3D chromatin remodelling in the germ line modulates genome evolutionary plasticity von Álvarez-González, Lucía, Burden, Frances, Doddamani, Dadakhalandar, Malinverni, Roberto, Leach, Emma, Marín-García, Cristina, Marín-Gual, Laia, Gubern, Albert, Vara, Covadonga, Paytuví-Gallart, Andreu, Buschbeck, Marcus, Ellis, Peter J. I., Farré, Marta, Ruiz-Herrera, Aurora

Volltext

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease von Watt, Stephen, Vasquez, Louella, Walter, Klaudia, Mann, Alice L., Kundu, Kousik, Chen, Lu, Sims, Ying, Ecker, Simone, Burden, Frances, Farrow, Samantha, Farr, Ben, Iotchkova, Valentina, Elding, Heather, Mead, Daniel, Tardaguila, Manuel, Ponstingl, Hannes, Richardson, David, Datta, Avik, Flicek, Paul, Clarke, Laura, Downes, Kate, Pastinen, Tomi, Fraser, Peter, Frontini, Mattia, Javierre, Biola-Maria, Spivakov, Mikhail, Soranzo, Nicole

Volltext

Chromosome contacts in activated T cells identify autoimmune disease candidate genes von Burren, Oliver S, Rubio García, Arcadio, Javierre, Biola-Maria, Rainbow, Daniel B, Cairns, Jonathan, Cooper, Nicholas J, Lambourne, John J, Schofield, Ellen, Castro Dopico, Xaquin, Ferreira, Ricardo C, Coulson, Richard, Burden, Frances, Rowlston, Sophia P, Downes, Kate, Wingett, Steven W, Frontini, Mattia, Ouwehand, Willem H, Fraser, Peter, Spivakov, Mikhail, Todd, John A, Wicker, Linda S, Cutler, Antony J, Wallace, Chris

Volltext

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome von Sims, Matthew C., Mayer, Louisa, Collins, Janine H., Bariana, Tadbir K., Megy, Karyn, Lavenu-Bombled, Cecile, Seyres, Denis, Kollipara, Laxmikanth, Burden, Frances S., Greene, Daniel, Lee, Dave, Rodriguez-Romera, Antonio, Alessi, Marie-Christine, Astle, William J., Bahou, Wadie F., Bury, Loredana, Chalmers, Elizabeth, Da Silva, Rachael, De Candia, Erica, Deevi, Sri V.V., Farrow, Samantha, Gomez, Keith, Grassi, Luigi, Greinacher, Andreas, Gresele, Paolo, Hart, Dan, Hurtaud, Marie-Françoise, Kelly, Anne M., Kerr, Ron, Le Quellec, Sandra, Leblanc, Thierry, Leinøe, Eva B., Mapeta, Rutendo, McKinney, Harriet, Michelson, Alan D., Morais, Sara, Nugent, Diane, Papadia, Sofia, Park, Soo J., Pasi, John, Podda, Gian Marco, Poon, Man-Chiu, Reed, Rachel, Sekhar, Mallika, Shalev, Hanna, Sivapalaratnam, Suthesh, Steinberg-Shemer, Orna, Stephens, Jonathan C., Tait, Robert C., Turro, Ernest, Wu, John K.M., Zieger, Barbara, Kuijpers, Taco W., Whetton, Anthony D., Sickmann, Albert, Freson, Kathleen, Downes, Kate, Erber, Wendy N., Frontini, Mattia, Nurden, Paquita, Ouwehand, Willem H., Favier, Remi, Guerrero, Jose A.

Volltext

Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia von Bariana, Tadbir K, Labarque, Veerle, Heremans, Jessica, Thys, Chantal, De Reys, Mara, Greene, Daniel, Jenkins, Benjamin, Grassi, Luigi, Seyres, Denis, Burden, Frances, Whitehorn, Deborah, Shamardina, Olga, Papadia, Sofia, Gomez, Keith, BioResource, Nihr, Van Geet, Chris, Koulman, Albert, Ouwehand, Willem H, Ghevaert, Cedric, Frontini, Mattia, Turro, Ernest, Freson, Kathleen

Volltext

Exploring gender differences in dating violence/harassment prevention programming in middle schools: results from a randomized experiment von Taylor, Bruce G., Stein, Nan, Burden, Frances F.

Volltext

Knockdown of USP18 Increases Alpha 2a Interferon Signaling and Induction of Interferon-Stimulating Genes but Does Not Increase Antiviral Activity in Huh7 Cells von MURRAY, E. J, BURDEN, Frances, HORSCROFT, Nigel, SMITH-BURCHNELL, Caroline, WESTBY, Mike

Volltext

In Vitro Characterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy von Lavender, Helen, Brady, Kevin, Burden, Frances, Delpuech-Adams, Oona, Denise, Hubert, Palmer, Amy, Perkins, Hannah, Savic, Boris, Scott, Sarah, Smith-Burchnell, Caroline, Troke, Phil, Wright, J. Fraser, Suhy, David, Corbau, Romu

Volltext

Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision von Denise, Hubert, Moschos, Sterghios A., Sidders, Benjamin, Burden, Frances, Perkins, Hannah, Carter, Nikki, Stroud, Tim, Kennedy, Michael, Fancy, Sally-Ann, Lapthorn, Cris, Lavender, Helen, Kinloch, Ross, Suhy, David, Corbau, Romu

Volltext

A shared ‘vulnerability code’ underpins varying sources of DNA damage throughout paternal germline transmission in mouse von Burden, Frances, Ellis, Peter J I, Farré, Marta

Volltext

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters von Javierre, Biola M., Burren, Oliver S., Wilder, Steven P., Kreuzhuber, Roman, Hill, Steven M., Sewitz, Sven, Cairns, Jonathan, Wingett, Steven W., Várnai, Csilla, Thiecke, Michiel J., Burden, Frances, Farrow, Samantha, Cutler, Antony J., Rehnström, Karola, Downes, Kate, Grassi, Luigi, Kostadima, Myrto, Freire-Pritchett, Paula, Wang, Fan, Martens, Joost H., Kim, Bowon, Sharifi, Nilofar, Janssen-Megens, Eva M., Yaspo, Marie-Laure, Linser, Matthias, Kovacsovics, Alexander, Clarke, Laura, Richardson, David, Datta, Avik, Flicek, Paul, Stunnenberg, Hendrik G., Todd, John A., Zerbino, Daniel R., Stegle, Oliver, Ouwehand, Willem H., Frontini, Mattia, Wallace, Chris, Spivakov, Mikhail, Fraser, Peter

Volltext

Explaining Variability in High School Students' Access to and Enrollment in Career Academies and Career Theme Clusters in Florida: Multi-Level Analyses of Student and School Factor... von Evan, Aimee, Burden, Frances, Gheen, Margaret, Smerdon, Becky

Volltext

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types von Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O, Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L, Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G, Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W, Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S

Volltext

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types von Paul, Dirk S., Teschendorff, Andrew E., Dang, Mary A.N., Lowe, Robert, Hawa, Mohammed I., Ecker, Simone, Beyan, Huriya, Cunningham, Stephanie, Fouts, Alexandra R., Ramelius, Anita, Burden, Frances, Farrow, Samantha, Rowlston, Sophia, Rehnstrom, Karola, Frontini, Mattia, Downes, Kate, Busche, Stephan, Cheung, Warren A., Ge, Bing, Simon, Marie-Michelle, Bujold, David, Kwan, Tony, Bourque, Guillaume, Datta, Avik, Lowy, Ernesto, Clarke, Laura, Flicek, Paul, Libertini, Emanuele, Heath, Simon, Gut, Marta, Gut, Ivo G, Ouwehand, Willem H., Pastinen, Tomi, Soranzo, Nicole, Hofer, Sabine E., Karges, Beate, Meissner, Thomas, Boehm, Bernhard O., Cilio, Corrado, Elding Larsson, Helena, Lernmark, Åke, Steck, Andrea K., Rakyan, Vardhman K., Beck, Stephan, Leslie, R. David

Volltext

Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment von Choudry, Fizzah A., Bagger, Frederik O., Macaulay, Iain C., Farrow, Samantha, Burden, Frances, Kempster, Carly, McKinney, Harriet, Olsen, Lars R., Huang, Ni, Downes, Kate, Voet, Thierry, Uppal, Rakesh, Martin, John F., Mathur, Anthony, Ouwehand, Willem H., Laurenti, Elisa, Teichmann, Sarah A., Frontini, Mattia

Volltext

Project ALERT with outside leaders: what leader characteristics are important for success? von St Pierre, Tena L, Osgood, D Wayne, Siennick, Sonja E, Kauh, Tina J, Burden, Frances F

Volltext

Germline mutations in the transcription factor IKZF5 cause thrombocytopenia von Lentaigne, Claire, Greene, Daniel, Sivapalaratnam, Suthesh, Favier, Remi, Seyres, Denis, Thys, Chantal, Grassi, Luigi, Mangles, Sarah, Sibson, Keith, Stubbs, Matthew, Burden, Frances, Bordet, Jean-Claude, Armari-Alla, Corinne, Erber, Wendy, Farrow, Samantha, Gleadall, Nicholas, Gomez, Keith, Megy, Karyn, Papadia, Sofia, Penkett, Christopher J., Sims, Matthew C., Stefanucci, Luca, Stephens, Jonathan C., Read, Randy J., Stirrups, Kathleen E., Ouwehand, Willem H., Laffan, Michael A., Frontini, Mattia, Freson, Kathleen, Turro, Ernest

Volltext

Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas von Grassi, Luigi, Izuogu, Osagie G., Jorge, Natasha A. N., Seyres, Denis, Bustamante, Mariona, Burden, Frances, Farrow, Samantha, Farahi, Neda, Martin, Fergal J., Frankish, Adam, Mudge, Jonathan M., Kostadima, Myrto, Petersen, Romina, Lambourne, John J., Rowlston, Sophia, Martin-Rendon, Enca, Clarke, Laura, Downes, Kate, Estivill, Xavier, Flicek, Paul, Martens, Joost H. A., Yaspo, Marie-Laure, Stunnenberg, Hendrik G., Ouwehand, Willem H., Passetti, Fabio, Turro, Ernest, Frontini, Mattia

Volltext

Platelet function is modified by common sequence variation in megakaryocyte super enhancers von Petersen, Romina, Lambourne, John J., Javierre, Biola M., Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M., Tomé, Ana R., Elding, Heather, van Geffen, Johanna P., Jiang, Tao, Farrow, Samantha, Cairns, Jonathan, Al-Subaie, Abeer M., Ashford, Sofie, Attwood, Antony, Batista, Joana, Bouman, Heleen, Burden, Frances, Choudry, Fizzah A., Clarke, Laura, Flicek, Paul, Garner, Stephen F., Haimel, Matthias, Kempster, Carly, Ladopoulos, Vasileios, Lenaerts, An-Sofie, Materek, Paulina M., McKinney, Harriet, Meacham, Stuart, Mead, Daniel, Nagy, Magdolna, Penkett, Christopher J., Rendon, Augusto, Seyres, Denis, Sun, Benjamin, Tuna, Salih, van der Weide, Marie-Elise, Wingett, Steven W., Martens, Joost H., Stegle, Oliver, Richardson, Sylvia, Vallier, Ludovic, Roberts, David J., Freson, Kathleen, Wernisch, Lorenz, Stunnenberg, Hendrik G., Danesh, John, Fraser, Peter, Soranzo, Nicole, Butterworth, Adam S., Heemskerk, Johan W., Turro, Ernest, Spivakov, Mikhail, Ouwehand, Willem H., Astle, William J., Downes, Kate, Kostadima, Myrto, Frontini, Mattia

Volltext

Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment von Choudry, Fizzah A, Bagger, Frederik O, Macaulay, Iain C, Farrow, Samantha, Burden, Frances, Kempster, Carly, McKinney, Harriet, Olsen, Lars R, Huang, Ni, Downes, Kate, Voet, Thierry, Uppal, Rakesh, Martin, John F, Mathur, Anthony, Ouwehand, Willem H, Laurenti, Elisa, Teichmann, Sarah A, Frontini, Mattia

Volltext