N-Acetyl-p-benzoquinone Imine, the Toxic Metabolite of Acetaminophen, Is a Topoisomerase II Poison von Bender, Ryan P, Lindsey, R. Hunter, Burden, D. Andrew, Osheroff, Neil

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Binding of Etoposide to Topoisomerase II in the Absence of DNA:  Decreased Affinity as a Mechanism of Drug Resistance von Kingma, Paul S, Burden, D. Andrew, Osheroff, Neil

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Topoisomerase II·Etoposide Interactions Direct the Formation of Drug-induced Enzyme-DNA Cleavage Complexes von Burden, D. Andrew, Kingma, Paul S., Froelich-Ammon, Stacie J., Bjornsti, Mary-Ann, Patchan, Marcia W., Thompson, Richard B., Osheroff, Neil

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DNA Topoisomerases as Targets for the Anticancer Drug TAS-103:  Primary Cellular Target and DNA Cleavage Enhancement von Wilson Byl, Jo Ann, Fortune, John M, Burden, D. Andrew, Nitiss, John L, Utsugi, Teruhiro, Yamada, Yuji, Osheroff, Neil

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In vitro evolution of preferred topoisomerase II DNA cleavage sites von Burden, D.A, Osheroff, N

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Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme von Burden, D.Andrew, Osheroff, Neil

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Increased Drug Affinity as the Mechanistic Basis for Drug Hypersensitivity of a Mutant Type II Topoisomerase von Stacie, J. Froelich-Ammon, Burden, D. Andrew, Patchan, Marcia W., Elsea, Sarah H., Thompson, Richard B., Osheroff, Neil

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Phosphorylation of the .alpha.- and .beta.-Isoforms of DNA Topoisomerase II Is Qualitatively Different in Interphase and Mitosis in Chinese Hamster Ovary Cells von Burden, D. Andrew, Sullivan, Daniel M

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Quinolones Share a Common Interaction Domain on Topoisomerase II with Other DNA Cleavage-Enhancing Antineoplastic Drugs von Elsea, Sarah H, Westergaard, Majken, Burden, D. Andrew, Lomenick, Jefferson P, Osheroff, Neil

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Topoisomerase II·Etoposide Interactions Direct the Formation of Drug-induced Enzyme-DNA Cleavage Complexes von D. Andrew Burden, Paul S. Kingma, Stacie J. Froelich-Ammon, Mary-Ann Bjornsti, Marcia W. Patchan, Richard B. Thompson, Neil Osheroff

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Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study von Price, David B, Prof, Rigazio, Anna, MSc, Campbell, Jonathan D, PhD, Bleecker, Eugene R, MD, Corrigan, Christopher J, PhD, Thomas, Mike, PhD, Wenzel, Sally E, MD, Wilson, Andrew M, MD, Small, Mary Buatti, MS, Gopalan, Gokul, MD, Ashton, Valerie L, PhD, Burden, Anne, MSc, Hillyer, Elizabeth V, DVM, Kerkhof, Marjan, PhD, Pavord, Ian D, FMedSci

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Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010 von Feigin, Valery L, Prof, Forouzanfar, Mohammad H, Prof, Krishnamurthi, Rita, PhD, Mensah, George A, MD, Connor, Myles, MBBCh, Bennett, Derrick A, PhD, Moran, Andrew E, Prof, Sacco, Ralph L, Prof, Anderson, Laurie, Prof, Truelsen, Thomas, MD, O'Donnell, Martin, Prof, Venketasubramanian, Narayanaswamy, MBBS, Barker-Collo, Suzanne, Prof, Lawes, Carlene M M, MBChB, Wang, Wenzhi, Prof, Shinohara, Yukito, MD, Witt, Emma, MSc, Ezzati, Majid, Prof, Naghavi, Mohsen, Prof, Murray, Christopher, Prof

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The association of fatigue, pain, depression and anxiety with work and activity impairment in immune mediated inflammatory diseases von Enns, Murray W, Bernstein, Charles N, Kroeker, Kristine, Graff, Lesley, Walker, John R, Lix, Lisa M, Hitchon, Carol A, El-Gabalawy, Renée, Fisk, John D, Marrie, Ruth Ann

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Cancer incidence and mortality in 23 000 patients with type 1 diabetes in the UK: Long‐term follow‐up von Swerdlow, Anthony J., Jones, Michael E., Slater, Stefan D., Burden, Andrew C. F., Botha, Johannes L., Waugh, Norman R., Morris, Andrew D., Gatling, Wendy, Gillespie, Kathleen M., Patterson, Christopher C., Schoemaker, Minouk J.

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Global Cardiovascular and Renal Outcomes of Reduced GFR von Thomas, Bernadette, Matsushita, Kunihiro, Abate, Kalkidan Hassen, Al-Aly, Ziyad, Ärnlöv, Johan, Asayama, Kei, Atkins, Robert, Badawi, Alaa, Ballew, Shoshana H, Banerjee, Amitava, Barregård, Lars, Barrett-Connor, Elizabeth, Basu, Sanjay, Bello, Aminu K, Bensenor, Isabela, Bergstrom, Jaclyn, Bikbov, Boris, Blosser, Christopher, Brenner, Hermann, Carrero, Juan-Jesus, Chadban, Steve, Cirillo, Massimo, Cortinovis, Monica, Courville, Karen, Dandona, Lalit, Dandona, Rakhi, Estep, Kara, Fernandes, João, Fischer, Florian, Fox, Caroline, Gansevoort, Ron T, Gona, Philimon N, Gutierrez, Orlando M, Hamidi, Samer, Hanson, Sarah Wulf, Himmelfarb, Jonathan, Jassal, Simerjot K, Jee, Sun Ha, Jha, Vivekanand, Jimenez-Corona, Aida, Jonas, Jost B, Kengne, Andre Pascal, Khader, Yousef, Khang, Young-Ho, Kim, Yun Jin, Klein, Barbara, Klein, Ronald, Kokubo, Yoshihiro, Kolte, Dhaval, Lee, Kristine, Levey, Andrew S, Li, Yongmei, Lotufo, Paulo, El Razek, Hassan Magdy Abd, Mendoza, Walter, Metoki, Hirohito, Mok, Yejin, Muraki, Isao, Muntner, Paul M, Noda, Hiroyuki, Ohkubo, Takayoshi, Ortiz, Alberto, Perico, Norberto, Polkinghorne, Kevan, Al-Radaddi, Rajaa, Remuzzi, Giuseppe, Roth, Gregory, Rothenbacher, Dietrich, Satoh, Michihiro, Saum, Kai-Uwe, Sawhney, Monika, Schöttker, Ben, Shankar, Anoop, Shlipak, Michael, Silva, Diego Augusto Santos, Toyoshima, Hideaki, Ukwaja, Kingsley, Umesawa, Mitsumasa, Vollset, Stein Emil, Warnock, David G, Werdecker, Andrea, Yamagishi, Kazumasa, Yano, Yuichiro, Yonemoto, Naohiro, Zaki, Maysaa El Sayed, Naghavi, Mohsen, Forouzanfar, Mohammad H, Murray, Christopher J L, Coresh, Josef, Vos, Theo

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Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010 von Krishnamurthi, Rita V, PhD, Feigin, Valery L, Prof, Forouzanfar, Mohammad H, Prof, Mensah, George A, MD, Connor, Myles, MBBCh, Bennett, Derrick A, PhD, Moran, Andrew E, Prof, Sacco, Ralph L, Prof, Anderson, Laurie M, PhD, Truelsen, Thomas, MD, O'Donnell, Martin, Prof, Venketasubramanian, Narayanaswamy, MBBS, Barker-Collo, Suzanne, Prof, Lawes, Carlene M M, MBChB, Wang, Wenzhi, PhD, Shinohara, Yukito, MD, Witt, Emma, MSc, Ezzati, Majid, Prof, Naghavi, Mohsen, Prof, Murray, Christopher, Prof

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Global Sodium Consumption and Death from Cardiovascular Causes von Mozaffarian, Dariush, Fahimi, Saman, Singh, Gitanjali M, Micha, Renata, Khatibzadeh, Shahab, Engell, Rebecca E, Lim, Stephen, Danaei, Goodarz, Ezzati, Majid, Powles, John

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Global Mortality From Firearms, 1990-2016 von Naghavi, Mohsen, Marczak, Laurie B, Kutz, Michael, Shackelford, Katya Anne, Miller-Petrie, Molly, Aichour, Miloud Taki Eddine, Alghnam, Suliman A, Antonio, Carl Abelardo T, Aremu, Olatunde, Asadi-Lari, Mohsen, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Bazargan-Hejazi, Shahrzad, Bennett, James R, Bhutta, Zulfiqar A, Bilal, Arebu Issa, Borschmann, Rohan, Brazinova, Alexandra, Castañeda-Orjuela, Carlos A, Dandona, Rakhi, Dargan, Paul I, Ding, Eric L, Phuc Do, Huyen, Doyle, Kerrie E, Driscoll, Tim Robert, El-Khatib, Ziad, Endries, Aman Yesuf, Esteghamati, Alireza, Farzadfar, Farshad, Feigin, Valery L, Fischer, Florian, Gebrehiwot, Tsegaye Tewelde, Gutiérrez, Reyna Alma, Hafezi-Nejad, Nima, Haghparast Bidgoli, Hassan, Haro, Josep Maria, Hassen, Hamid Yimam, Hawley, Caitlin, Hu, Guoqing, Ilesanmi, Olayinka Stephen, Jakovljevic, Mihajlo, James, Spencer L, Jayaraman, Sudha, Jonas, Jost B, Kasaeian, Amir, Keiyoro, Peter Njenga, Khader, Yousef, Khalil, Ibrahim A, Khubchandani, Jagdish, Ahmad Kiadaliri, Aliasghar, Kieling, Christian, Kim, Yun Jin, Kumar, G. Anil, Lami, Faris Hasan, Lansingh, Van C, Larson, Heidi Jane, Linn, Shai, Magdy Abd El Razek, Muhammed, Malekzadeh, Reza, Carvalho Malta, Deborah, Mason-Jones, Amanda J, Matzopoulos, Richard, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Miller, Ted R, Mohammed, Shafiu, Moradi-Lakeh, Maziar, Mori, Rintaro, Nand, Devina, Tat Nguyen, Cuong, Olagunju, Andrew T, Polinder, Suzanne, Pourmalek, Farshad, Qorbani, Mostafa, Rahimi-Movaghar, Afarin, Rahman, Mahfuzar, Rai, Rajesh Kumar, Rawaf, David Laith, Rawaf, Salman, Rowhani-Rahbar, Ali, Sagar, Rajesh, Salama, Joseph S, Sartorius, Benn, Seedat, Soraya, Sharew, Nigussie Tadesse, Singh, Jasvinder A, Sisay, Mekonnen, Skirbekk, Vegard, Stein, Dan J, Sufiyan, Mu’awiyyah Babale, Tabarés-Seisdedos, Rafael, Ukwaja, Kingsley Nnanna, Vasankari, Tommi Juhani, Younis, Mustafa Z, Zaidi, Zoubida, Hay, Simon I, Lopez, Alan D, Mokdad, Ali H, Vos, Theo, Murray, Christopher J. L

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Global, regional, and national consumption levels of dietary fats and oils in 1990 and 2010: a systematic analysis including 266 country-specific nutrition surveys von Micha, Renata, Khatibzadeh, Shahab, Shi, Peilin, Fahimi, Saman, Lim, Stephen, Andrews, Kathryn G, Engell, Rebecca E, Powles, John, Ezzati, Majid, Mozaffarian, Dariush

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Global and regional hearing impairment prevalence: an analysis of 42 studies in 29 countries von Stevens, Gretchen, Flaxman, Seth, Brunskill, Emma, Mascarenhas, Maya, Mathers, Colin D, Finucane, Mariel

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