Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans von Elbe, Annika, Foerster, Kathrin Isabelle, Blank, Antje, Rose, Peter, Burhenne, Jürgen, Haefeli, Walter Emil, Mikus, Gerd

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Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug–Drug Interactions with Potential Perpetrator Drugs von Mikus, Gerd, Foerster, Kathrin I., Schaumaeker, Marlene, Lehmann, Marie-Louise, Burhenne, Jürgen, Haefeli, Walter E.

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A Nanocarrier Approach for Oral Peptide Delivery: Evaluation of Cell‐Penetrating‐Peptide‐Modified Liposomal Formulations in Dogs von Uhl, Philipp, Bajraktari‐Sylejmani, Gzona, Witzigmann, Dominik, Bay, Cindy, Zimmermann, Stefan, Burhenne, Jürgen, Weiss, Johanna, Haefeli, Walter E., Sauter, Max

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Clinical feasibility of dried blood spots: Analytics, validation, and applications von Enderle, Yeliz, Foerster, Kathrin, Burhenne, Jürgen

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Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans von Hohmann, Nicolas, Reinhard, Raphael, Schnaidt, Sven, Witt, Lukas, Carls, Alexandra, Burhenne, Jürgen, Mikus, Gerd, Haefeli, Walter E

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The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype von Markert, Christoph, Kastner, Ida Maria, Hellwig, Regina, Kalafut, Peter, Schweizer, Yvonne, Hoffmann, Michael Marcus, Burhenne, Jürgen, Weiss, Johanna, Mikus, Gerd, Haefeli, Walter Emil

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Pre‐systemic Elimination of Tilidine: Localization and Consequences for the Formation of the Active Metabolite Nortilidine von Eichbaum, Christine, Mathes, Kristin, Burhenne, Jürgen, Markert, Christoph, Blank, Antje, Mikus, Gerd

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Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity von Stoll, Felicitas, Burhenne, Jürgen, Lausecker, Berthold, Weiss, Johanna, Thomsen, Torben, Haefeli, Walter Emil, Mikus, Gerd

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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression von Sadik, Ahmed, Somarribas Patterson, Luis F., Öztürk, Selcen, Mohapatra, Soumya R., Panitz, Verena, Secker, Philipp F., Pfänder, Pauline, Loth, Stefanie, Salem, Heba, Prentzell, Mirja Tamara, Berdel, Bianca, Iskar, Murat, Faessler, Erik, Reuter, Friederike, Kirst, Isabelle, Kalter, Verena, Foerster, Kathrin I., Jäger, Evelyn, Guevara, Carina Ramallo, Sobeh, Mansour, Hielscher, Thomas, Poschet, Gernot, Reinhardt, Annekathrin, Hassel, Jessica C., Zapatka, Marc, Hahn, Udo, von Deimling, Andreas, Hopf, Carsten, Schlichting, Rita, Escher, Beate I., Burhenne, Jürgen, Haefeli, Walter E., Ishaque, Naveed, Böhme, Alexander, Schäuble, Sascha, Thedieck, Kathrin, Trump, Saskia, Seiffert, Martina, Opitz, Christiane A.

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Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter-based drug-drug interactions von Clemens, Jannick, Welti, Lukas, Schäfer, Julia, Seckinger, Anja, Burhenne, Jürgen, Theile, Dirk, Weiss, Johanna

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Desorption/Ionization-MS Methods for Drug Quantification in Biological Matrices and Their Validation Following Regulatory Guidance von Fresnais, Margaux, Burhenne, Jürgen, Haefeli, Walter E, Longuespée, Rémi

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Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma von Gehrig, Anne-Kathrin, Mikus, Gerd, Haefeli, Walter E., Burhenne, Jürgen

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Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC–MS/MS-Based Assay von Foerster, Kathrin I, Huppertz, Andrea, Meid, Andreas D, Müller, Oliver J, Rizos, Timolaos, Tilemann, Lisa, Haefeli, Walter E, Burhenne, Jürgen

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Turquoise to dark green organs at autopsy von Warth, Arne, Goeppert, Benjamin, Bopp, Christian, Schirmacher, Peter, Flechtenmacher, Christa, Burhenne, Jürgen

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A Highly Sensitive UPLC-MS/MS Method for the Quantification of the Organic Cation Transporters' Mediated Metformin Uptake and Its Inhibition in Cells von Bajraktari-Sylejmani, Gzona, Bay, Cindy, Gebauer, Lukas, Burhenne, Jürgen, Weiss, Johanna, Sauter, Max

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Voriconazole Concentration in Human Aqueous Humor and Plasma during Topical or Combined Topical and Systemic Administration for Fungal Keratitis von THIEL, Michael A, ZINKERNAGEL, Annelies S, BURHENNE, Jürgen, KAUFMANN, Claude, HAEFELI, Walter E

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A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy von Wass, Maxi, Göllner, Stefanie, Besenbeck, Birgit, Schlenk, Richard F., Mundmann, Petra, Göthert, Joachim R., Noppeney, Richard, Schliemann, Christoph, Mikesch, Jan-Henrik, Lenz, Georg, Dugas, Martin, Wermke, Martin, Röllig, Christoph, Bornhäuser, Martin, Serve, Hubert, Platzbecker, Uwe, Foerster, Kathrin I., Burhenne, Jürgen, Haefeli, Walter E., Müller, Lutz P., Binder, Mascha, Pabst, Caroline, Müller-Tidow, Carsten

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Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease von Hohmann, Nicolas, Schröder, Fabian, Moreira, Bernardo, Teng, Haidong, Burhenne, Jürgen, Bruckner, Thomas, Mueller, Sebastian, Haefeli, Walter E, Seitz, Helmut K

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Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion von Nassar, Yomna M., Hohmann, Nicolas, Michelet, Robin, Gottwalt, Katharina, Meid, Andreas D., Burhenne, Jürgen, Huisinga, Wilhelm, Haefeli, Walter E., Mikus, Gerd, Kloft, Charlotte

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Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives von Fresnais, Margaux, Yildirim, Esra, Karabulut, Seda, Jaeger, Dirk, Zoernig, Inka, Benzel, Julia, Pajtler, Kristian W., Pfister, Stefan M., Burhenne, Jurgen, Haefeli, Walter E., Longuespee, Remi

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