bela Z., Sun, Fei, Condliffe, Steven B., Butterworth, Michael B., Youker, Robert T., Brodsky, Jeffrey L., Aridor, Meir, Frizzell, Raymond A.

Volltext

Testing new physics models with global comparisons to collider measurements: the Contur toolkit von Buckley, Andy, Butterworth, Jonathan, Corpe, Louie, Habedank, Martin, Huang, Danping, Yallup, David, Altakach, M., Bassman, G., Lagwankar, Ishaan, Rocamonde, Juan, Saunders, H., Waugh, B., Zilgalvis, G.

Volltext

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies von Kaptoge, Stephen, Butterworth, Adam S, Willeit, Peter, Bolton, Thomas, Paige, Ellie, Paul, Dirk S, Bell, Steven, Astle, William, Verschuren, W M Monique, Sato, Shinichi, Njølstad, Inger, Salomaa, Veikko, Yeap, Bu B, Melander, Olle, Marmot, Michael, Dahm, Christina C, Dale, Caroline E, van der Schouw, Yvonne T, Simons, Leon A, Schoufour, Josje D, Key, Timothy J, Moreno-Iribas, Conchi, Davidson, Karina W, Taylor, James O, Wallace, Robert B, Tumino, Rosario, Linneberg, Allan, Panico, Salvatore, Nietert, Paul J, Kromhout, Daan, Kiechl, Stefan, Palli, Domenico, Huerta, José M, Karakatsani, Anna, Kühn, Tilman, Grobbee, Diederick E, Kauhanen, Jussi, Wennberg, Maria, Cushman, Mary, Cooper, Jackie A, Rodriguez, Carlos J, Shaw, Jonathan E, Voortman, Trudy, Dallongeville, Jean, Brunner, Eric J, Lazo, Mariana, Leon, David A, Smith, George Davey, Peto, Richard, Jackson, Rod, Banks, Emily, Butterworth, Adam, Warnakula, Samantha, Paige, Ellie, Bell, Steven, Astle, William, Sato, Shinichi, Veikko, Salomaa, Flecther, Astrid, Melander, Olle, Kuller, Lewis H, Koenig, Wolfgang, Casiglia, Edoardo, Arndt, Volker, Völzke, Henry, Dahm, Christina C, Dale, Caroline E, Bergmann, Manuela, Crespo, Carlos, Kaaks, Rudolf, Simons, Leon A, Lagiou, Pagona, Key, Timothy J, Rodriguez, Beatriz, Moreno-Iribas, Conchi, Davidson, Karina W, Quiros, J. Ramon, Skeie, Guri, Salomaa, Veikko, Strandberg, Timo, Nietert, Paul J, Salamanca-Fernandez, Elena, Krumholz, Harlan M, Price, Jackie, Travis, Ruth C, Kühn, Tilman, Barrett-Connor, Elizabeth, van Schoor, Natasja, Boeing, Heiner, Overvad, Kim, Kauhanen, Jussi, Forouhi, Nita, Wennberg, Maria, Brenner, Hermann, Assmann, Gerd, Trevisan, Maurizio, Gillumn, Richard F, Thompson, Simon, Ferrari, Pietro, Davey Smith, George

Volltext

Collider constraints on Z′ models for neutral current B-anomalies von Allanach, B. C., Butterworth, J. M., Corbett, Tyler

Volltext

Mendelian Randomization Study of ACLY and Cardiovascular Disease von Ference, Brian A, Ray, Kausik K, Catapano, Alberico L, Ference, Thatcher B, Burgess, Stephen, Neff, David R, Oliver-Williams, Clare, Wood, Angela M, Butterworth, Adam S, Di Angelantonio, Emanuele, Danesh, John, Kastelein, John J.P, Nicholls, Stephen J

Volltext

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci von Stacey, David, Fauman, Eric B, Ziemek, Daniel, Sun, Benjamin B, Harshfield, Eric L, Wood, Angela M, Butterworth, Adam S, Suhre, Karsten, Paul, Dirk S

Volltext

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases von Zheng, Jie, Haberland, Valeriia, Baird, Denis, Walker, Venexia, Haycock, Philip C., Hurle, Mark R., Gutteridge, Alex, Erola, Pau, Liu, Yi, Luo, Shan, Robinson, Jamie, Richardson, Tom G., Staley, James R., Elsworth, Benjamin, Burgess, Stephen, Sun, Benjamin B., Danesh, John, Runz, Heiko, Maranville, Joseph C., Martin, Hannah M., Yarmolinsky, James, Laurin, Charles, Holmes, Michael V., Liu, Jimmy Z., Estrada, Karol, Santos, Rita, McCarthy, Linda, Waterworth, Dawn, Nelson, Matthew R., Smith, George Davey, Butterworth, Adam S., Hemani, Gibran, Scott, Robert A., Gaunt, Tom R.

Volltext

Cell-Specific Radiosensitization by Gold Nanoparticles at Megavoltage Radiation Energies von Jain, Suneil, M.B., B.Ch, Coulter, Jonathan A., Ph.D, Hounsell, Alan R., Ph.D, Butterworth, Karl T., Ph.D, McMahon, Stephen J., Ph.D, Hyland, Wendy B., B.Sc. Hons, Muir, Mark F., B.Sc, Dickson, Glenn R., Ph.D, Prise, Kevin M., Ph.D, Currell, Fred J., Ph.D, O’Sullivan, Joe M., M.D, Hirst, David G., Ph.D

Volltext

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases von Ferreira, Ricardo C, Freitag, Daniel F, Cutler, Antony J, Howson, Joanna M M, Rainbow, Daniel B, Smyth, Deborah J, Kaptoge, Stephen, Clarke, Pamela, Boreham, Charlotte, Coulson, Richard M, Pekalski, Marcin L, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S, Butterworth, Adam S, Malarstig, Anders, Danesh, John, Todd, John A

Volltext

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes von Chauhan, Ganesh, Traylor, Matthew, Sargurupremraj, Muralidharan, Okada, Yukinori, Mishra, Aniket, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig, Anderson, Christopher D., Almgren, Peter, Amouyel, Philippe, Bartz, Traci M., Benavente, Oscar R., Boncoraglio, Giorgio B., Butterworth, Adam S., Carrera, Caty, Chasman, Daniel I., Cotlarciuc, Ioana, Cruchaga, Carlos, de Bakker, Paul I. W., Duan, Qing, Gottesman, Rebecca F., Harris, Tamara B., Hassan, Ahamad, Havulinna, Aki S., Heckbert, Susan R., Hyacinth, Hyacinth I., Ikram, M. Arfan, Ingelsson, Erik, Jian, Xueqiu, Jukema, J. Wouter, Kanai, Masahiro, Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Kooperberg, Charles, Lange, Leslie A., Langenberg, Claudia, Launer, Lenore J., Lemmens, Robin, Lewis, Cathryn M., Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K., Meschia, James F., Mitchell, Braxton D., Mosley, Thomas H., Nalls, Michael A., O’Donnell, Martin J., Pulit, Sara L., Reiner, Alexander P., Ridker, Paul M., Rothwell, Peter M., Rotter, Jerome I., Sale, Michele M., Salomaa, Veikko, Sapkota, Bishwa R., Schmidt, Reinhold, Schmidt, Carsten O., Sharma, Pankaj, Slowik, Agnieszka, Sudlow, Cathie L. M., Tanislav, Christian, Thijs, Vincent N. S., Thorsteinsdottir, Unnur, Tiedt, Steffen, Trompet, Stella, Wareham, Nicholas J., Wassertheil-Smoller, Sylvia, Wilson, James G., Pastinen, Tomi, Ruusalepp, Arno, Koplev, Simon, Björkegren, Johan L. M., Codoni, Veronica, Civelek, Mete, Christophersen, Ingrid E., Roselli, Carolina, Ellinor, Patrick T., Kato, Norihiro, van der Harst, Pim, Elliott, Paul, Takeuchi, Fumihiko, Johnson, Andrew D., Sanghera, Dharambir K., Melander, Olle, Strbian, Daniel, Fernandez-Cadenas, Israel, Rolfs, Arndt, Hata, Jun, Woo, Daniel, Pare, Guillaume, Hopewell, Jemma C., Saleheen, Danish, Stefansson, Kari, Worrall, Bradford B., Seshadri, Sudha, Markus, Hugh S., Debette, Stephanie, Dichgans, Martin

Volltext

Assessing the causal association of glycine with risk of cardio-metabolic diseases von Wittemans, Laura B. L., Lotta, Luca A., Oliver-Williams, Clare, Stewart, Isobel D., Surendran, Praveen, Karthikeyan, Savita, Day, Felix R., Koulman, Albert, Imamura, Fumiaki, Zeng, Lingyao, Erdmann, Jeanette, Schunkert, Heribert, Khaw, Kay-Tee, Griffin, Julian L., Forouhi, Nita G., Scott, Robert A., Wood, Angela M., Burgess, Stephen, Howson, Joanna M. M., Danesh, John, Wareham, Nicholas J., Butterworth, Adam S., Langenberg, Claudia

Volltext

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits von Mifsud, Borbala, Witkowska, Katarzyna, Tzanis, Evan, Velez Edwards, Digna R., Wilson, Peter W. F., Esko, Tonu, Almgren, Peter, Debette, Stéphanie, Li-Gao, Ruifang, Qian, Yong, Sargurupremraj, Muralidharan, Thériault, Sébastien, Verweij, Niek, Zhao, Jing-Hua, de Mutsert, Renée, Menni, Cristina, Paré, Guillaume, Poulter, Neil R., Ayers, Kristin L., Barbieri, Caterina M., Bis, Joshua C., Bochud, Murielle, Boomsma, Dorret I., Bottinger, Erwin P., Brumat, Marco, Campbell, Harry, Chakravarti, Aravinda, Ciullo, Marina, Cordell, Heather J., Davies, Gail, de Geus, Eco J., Deary, Ian J., Ehret, Georg B., Ferreira, Teresa, Franco, Oscar H., Gandin, Ilaria, Gasparini, Paolo, Goel, Anuj, Gow, Alan J., Gyllensten, Ulf, Harris, Sarah E., Hicks, Andrew A., Hofman, Albert, Hwang, Shih-Jen, James, Alan, Johansson, Åsa, Jukema, J. Wouter, Kähönen, Mika, Khaw, Kay-Tee, Knekt, Paul, Knight, Joanne, Launer, Lenore J., Lehne, Benjamin, Liewald, David C. M., Lind, Lars, Liu, YongMei, Lopez, Lorna M., Lyytikäinen, Leo-Pekka, Marten, Jonathan, Morris, Andrew P., Nandakumar, Priyanka, Nolte, Ilja M., Nutile, Teresa, Oostra, Ben A., Padmanabhan, Sandosh, Penninx, Brenda W. J. H., Perola, Markus, Peters, Annette, Pramstaller, Peter P., Nguyen, Quang Tri, Raitakari, Olli T., Ren, Meixia, Rettig, Rainer, Ridker, Paul M., Ried, Janina S., Riese, Harriëtte, Rotter, Jerome I., Rudan, Igor, Salomaa, Veikko, Smith, Albert V., Snieder, Harold, Sõber, Siim, Teumer, Alexander, Tomaszewski, Maciej, Toniolo, Daniela, Trompet, Stella, Tuomilehto, Jaakko, Vaez, Ahmad, van Duijn, Cornelia M., Vuckovic, Dragana, Wilson, James F., Yao, Jie, Zhang, Weihua, Attia, John R., Howson, Joanna M. M., O’Donnell, Christopher J., Edwards, Todd L., Psaty, Bruce M., Tzoulaki, Ioanna, Elliott, Paul

Volltext

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease von Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.

Volltext

Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation von Kaptoge, S, Seshasai, SRK, Burgess, S, Pennells, L, Altay, S, Assmann, G, Björkelund, C, Brunner, EJ, Dagenais, GR, Cushman, M, D'Agostino, RB, Daniels, LB, Donfrancesco, C, Ducimetiere, P, Elders, PJM, Engström, G, Gallacher, I, de La Cámara, G, Gudnason, V, Hansson, PO, Imano, H, Jukema, JW, Kauhanen, J, Krumholz, HM, Meyer, HE, Nietert, PJ, Price, JF, Ridker, PM, Sun, Q, Verschuren, WMM, Völzke, H, Wallace, RB, Yamagishi, K, Griffin, S, Butterworth, AS, Sattar, N, Bancks, MP, Mongraw-Chaffin, M, Magliano, D, Whincup, PH, Leitner, C, Lawlor, DA, Sutherland, SE, Hunt, KJ, Selmer, RM, Haheim, LL, Ariansen, I, Tybjaer-Hansen, A, Frikkle-Schmidt, R, Lo Noce, C, Balkau, B, Bonnet, F, Khaw, KT, Nissinen, A, Vartiainen, E, Pencina, M, Susa, S, Roth, J, Lissner, L, Hange, D, Tilvis, RS, Norman, PE, Almeida, OP, Hankey, GJ, Hata, J, Kraft, P, Turman, C, Kiyama, M, Kitamura, A, Salonen, JT, van Schoor, LN, Melander, O, Psaty, BM, Kronmal, RA, Grandits, G, Gillum, RF, Hu, FB, Humphries, S, Hill- Briggs, F, Vrany, E, Schwartz, JE, Iso, H, Amouyel, P, Arveiler, D, Ferrieres, J, Gansevoort, RT, de Boer, R, Lamarche, B, Thorsson, B, Sigurdsson, G, Ikram, MA, Fretts, AM, Ali, T, Can, G, Yüksel, H, Özkan, U, Buring, J, Tinker, L, Shipley, M, Packard, C

Volltext

Increased Cell Proliferation and Neurogenesis in the Adult Human Huntington's Disease Brain von Curtis, Maurice A., Penney, Ellen B., Pearson, Andree G., Willeke M. C. van Roon-Mom, Butterworth, Niqi J., Dragunow, Michael, Connor, Bronwen, Richard L. M. Faull

Volltext