Orthotopic patient-derived xenografts of paediatric solid tumours von Stewart, Elizabeth, Federico, Sara M., Chen, Xiang, Shelat, Anang A., Bradley, Cori, Gordon, Brittney, Karlstrom, Asa, Twarog, Nathaniel R., Clay, Michael R., Bahrami, Armita, Freeman, Burgess B., Xu, Beisi, Zhou, Xin, Wu, Jianrong, Honnell, Victoria, Ocarz, Monica, Blankenship, Kaley, Dapper, Jason, Mardis, Elaine R., Wilson, Richard K., Downing, James, Zhang, Jinghui, Easton, John, Pappo, Alberto, Dyer, Michael A.

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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy von Badders, Nisha M, Korff, Ane, Miranda, Helen C, Vuppala, Pradeep K, Smith, Rebecca B, Winborn, Brett J, Quemin, Emmanuelle R, Sopher, Bryce L, Dearman, Jennifer, Messing, James, Kim, Nam Chul, Moore, Jennifer, Freibaum, Brian D, Kanagaraj, Anderson P, Fan, Baochang, Tillman, Heather, Chen, Ping-Chung, Wang, Yingzhe, Freeman III, Burgess B., Li, Yimei, Kim, Hong Joo, La Spada, Albert R, Taylor, J Paul

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Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma von Morfouace, Marie, Shelat, Anang, Jacus, Megan, Freeman, Burgess B., Turner, David, Robinson, Sarah, Zindy, Frederique, Wang, Yong-Dong, Finkelstein, David, Ayrault, Olivier, Bihannic, Laure, Puget, Stephanie, Li, Xiao-Nan, Olson, James M., Robinson, Giles W., Guy, R. Kiplin, Stewart, Clinton F., Gajjar, Amar, Roussel, Martine F.

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Targeting the DNA Repair Pathway in Ewing Sarcoma von Stewart, Elizabeth, Goshorn, Ross, Bradley, Cori, Griffiths, Lyra M., Benavente, Claudia, Twarog, Nathaniel R., Miller, Gregory M., Caufield, William, Freeman, Burgess B., Bahrami, Armita, Pappo, Alberto, Wu, Jianrong, Loh, Amos, Karlström, Åsa, Calabrese, Chris, Gordon, Brittney, Tsurkan, Lyudmila, Hatfield, M. Jason, Potter, Philip M., Snyder, Scott E., Thiagarajan, Suresh, Shirinifard, Abbas, Sablauer, Andras, Shelat, Anang A., Dyer, Michael A.

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The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma von Pan, Min, Wright, William C., Chapple, Richard H., Zubair, Asif, Sandhu, Manbir, Batchelder, Jake E., Huddle, Brandt C., Low, Jonathan, Blankenship, Kaley B., Wang, Yingzhe, Gordon, Brittney, Archer, Payton, Brady, Samuel W., Natarajan, Sivaraman, Posgai, Matthew J., Schuetz, John, Miller, Darcie, Kalathur, Ravi, Chen, Siquan, Connelly, Jon Patrick, Babu, M. Madan, Dyer, Michael A., Pruett-Miller, Shondra M., Freeman, Burgess B., Chen, Taosheng, Godley, Lucy A., Blanchard, Scott C., Stewart, Elizabeth, Easton, John, Geeleher, Paul

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Practical approaches to evaluating and optimizing brain exposure in early drug discovery von Freeman, Burgess B., Yang, Lei, Rankovic, Zoran

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Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice von Annu, Kavya, Yasuda, Kazuto, Caufield, William V, Freeman, 3rd, Burgess B, Schuetz, Erin G

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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma von He, Chen, Xu, Ke, Zhu, Xiaoyan, Dunphy, Paige S., Gudenas, Brian, Lin, Wenwei, Twarog, Nathaniel, Hover, Laura D., Kwon, Chang-Hyuk, Kasper, Lawryn H., Zhang, Junyuan, Li, Xiaoyu, Dalton, James, Jonchere, Barbara, Mercer, Kimberly S., Currier, Duane G., Caufield, William, Wang, Yingzhe, Xie, Jia, Broniscer, Alberto, Wetmore, Cynthia, Upadhyaya, Santhosh A., Qaddoumi, Ibrahim, Klimo, Paul, Boop, Frederick, Gajjar, Amar, Zhang, Jinghui, Orr, Brent A., Robinson, Giles W., Monje, Michelle, Freeman III, Burgess B., Roussel, Martine F., Northcott, Paul A., Chen, Taosheng, Rankovic, Zoran, Wu, Gang, Chiang, Jason, Tinkle, Christopher L., Shelat, Anang A., Baker, Suzanne J.

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses von Stewart, Elizabeth, McEvoy, Justina, Wang, Hong, Chen, Xiang, Honnell, Victoria, Ocarz, Monica, Gordon, Brittney, Dapper, Jason, Blankenship, Kaley, Yang, Yanling, Li, Yuxin, Shaw, Timothy I., Cho, Ji-Hoon, Wang, Xusheng, Xu, Beisi, Gupta, Pankaj, Fan, Yiping, Liu, Yu, Rusch, Michael, Griffiths, Lyra, Jeon, Jongrye, Freeman, Burgess B., Clay, Michael R., Pappo, Alberto, Easton, John, Shurtleff, Sheila, Shelat, Anang, Zhou, Xin, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Bahrami, Armita, Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Peng, Junmin, Downing, James R., Dyer, Michael A.

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Modeling and targeting of erythroleukemia by hematopoietic genome editing von Iacobucci, Ilaria, Qu, Chunxu, Varotto, Elena, Janke, Laura J., Yang, Xu, Seth, Aman, Shelat, Anang, Friske, Jake D., Fukano, Reiji, Yu, Jiyang, Freeman, Burgess B., Kennedy, James A., Sperling, Adam S., Zheng, Rena, Wang, Yingzhe, Jogiraju, Harini, Dickerson, Kirsten M., Payne-Turner, Debbie, Morris, Sarah M., Hollis, Emily S., Ghosn, Nina, Haggard, Georgia E., Lindsley, R. Coleman, Ebert, Benjamin L., Mullighan, Charles G.

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Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine von Howard, Thomas P, Oberlick, Elaine M, Rees, Matthew G, Arnoff, Taylor E, Pham, Minh-Tam, Brenan, Lisa, DoCarmo, Mariana, Hong, Andrew L, Kugener, Guillaume, Chou, Hsien-Chao, Drosos, Yiannis, Mathias, Kaeli M, Ramos, Pilar, Seashore-Ludlow, Brinton, Giacomelli, Andrew O, Wang, Xiaofeng, Freeman, 3rd, Burgess B, Blankenship, Kaley, Hoffmann, Lauren, Tiv, Hong L, Gokhale, Prafulla C, Johannessen, Cory M, Stewart, Elizabeth A, Schreiber, Stuart L, Hahn, William C, Roberts, Charles W M

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Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling von Blundon, Jay A., Roy, Noah C., Teubner, Brett J. W., Yu, Jing, Eom, Tae-Yeon, Sample, K. Jake, Pani, Amar, Smeyne, Richard J., Han, Seung Baek, Kerekes, Ryan A., Rose, Derek C., Hackett, Troy A., Vuppala, Pradeep K., Freeman, Burgess B., Zakharenko, Stanislav S.

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Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b... von Gaur, Aditya H, McCarthy, James S, Panetta, John C, Dallas, Ronald H, Woodford, John, Tang, Li, Smith, Amber M, Stewart, Tracy B, Branum, Kristen C, Freeman, Burgess B, Patel, Nehali D, John, Elizabeth, Chalon, Stephan, Ost, Shelley, Heine, Ryan N, Richardson, Julie L, Christensen, Robbin, Flynn, Patricia M, Van Gessel, Yvonne, Mitasev, Branko, Möhrle, Jörg J, Gusovsky, Fabian, Bebrevska, Lidiya, Guy, R Kiplin

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Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition von Shendy, Noha A. M., Bikowitz, Melissa, Sigua, Logan H., Zhang, Yang, Mercier, Audrey, Khashana, Yousef, Nance, Stephanie, Liu, Qi, Delahunty, Ian M., Robinson, Sarah, Goel, Vanshita, Rees, Matthew G., Ronan, Melissa A., Wang, Tingjian, Kocak, Mustafa, Roth, Jennifer A., Wang, Yingzhe, Freeman, Burgess B., Orr, Brent A., Abraham, Brian J., Roussel, Martine F., Schonbrunn, Ernst, Qi, Jun, Durbin, Adam D.

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Baloxavir Treatment Delays Influenza B Virus Transmission in Ferrets and Results in Limited Generation of Drug-Resistant Variants von Pascua, Philippe Noriel Q, Jones, Jeremy C, Marathe, Bindumadhav M, Seiler, Patrick, Caufield, William V, Freeman, 3rd, Burgess B, Webby, Richard J, Govorkova, Elena A

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Author Correction: Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy von Badders, Nisha M., Korff, Ane, Miranda, Helen C., Vuppala, Pradeep K., Smith, Rebecca B., Winborn, Brett J., Quemin, Emmanuelle R., Sopher, Bryce L., Dearman, Jennifer, Messing, James, Kim, Nam Chul, Moore, Jennifer, Freibaum, Brian D., Kanagaraj, Anderson P., Fan, Baochang, Tillman, Heather, Chen, Ping-Chung, Wang, Yingzhe, Freeman, Burgess B., Li, Yimei, Kim, Hong Joo, La Spada, Albert R., Taylor, J. Paul

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Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development von Gaur, Aditya H., Panetta, John C., Smith, Amber M., Dallas, Ronald H., Freeman, Burgess B., Stewart, Tracy B., Tang, Li, John, Elizabeth, Branum, Kristen C., Patel, Nehali D., Ost, Shelley, Heine, Ryan N., Richardson, Julie L., Hammill, Jared T., Bebrevska, Lidiya, Gusovsky, Fabian, Maki, Noritsugu, Yanagi, Toshiharu, Flynn, Patricia M., McCarthy, James S., Chalon, Stephan, Guy, R. Kiplin

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Evaluation of the Antitumor Efficacy, Pharmacokinetics, and Pharmacodynamics of the Histone Deacetylase Inhibitor Depsipeptide in Childhood Cancer Models In vivo von Graham, Claire, Tucker, Chandra, Creech, Jeremy, Favours, Edward, Billups, Catherine A, Liu, Tiebin, Fouladi, Maryam, Freeman, 3rd, Burgess B, Stewart, Clinton F, Houghton, Peter J

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Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine von Diouf, Barthelemy, Wing, Claudia, Panetta, John C., Eddins, Donnie, Lin, Wenwei, Yang, Wenjian, Fan, Yiping, Pei, Deqing, Cheng, Cheng, Delaney, Shannon M., Zhang, Wei, Bonten, Erik J., Crews, Kristine R., Paugh, Steven W., Li, Lie, Freeman, Burgess B., Autry, Robert J., Beard, Jordan A., Ferguson, Daniel C., Janke, Laura J., Ness, Kirsten K., Chen, Taosheng, Zakharenko, Stanislav S., Jeha, Sima, Pui, Ching‐Hon, Relling, Mary V., Eileen Dolan, M., Evans, William E.

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Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy von Zuckermann, Marc, He, Chen, Andrews, Jared, Bagchi, Aditi, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati J, Yang, Lei, Li, Yong, Zhu, Xiaoyan, Ocasio, Jennifer K, Budd, Kaitlin M, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhang, Junyuan, Xu, Ke, Hover, Laura, Roach, Jordan T, Chan, Kenneth Chun-Ho, Hofmann, Nina, McKinnon, Peter J, Pfister, Stefan M, Shelat, Anang A, Rankovic, Zoran, Freeman, 3rd, Burgess B, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J

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