The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets von Burns, Julie E., Hurst, Carolyn D., Knowles, Margaret A., Phillips, Roger M., Allison, Simon J.

Volltext

Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors von Hafner, Christian, Toll, Agustí, Fernández-Casado, Alejandro, Earl, Julie, Marqués, Miriam, Acquadro, Francesco, Méndez-Pertuz, Marinela, Urioste, Miguel, Malats, Núria, Burns, Julie E., Knowles, Margaret A., Cigudosa, Juan C., Hartmann, Arndt, Vogt, Thomas, Landthaler, Michael, Pujol, Ramón M., Real, Francisco X., Vogt, Peter K.

Volltext

Evaluating baculovirus as a vector for human prostate cancer gene therapy von Swift, Stephanie L, Rivera, Guillermo C, Dussupt, Vincent, Leadley, Regina M, Hudson, Lucy C, Ma de Ridder, Corrina, Kraaij, Robert, Burns, Julie E, Maitland, Norman J, Georgopoulos, Lindsay J

Volltext

Identification of mutations in distinct regions of p85 alpha in urothelial cancer von Ross, Rebecca L, Burns, Julie E, Taylor, Claire F, Mellor, Paul, Anderson, Deborah H, Knowles, Margaret A

Volltext

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency von Hurst, Carolyn D., Alder, Olivia, Platt, Fiona M., Droop, Alastair, Stead, Lucy F., Burns, Julie E., Burghel, George J., Jain, Sunjay, Klimczak, Leszek J., Lindsay, Helen, Roulson, Jo-An, Taylor, Claire F., Thygesen, Helene, Cameron, Angus J., Ridley, Anne J., Mott, Helen R., Gordenin, Dmitry A., Knowles, Margaret A.

Volltext

Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling von Hurst, Carolyn D, Cheng, Guo, Platt, Fiona M, Alder, Olivia, Black, Emma VI, Burns, Julie E, Brown, Joanne, Jain, Sunjay, Roulson, Jo‐An, Knowles, Margaret A

Volltext

From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor von Turner, Lewis D, Trinh, Chi H, Hubball, Ryan A, Orritt, Kyle M, Lin, Chi-Chuan, Burns, Julie E, Knowles, Margaret A, Fishwick, Colin W. G

Volltext

Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro von Pettitt, Geoffrey A, Hurst, Carolyn D, Khan, Zubeda, McPherson, Helen R, Dunning, Matthew C, Alder, Olivia, Platt, Fiona M, Black, Emma VI, Burns, Julie E, Knowles, Margaret A

Volltext

An Internal Polyadenylation Signal Substantially Increases Expression Levels of Lentivirus-Delivered Transgenes but Has the Potential to Reduce Viral Titer in a Promoter-Dependent... von HAGER, Stefanie, FRAME, Fiona M, COLLINS, Anne T, BURNS, Julie E, MAITLAND, Norman J

Volltext

Dimerization of the Human Papillomavirus Type 16 E2 N Terminus Results in DNA Looping within the Upstream Regulatory Region von Hernandez-Ramon, Elena E, Burns, Julie E, Zhang, Wenke, Walker, Hannah F, Allen, Stephanie, Antson, Alfred A, Maitland, Norman J

Volltext

Altered Expression of Neurotensin Receptors Is Associated with the Differentiation State of Prostate Cancer von SWIFT, Stephanie L, BURNS, Julie E, MAITLAND, Norman J

Volltext

Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight von Hurst, Carolyn D., Cheng, Guo, Platt, Fiona M., Castro, Mauro A.A., Marzouka, Nour-al-dain S., Eriksson, Pontus, Black, Emma V.I., Alder, Olivia, Lawson, Andrew R.J., Lindskrog, Sia V., Burns, Julie E., Jain, Sunjay, Roulson, Jo-An, Brown, Joanne C., Koster, Jan, Robertson, A. Gordon, Martincorena, Inigo, Dyrskjøt, Lars, Höglund, Mattias, Knowles, Margaret A.

Volltext

Abstract LB-323: The genomic landscape of non-muscle-invasive bladder cancer: implications for molecular classification and treatment von Hurst, Carolyn D., Alder, Olivia, Platt, Fiona M., Droop, Alastair, Stead, Lucy F., Burns, Julie E., Burghel, George J., Jain, Sunjay, Klimczak, Leszek J., Lindsay, Helen, Roulson, Jo-An, Taylor, Claire F., Thygesen, Helene, Cameron, Angus J., Ridley, Anne J., Mott, Helene R., Gordenin, Dmitry A., Knowles, Margaret A.

Volltext

Phenotypic effects of HPV-16 E2 protein expression in human keratinocytes von Burns, Julie E, Walker, Hannah F, Schmitz, Christian, Maitland, Norman J

Volltext

Development and limitations of lentivirus vectors as tools for tracking differentiation in prostate epithelial cells von Frame, Fiona M., Hager, Stefanie, Pellacani, Davide, Stower, Mike J., Walker, Hannah F., Burns, Julie E., Collins, Anne T., Maitland, Norman J.

Volltext

Structure of the intact transactivation domain of the human papillomavirus E2 protein von Wilson, Keith S, Antson, Alfred A, Burns, Julie E, Moroz, Olga V, Scott, David J, Sanders, Cyril M, Bronstein, Igor B, Dodson, G. Guy, Maitland, Norman J

Volltext

Inverse relationship between the expression of the human papillomavirus type 16 transcription factor E2 and virus DNA copy number during the progression of cervical intraepithelial... von Stevenson, Mark, Hudson, Lucy C, Burns, Julie E, Stewart, Roy L, Wells, Michael, Maitland, Norman J

Volltext

Abstract 3145: Mechanisms of resistance to FGFR-targeted therapy in bladder cancer von Pettitt, Geoffrey A., McPherson, Helen R., Hurst, Carolyn D., Burns, Julie E., Alder, Olivia A., Dunning, Matthew C., Knowles, Margaret A.

Volltext

Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile, Clinical Outcome and Female Gender Bias in KDM6A Mutation Frequency von Hurst, Carolyn D., Alder, Olivia, Platt, Fiona M., Droop, Alastair, Stead, Lucy F., Burns, Julie E., Burghel, George J., Jain, Sunjay, Klimczak, Leszek J., Lindsay, Helen, Roulson, Jo-An, Taylor, Claire F., Thygesen, Helene, Cameron, Angus J., Ridley, Anne J., Mott, Helen R., Gordenin, Dmitry A., Knowles, Margaret A.

Volltext

Human papillomavirus type 16 E2-specific T-helper lymphocyte responses in patients with cervical intraepithelial neoplasia von Bontkes, Hetty J, de Gruijl, Tanja D, Bijl, Astrid, Verheijen, Rene H. M, Meijer, Chris J. L. M, Scheper, Rik J, Stern, Peter L, Burns, Julie E, Maitland, Norman J, Walboomers, Jan M. M

Volltext