Ten years of pathway analysis: current approaches and outstanding challenges von Khatri, Purvesh, Sirota, Marina, Butte, Atul J

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Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study von Kather, Jakob Nikolas, Krisam, Johannes, Charoentong, Pornpimol, Luedde, Tom, Herpel, Esther, Weis, Cleo-Aron, Gaiser, Timo, Marx, Alexander, Valous, Nektarios A, Ferber, Dyke, Jansen, Lina, Reyes-Aldasoro, Constantino Carlos, Zörnig, Inka, Jäger, Dirk, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Halama, Niels

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Deep learning for lung cancer prognostication: A retrospective multi-cohort radiomics study von Hosny, Ahmed, Parmar, Chintan, Coroller, Thibaud P, Grossmann, Patrick, Zeleznik, Roman, Kumar, Avnish, Bussink, Johan, Gillies, Robert J, Mak, Raymond H, Aerts, Hugo J W L

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xCell: digitally portraying the tissue cellular heterogeneity landscape von Aran, Dvir, Hu, Zicheng, Butte, Atul J

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Leveraging big data to transform target selection and drug discovery von Chen, B, Butte, AJ

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Systematic pan-cancer analysis of tumour purity von Aran, Dvir, Sirota, Marina, Butte, Atul J.

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Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences von Brodin, Petter, Jojic, Vladimir, Gao, Tianxiang, Bhattacharya, Sanchita, Angel, Cesar J. Lopez, Furman, David, Shen-Orr, Shai, Dekker, Cornelia L., Swan, Gary E., Butte, Atul J., Maecker, Holden T., Davis, Mark M.

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Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses von Chiang, AP, Butte, AJ

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Prediction of myopia development among Chinese school-aged children using refraction data from electronic medical records: A retrospective, multicentre machine learning study von Lin, Haotian, Long, Erping, Ding, Xiaohu, Diao, Hongxing, Chen, Zicong, Liu, Runzhong, Huang, Jialing, Cai, Jingheng, Xu, Shuangjuan, Zhang, Xiayin, Wang, Dongni, Chen, Kexin, Yu, Tongyong, Wu, Dongxuan, Zhao, Xutu, Liu, Zhenzhen, Wu, Xiaohang, Jiang, Yuzhen, Yang, Xiao, Cui, Dongmei, Liu, Wenyan, Zheng, Yingfeng, Luo, Lixia, Wang, Haibo, Chan, Chi-Chao, Morgan, Ian G, He, Mingguang, Liu, Yizhi

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An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus von Patel, Chirag J, Bhattacharya, Jayanta, Butte, Atul J

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Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population von Comuzzie, Anthony G, Cole, Shelley A, Laston, Sandra L, Voruganti, V. Saroja, Haack, Karin, Gibbs, Richard A, Butte, Nancy F, Crawford, Dana C

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Comprehensive analysis of normal adjacent to tumor transcriptomes von Aran, Dvir, Camarda, Roman, Odegaard, Justin, Paik, Hyojung, Oskotsky, Boris, Krings, Gregor, Goga, Andrei, Sirota, Marina, Butte, Atul J.

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The Case for Algorithmic Stewardship for Artificial Intelligence and Machine Learning Technologies von Eaneff, Stephanie, Obermeyer, Ziad, Butte, Atul J

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Hybrid Models Based on Machine Learning and an Increasing Degree of Process Knowledge: Application to Capture Chromatographic Step von Narayanan, Harini, Luna, Martin, Sokolov, Michael, Arosio, Paolo, Butté, Alessandro, Morbidelli, Massimo

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Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels von Nam, Sungmin, Hu, Kenneth H., Butte, Manish J., Chaudhuri, Ovijit

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Machine Learning for Biologics: Opportunities for Protein Engineering, Developability, and Formulation von Narayanan, Harini, Dingfelder, Fabian, Butté, Alessandro, Lorenzen, Nikolai, Sokolov, Michael, Arosio, Paolo

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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage von Aran, Dvir, Looney, Agnieszka P., Liu, Leqian, Wu, Esther, Fong, Valerie, Hsu, Austin, Chak, Suzanna, Naikawadi, Ram P., Wolters, Paul J., Abate, Adam R., Butte, Atul J., Bhattacharya, Mallar

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A new generation of predictive models: The added value of hybrid models for manufacturing processes of therapeutic proteins von Narayanan, Harini, Sokolov, Michael, Morbidelli, Massimo, Butté, Alessandro

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Prototype of running clinical trials in an untrustworthy environment using blockchain von Wong, Daniel R., Bhattacharya, Sanchita, Butte, Atul J.

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GaN surface as the source of non-radiative defects in InGaN/GaN quantum wells von Haller, C., Carlin, J.-F., Jacopin, G., Liu, W., Martin, D., Butté, R., Grandjean, N.

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