Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses von Butters, Terry D, Dwek, Raymond A, Platt, Frances M

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A Systematic Investigation of Iminosugar Click Clusters as Pharmacological Chaperones for the Treatment of Gaucher Disease von Joosten, Antoine, Decroocq, Camille, de Sousa, Julien, Schneider, Jérémy P., Etamé, Emile, Bodlenner, Anne, Butters, Terry D., Compain, Philippe

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Polyhydroxylated Bicyclic Isoureas and Guanidines Are Potent Glucocerebrosidase Inhibitors and Nanomolar Enzyme Activity Enhancers in Gaucher Cells von Trapero, Ana, Alfonso, Ignacio, Butters, Terry D, Llebaria, Amadeu

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Potent Aminocyclitol Glucocerebrosidase Inhibitors are Subnanomolar Pharmacological Chaperones for Treating Gaucher Disease von Trapero, Ana, González-Bulnes, Patricia, Butters, Terry D, Llebaria, Amadeu

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Gangliosides play an important role in the organization of CD82-enriched microdomains von Odintsova, Elena, Butters, Terry D, Monti, Eugenio, Sprong, Hein, van Meer, Gerrit, Berditchevski, Fedor

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Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease von Ersek, Adel, Xu, Ke, Antonopoulos, Aristotelis, Butters, Terry D, Santo, Ana Espirito, Vattakuzhi, Youridies, Williams, Lynn M, Goudevenou, Katerina, Danks, Lynett, Freidin, Andrew, Spanoudakis, Emmanouil, Parry, Simon, Papaioannou, Maria, Hatjiharissi, Evdoxia, Chaidos, Aristeidis, Alonzi, Dominic S, Twigg, Gabriele, Hu, Ming, Dwek, Raymond A, Haslam, Stuart M, Roberts, Irene, Dell, Anne, Rahemtulla, Amin, Horwood, Nicole J, Karadimitris, Anastasios

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Targeting glycosylation as a therapeutic approach von Dwek, Raymond A, Butters, Terry D, Platt, Frances M, Zitzmann, Nicole

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Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase von Thompson, Andrew J, Williams, Rohan J, Hakki, Zalihe, Alonzi, Dominic S, Wennekes, Tom, Gloster, Tracey M, Songsrirote, Kriangsak, Thomas-Oates, Jane E, Wrodnigg, Tanja M, Spreitz, Josef, Stütz, Arnold E, Butters, Terry D, Williams, Spencer J, Davies, Gideon J

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Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells von Diot, Jennifer D, Moreno, Isabel Garcia, Twigg, Gabriele, Mellet, Carmen Ortiz, Haupt, Karsten, Butters, Terry D, Kovensky, José, Gouin, Sébastien G

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Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone von Zampieri, Stefania, Mellon, Synthia H., Butters, Terry D., Nevyjel, Marco, Covey, Douglas F., Bembi, Bruno, Dardis, Andrea

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Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals von Speak, Anneliese O, Salio, Mariolina, Neville, David C.A, Fontaine, Josette, Priestman, David A, Platt, Nick, Heare, Tanya, Butters, Terry D, Dwek, Raymond A, Trottein, Francois, Exley, Mark A, Cerundolo, Vincenzo, Platt, Frances M

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Inhibition of Glycosphingolipid Biosynthesis:  Application to Lysosomal Storage Disorders von Butters, Terry D, Dwek, Raymond A, Platt, Frances M

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Pharmacotherapeutic strategies using small molecules for the treatment of glycolipid lysosomal storage disorders von Butters, Terry D

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Rational Design and Synthesis of Highly Potent Pharmacological Chaperones for Treatment of N370S Mutant Gaucher Disease von Wang, Guan-Nan, Reinkensmeier, Gabriele, Zhang, Si-Wei, Zhou, Jian, Zhang, Liang-Ren, Zhang, Li-He, Butters, Terry D, Ye, Xin-Shan

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Adduction of Cholesterol 5,6-Secosterol Aldehyde to Membrane-Bound Myelin Basic Protein Exposes an Immunodominant Epitope von Cygan, Natalie K, Scheinost, Johanna C, Butters, Terry D, Wentworth, Paul

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Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition von Glawar, Andreas F. G., Best, Daniel, Ayers, Benjamin J., Miyauchi, Saori, Nakagawa, Shinpei, Aguilar-Moncayo, Matilde, García Fernández, José M., Ortiz Mellet, Carmen, Crabtree, Elizabeth V., Butters, Terry D., Wilson, Francis X., Kato, Atsushi, Fleet, George W. J.

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Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition von Alonzi, Dominic S, Neville, David C A, Lachmann, Robin H, Dwek, Raymond A, Butters, Terry D

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Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins von Alonzi, Dominic S, Kukushkin, Nikolay V, Allman, Sarah A, Hakki, Zalihe, Williams, Spencer J, Pierce, Lorna, Dwek, Raymond A, Butters, Terry D

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Development of a Single Column Method for the Separation of Lipid- and Protein-Derived Oligosaccharides von Neville, David C. A, Dwek, Raymond A, Butters, Terry D

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Gaucher disease von Butters, Terry D

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