Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial von Chapman, Kenneth R, Prof, Burdon, Jonathan G W, MD, Piitulainen, Eeva, MD, Sandhaus, Robert A, Prof, Seersholm, Niels, MD, Stocks, James M, MD, Stoel, Berend C, PhD, Huang, Liping, MD, Yao, Zhenling, MD, Edelman, Jonathan M, MD, McElvaney, Noel G, Prof

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A Phenomic Scan of the Norfolk Island Genetic Isolate Identifies a Major Pleiotropic Effect Locus Associated with Metabolic and Renal Disorder Markers von Benton, Miles C, Lea, Rodney A, Macartney-Coxson, Donia, Hanna, Michelle, Eccles, David A, Carless, Melanie A, Chambers, Geoffrey K, Bellis, Claire, Goring, Harald H, Curran, Joanne E, Harper, Jacquie L, Gibson, Gregory, Blangero, John, Griffiths, Lyn R

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Overview of rabies post-exposure prophylaxis access, procurement and distribution in selected countries in Asia and Africa, 2017–2018 von Sreenivasan, N, Li, A, Shiferaw, M, Tran, C.H, Wallace, R, Blanton, J, Knopf, L, Abela-Ridder, B, Hyde, T

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SimSpin v2.6.0—constructing synthetic spectral IFU cubes for comparison with observational surveys von Harborne, K. E., Serene, A., Davies, E. J. A., Derkenne, C., Vaughan, S., Burdon, A. I., Lagos, C. del P, McDermid, R., O’Toole, S., Power, C., Robotham, A. S. G., Santucci, G., Tobar, R.

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Fractional Flow Reserve–Guided PCI as Compared with Coronary Bypass Surgery von Fearon, William F, Zimmermann, Frederik M, De Bruyne, Bernard, Piroth, Zsolt, van Straten, Albert H.M, Szekely, Laszlo, Davidavičius, Giedrius, Kalinauskas, Gintaras, Mansour, Samer, Kharbanda, Rajesh, Östlund-Papadogeorgos, Nikolaos, Aminian, Adel, Oldroyd, Keith G, Al-Attar, Nawwar, Jagic, Nikola, Dambrink, Jan-Henk E, Kala, Petr, Angerås, Oskar, MacCarthy, Philip, Wendler, Olaf, Casselman, Filip, Witt, Nils, Mavromatis, Kreton, Miner, Steven E.S, Sarma, Jaydeep, Engstrøm, Thomas, Christiansen, Evald H, Tonino, Pim A.L, Reardon, Michael J, Lu, Di, Ding, Victoria Y, Kobayashi, Yuhei, Hlatky, Mark A, Mahaffey, Kenneth W, Desai, Manisha, Woo, Y. Joseph, Yeung, Alan C, Pijls, Nico H.J

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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error von Tedja, Milly S., Wojciechowski, Robert, Hysi, Pirro G., Eriksson, Nicholas, Furlotte, Nicholas A., Verhoeven, Virginie J. M., Iglesias, Adriana I., Meester-Smoor, Magda A., Tompson, Stuart W., Fan, Qiao, Khawaja, Anthony P., Cheng, Ching-Yu, Höhn, René, Yamashiro, Kenji, Wenocur, Adam, Grazal, Clare, Haller, Toomas, Metspalu, Andres, Wedenoja, Juho, Jonas, Jost B., Wang, Ya Xing, Xie, Jing, Mitchell, Paul, Foster, Paul J., Klein, Barbara E. K., Klein, Ronald, Paterson, Andrew D., Hosseini, S. Mohsen, Shah, Rupal L., Williams, Cathy, Teo, Yik Ying, Tham, Yih Chung, Gupta, Preeti, Zhao, Wanting, Shi, Yuan, Saw, Woei-Yuh, Tai, E-Shyong, Sim, Xue Ling, Huffman, Jennifer E., Polašek, Ozren, Hayward, Caroline, Bencic, Goran, Rudan, Igor, Wilson, James F., Joshi, Peter K., Tsujikawa, Akitaka, Matsuda, Fumihiko, Whisenhunt, Kristina N., Zeller, Tanja, van der Spek, Peter J., Haak, Roxanna, Meijers-Heijboer, Hanne, van Leeuwen, Elisabeth M., Iyengar, Sudha K., Lass, Jonathan H., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., Vingerling, Johannes R., Lehtimäki, Terho, Raitakari, Olli T., Biino, Ginevra, Concas, Maria Pina, Schwantes-An, Tae-Hwi, Igo, Robert P., Cuellar-Partida, Gabriel, Martin, Nicholas G., Craig, Jamie E., Gharahkhani, Puya, Williams, Katie M., Nag, Abhishek, Rahi, Jugnoo S., Cumberland, Phillippa M., Delcourt, Cécile, Bellenguez, Céline, Ried, Janina S., Bergen, Arthur A., Meitinger, Thomas, Gieger, Christian, Wong, Tien Yin, Hewitt, Alex W., Mackey, David A., Simpson, Claire L., Pfeiffer, Norbert, Pärssinen, Olavi, Baird, Paul N., Vitart, Veronique, Amin, Najaf, van Duijn, Cornelia M., Bailey-Wilson, Joan E., Young, Terri L., Saw, Seang-Mei, Stambolian, Dwight, MacGregor, Stuart, Guggenheim, Jeremy A., Tung, Joyce Y., Hammond, Christopher J., Klaver, Caroline C. W.

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Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass von Shroyer, A. Laurie, Hattler, Brack, Wagner, Todd H, Collins, Joseph F, Baltz, Janet H, Quin, Jacquelyn A, Almassi, G. Hossein, Kozora, Elizabeth, Bakaeen, Faisal, Cleveland, Joseph C, Bishawi, Muath, Grover, Frederick L

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Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia von Verhoeven, Virginie J M, Hysi, Pirro G, Wojciechowski, Robert, Guggenheim, Jeremy A, Höhn, René, MacGregor, Stuart, Hewitt, Alex W, Nag, Abhishek, Cheng, Ching-Yu, Yonova-Doing, Ekaterina, Zhou, Xin, Ikram, M Kamran, McMahon, George, Kemp, John P, Pourcain, Beate St, Simpson, Claire L, Mäkelä, Kari-Matti, Lehtimäki, Terho, Kähönen, Mika, Paterson, Andrew D, Hosseini, S Mohsen, Wong, Hoi Suen, Xu, Liang, Wedenoja, Juho, Yip, Shea Ping, Ho, Daniel W H, Pang, Chi Pui, Chen, Li Jia, Burdon, Kathryn P, Craig, Jamie E, Klein, Barbara E K, Klein, Ronald, Haller, Toomas, Metspalu, Andres, Khor, Chiea-Chuen, Tai, E-Shyong, Aung, Tin, Vithana, Eranga, Tay, Wan-Ting, Barathi, Veluchamy A, Chen, Peng, Li, Ruoying, Liao, Jiemin, Zheng, Yingfeng, Ong, Rick T, Döring, Angela, Evans, David M, Timpson, Nicholas J, Verkerk, Annemieke J M H, Meitinger, Thomas, Raitakari, Olli, Hawthorne, Felicia, Spector, Tim D, Pirastu, Mario, Murgia, Federico, Ang, Wei, Mishra, Aniket, Montgomery, Grant W, Pennell, Craig E, Cumberland, Phillippa M, Cotlarciuc, Ioana, Mitchell, Paul, Wang, Jie Jin, Schache, Maria, Janmahasatian, Sarayut, Jr, Robert P Igo, Lass, Jonathan H, Chew, Emily, Iyengar, Sudha K, Gorgels, Theo G M F, Rudan, Igor, Hayward, Caroline, Wright, Alan F, Polasek, Ozren, Vatavuk, Zoran, Wilson, James F, Fleck, Brian, Zeller, Tanja, Mirshahi, Alireza, Müller, Christian, Uitterlinden, André G, Rivadeneira, Fernando, Vingerling, Johannes R, Hofman, Albert, Oostra, Ben A, Amin, Najaf, Bergen, Arthur A B, Teo, Yik-Ying, Rahi, Jugnoo S, Vitart, Veronique, Williams, Cathy, Baird, Paul N, Oexle, Konrad, Pfeiffer, Norbert, Mackey, David A, Young, Terri L, Saw, Seang-Mei, Stambolian, Dwight, Klaver, Caroline C, Hammond, Christopher J

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Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass von Zenati, Marco A, Bhatt, Deepak L, Bakaeen, Faisal G, Stock, Eileen M, Biswas, Kousick, Gaziano, J. Michael, Kelly, Rosemary F, Tseng, Elaine E, Bitondo, Jerene, Quin, Jacquelyn A, Almassi, G. Hossein, Haime, Miguel, Hattler, Brack, DeMatt, Ellen, Scrymgeour, Alexandra, Huang, Grant D

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Childbearing May Increase the Risk of Nondiabetic Cataract in Chinese Women's Old Age von Chu, Cheng-I, Fang, Ya, Han, Yaofeng, Yuan, Manqiong

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Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom von Patel, Brijesh V., Haar, Shlomi, Handslip, Rhodri, Auepanwiriyakul, Chaiyawan, Lee, Teresa Mei-Ling, Patel, Sunil, Harston, J. Alex, Hosking-Jervis, Feargus, Kelly, Donna, Sanderson, Barnaby, Borgatta, Barbara, Tatham, Kate, Welters, Ingeborg, Camporota, Luigi, Gordon, Anthony C., Komorowski, Matthieu, Antcliffe, David, Prowle, John R., Puthucheary, Zudin, Faisal, Aldo A.

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On-Pump versus Off-Pump Coronary-Artery Bypass Surgery von Shroyer, A. Laurie, Grover, Frederick L, Hattler, Brack, Collins, Joseph F, McDonald, Gerald O, Kozora, Elizabeth, Lucke, John C, Baltz, Janet H, Novitzky, Dimitri

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways von Duffy, David L., Zhu, Gu, Li, Xin, Sanna, Marianna, Iles, Mark M., Jacobs, Leonie C., Evans, David M., Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H., Kraft, Peter, Visconti, Alessia, Taylor, John C., Liu, Fan, Wright, Margaret J., Henders, Anjali K., Bowdler, Lisa, Glass, Dan, Ikram, M. Arfan, Uitterlinden, André G., Madden, Pamela A., Heath, Andrew C., Nelson, Elliot C., Green, Adele C., Chanock, Stephen, Barrett, Jennifer H., Brown, Matthew A., Hayward, Nicholas K., MacGregor, Stuart, Sturm, Richard A., Hewitt, Alex W., Kayser, Manfred, Hunter, David J., Newton Bishop, Julia A., Spector, Timothy D., Montgomery, Grant W., Mackey, David A., Smith, George Davey, Nijsten, Tamar E., Bishop, D. Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali, Martin, Nicholas G.

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Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration: A Mendelian Randomization Study von Kuan, Valerie, Warwick, Alasdair, Hingorani, Aroon, Tufail, Adnan, Cipriani, Valentina, Burgess, Stephen, Sofat, Reecha

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Bone Marrow Stem Cell Derived Paracrine Factors for Regenerative Medicine: Current Perspectives and Therapeutic Potential von Prakash, Satya, Paul, Arghya, Noiseux, Nicolas, Shum-Tim, Dominique, Burdon, Tom J.

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Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes von Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A, Shi, Jianxin, Xu, Mai, Goldstein, Alisa M, Trower, Adam J, Bishop, D Timothy, Iles, Mark M, Duffy, David L, MacGregor, Stuart, Amundadottir, Laufey T, Law, Matthew H, Loftus, Stacie K, Pavan, William J, Brown, Kevin M

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Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia von Tideman, J. Willem L, Pärssinen, Olavi, Haarman, Annechien E. G, Khawaja, Anthony P, Wedenoja, Juho, Williams, Katie M, Biino, Ginevra, Ding, Xiaohu, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T, Cheng, Ching-Yu, Jonas, Jost B, Young, Terri L, Bailey-Wilson, Joan E, Rahi, Jugnoo, Williams, Cathy, He, Mingguang, Mackey, David A, Guggenheim, Jeremy A

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Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma von Hamel, Andrew R., Yan, Wenjun, Rouhana, John M., Monovarfeshani, Aboozar, Jiang, Xinyi, Mehta, Puja A., Advani, Jayshree, Luo, Yuyang, Liang, Qingnan, Rajasundaram, Skanda, Shrivastava, Arushi, Duchinski, Katherine, Mantena, Sreekar, Wang, Jiali, van Zyl, Tavé, Pasquale, Louis R., Swaroop, Anand, Gharahkhani, Puya, Khawaja, Anthony P., MacGregor, Stuart, Chen, Rui, Vitart, Veronique, Sanes, Joshua R., Wiggs, Janey L., Segrè, Ayellet V.

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Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error von Ikram, M. Kamran, Barathi, Veluchamy A., Kemp, John P., Wang, Ya Xing, Wright, Alan F., Amin, Najaf, Tay, Wan-Ting, Hayward, Caroline, Polasek, Ozren, Vatavuk, Zoran, Pang, Chi Pui, Wegner, Aharon, Yip, Shea Ping, Murgia, Federico, Portas, Laura, Ang, Wei, Fan, Qiao, Zhou, Xin, Iyengar, Sudha K., Vital, Mark, Yoo, Sonia, Maguire, Leo, McCulley, James, Renucci, Ann, Oliva, Matt, Brown, Marlene, Reeves, Sherman, Hamilton, Stephen, Kelly, Kathleen, Shaughnessy, Michael, Steinemann, Thomas, Mifflin, Mark, Chodosh, James, Galentine, Paul G., Mannis, Mark, Varma, Rohit, Wedenoja, Juho, Mirshahi, Alireza, Brown, Matthew A., Corvin, Aiden, Duncanson, Audrey, Markus, Hugh S., Rautanen, Anna, Viswanathan, Ananth C., Giannoulatou, Eleni, Donnelly, Peter, Hammond, Naomi, McCann, Owen T., Ricketts, Michelle, Widaa, Sara, Yonova-Doing, Ekaterina, Klein, Ronald, Miller, D., Whitehouse, F., McLellan, M., Golden, E., Arrigg, P., Gauthier-Kelly, C., Lopes-Virella, M., Colwell, J., Farr, A., Elsing, S., Kaminski, L., Lorenzi, G., Johnsonbaugh, S., Liss, R., Gordon, J., Martin, C.L., Pop-Busui, R., Smith, A., Gothrup, J., Prosser, L., Schwartz, S., Maschak-Carey, B.J., Morrison, A., Meyer, D., Strowig, S., Gordon, A., Hokanson, J., Ginsberg, J., Van Ottingham, L., Harth, J., May, M., Adkins, T., White, N., Fradkin, J., Siebert, C., Danis, R., Dingledine, J., Chavers, B., Burzuk, B., Low, P., Wong, N., Fox, M., Clark, C., Zhang, L., Pang, Chi Pui, Inoko, Hidetoshi, Mitchell, Paul, Stambolian, Dwight

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Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries von Gorman, Bryan R., Voloudakis, Georgios, Igo, Robert P., Kinzy, Tyler, Halladay, Christopher W., Bigdeli, Tim B., Zeng, Biao, Venkatesh, Sanan, Cooke Bailey, Jessica N., Crawford, Dana C., Markianos, Kyriacos, Dong, Frederick, Schreiner, Patrick A., Zhang, Wen, Hadi, Tamer, Anger, Matthew D., Stockwell, Amy, Melles, Ronald B., Yin, Jie, Choquet, Hélène, Kaye, Rebecca, Patasova, Karina, Patel, Praveen J., Yaspan, Brian L., Jorgenson, Eric, Hysi, Pirro G., Lotery, Andrew J., Gaziano, J. Michael, Tsao, Philip S., Fliesler, Steven J., Sullivan, Jack M., Greenberg, Paul B., Wu, Wen-Chih, Assimes, Themistocles L., Pyarajan, Saiju, Roussos, Panos, Peachey, Neal S., Iyengar, Sudha K.

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