Integration of fingerprint-based similarity searching and kernel-based partial least squares analysis to predict inhibitory activity against CSK, HER2, JAK1, JAK2, and JAK3 von Deokar, Hemantkumar, Deokar, Mrunalini, Buolamwini, John K.

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A small-molecule inhibitor of MDMX activates p53 and induces apoptosis von Wang, Hongbo, Ma, Xujun, Ren, Shumei, Buolamwini, John K, Yan, Chunhong

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Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter fu... von Wang, Chunmei, Lin, Wenwei, Playa, Hilaire, Sun, Shan, Cameron, Keyuna, Buolamwini, John K.

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The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models von Wang, Wei, Qin, Jiang-Jiang, Voruganti, Sukesh, Srivenugopal, Kalkunte S., Nag, Subhasree, Patil, Shivaputra, Sharma, Horrick, Wang, Ming-Hai, Wang, Hui, Buolamwini, John K, Zhang, Ruiwen

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Small Molecule Induces Time‐Dependent Inhibition of Stat3 Dimerization and DNA‐Binding Activity and Regresses Human Breast Tumor Xenografts von Yue, Peibin, Chen, Yue, Ogese, Monday O., Sun, Shan, Zhang, Xiaolei, Esan, Taiwo, Buolamwini, John K., Turkson, James

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SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo von Wang, Yinan, Yang, Chuanhe, Sims, Michelle M., Sacher, Joshua R., Raje, Mithun, Deokar, Hemantkumar, Yue, Peibin, Turkson, James, Buolamwini, John K., Pfeffer, Lawrence M.

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Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors von Sharma, Horrick, Patil, Shivaputra, Sanchez, Tino W., Neamati, Nouri, Schinazi, Raymond F., Buolamwini, John K.

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Targeting EGFR and HER-2 receptor tyrosine kinases for cancer drug discovery and development von Kamath, Shantaram, Buolamwini, John K.

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JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21 von Yang, Xinyi, Wang, Wei, Qin, Jiang-Jiang, Wang, Ming-Hai, Sharma, Horrick, Buolamwini, John K, Wang, Hui, Zhang, Ruiwen

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Identification of a New Class of MDM2 Inhibitor That Inhibits Growth of Orthotopic Pancreatic Tumors in Mice von Wang, Wei, Qin, Jiang-Jiang, Voruganti, Sukesh, Wang, Ming-Hai, Sharma, Horrick, Patil, Shivaputra, Zhou, Jianwei, Wang, Hui, Mukhopadhyay, Debabrata, Buolamwini, John K, Zhang, Ruiwen

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A novel RNA variant of human concentrative nucleoside transporter 1 (hCNT1) that is a potential cancer biomarker von Wang, Chunmei, Buolamwini, John K

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QSAR studies of new pyrido[3,4-b]indole derivatives as inhibitors of colon and pancreatic cancer cell proliferation von Deokar, Hemantkumar, Deokar, Mrunalini, Wang, Wei, Zhang, Ruiwen, Buolamwini, John K.

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Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy von Qin, Jiang-Jiang, Wang, Wei, Li, Xin, Deokar, Hemantkumar, Buolamwini, John K, Zhang, Ruiwen

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Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors von Sharma, Horrick, Sanchez, Tino W., Neamati, Nouri, Detorio, Mervi, Schinazi, Raymond F., Cheng, Xiaolin, Buolamwini, John K.

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Homology Model-Guided 3D-QSAR Studies of HIV-1 Integrase Inhibitors von Sharma, Horrick, Cheng, Xiaolin, Buolamwini, John K

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Synthesis and biological evaluation of novel 5( H)-phenanthridin-6-ones, 5( H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase i... von Patil, Shivaputra, Kamath, Shantaram, Sanchez, Tino, Neamati, Nouri, Schinazi, Raymond F., Buolamwini, John K.

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Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action von Punganuru, Surendra R, Artula, Viswanath, Zhao, Wei, Rajaei, Mehrdad, Deokar, Hemantkumar, Zhang, Ruiwen, Buolamwini, John K, Srivenugopal, Kalkunte S, Wang, Wei

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CoMFA and CoMSIA 3D QSAR and Docking Studies on Conformationally-Restrained Cinnamoyl HIV-1 Integrase Inhibitors:  Exploration of a Binding Mode at the Active Site von Buolamwini, John K, Assefa, Haregewein

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Design, Synthesis, and Evaluation of 2-Diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein Conjugat... von Lin, Wenwei, Buolamwini, John K

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Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action von Wang, Wei, Wang, Xinjie, Rajaei, Mehrdad, Youn, Ji Youn, Zafar, Atif, Deokar, Hemantkumar, Buolamwini, John K, Yang, Jianhua, Foster, Jennifer H, Zhou, Jia, Zhang, Ruiwen

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