Structural characterization of human galectin‐4 C‐terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antig... von Bum‐Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J, Blanchard, Helen

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Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation von Bum‐Erdene, Khuchtumur, Ghozayel, Mona K., Xu, David, Meroueh, Samy O.

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Small‐Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection von Xu, David, Bum‐Erdene, Khuchtumur, Leth, Julie M., Ghozayel, Mona K., Ploug, Michael, Meroueh, Samy O.

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Exploring Covalent Bond Formation at Tyr‐82 for Inhibition of Ral GTPase Activation von Landgraf, Alexander D., Yeh, I‐Ju, Ghozayel, Mona K., Bum‐Erdene, Khuchtumur, Gonzalez‐Gutierrez, Giovanni, Meroueh, Samy O.

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Chemical Space Overlap with Critical Protein–Protein Interface Residues in Commercial and Specialized Small‐Molecule Libraries von Si, Yubing, Xu, David, Bum‐Erdene, Khuchtumur, Ghozayel, Mona K., Yang, Baocheng, Clemons, Paul A., Meroueh, Samy O.

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Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia von Tarighat, Somayeh S, Fei, Fei, Joo, Eun Ji, Abdel-Azim, Hisham, Yang, Lu, Geng, Huimin, Bum-Erdene, Khuchtumur, Grice, I Darren, von Itzstein, Mark, Blanchard, Helen, Heisterkamp, Nora

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Mimicking Intermolecular Interactions of Tight Protein–Protein Complexes for Small‐Molecule Antagonists von Xu, David, Bum‐Erdene, Khuchtumur, Si, Yubing, Zhou, Donghui, Ghozayel, Mona K., Meroueh, Samy O.

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Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin-3-Specific Inhibitors von Bum-Erdene, Khuchtumur, Gagarinov, Ivan A., Collins, Patrick M., Winger, Moritz, Pearson, Andrew G., Wilson, Jennifer C., Leffler, Hakon, Nilsson, Ulf J., Grice, I. Darren, Blanchard, Helen

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Exploring a structural protein-drug interactome for new therapeutics in lung cancer von Peng, Xiaodong, Wang, Fang, Li, Liwei, Bum-Erdene, Khuchtumur, Xu, David, Wang, Bo, Sinn, Anthony A, Pollok, Karen E, Sandusky, George E, Li, Lang, Turchi, John J, Jalal, Shadia I, Meroueh, Samy O

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Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction von Bum-Erdene, Khuchtumur, Zhou, Donghui, Gonzalez-Gutierrez, Giovanni, Ghozayel, Mona K., Si, Yubing, Xu, David, Shannon, Harlan E., Bailey, Barbara J., Corson, Timothy W., Pollok, Karen E., Wells, Clark D., Meroueh, Samy O.

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Galectin-3 Interactions with Glycosphingolipids von Collins, Patrick M., Bum-Erdene, Khuchtumur, Yu, Xing, Blanchard, Helen

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Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases von Bum-Erdene, Khuchtumur, Liu, Degang, Gonzalez-Gutierrez, Giovanni, Ghozayel, Mona K., Xu, David, Meroueh, Samy O.

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Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists von Bum-Erdene, Khuchtumur, Yeh, I-Ju, Gonzalez-Gutierrez, Giovanni, Ghozayel, Mona K., Pollok, Karen, Meroueh, Samy O.

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Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling von Brenner, Robert J, Landgraf, Alexander D, Bum-Erdene, Khuchtumur, Gonzalez-Gutierrez, Giovanni, Meroueh, Samy O

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Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose and 2′-fucosyllactose von Bum-Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J., Blanchard, Helen

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Novel Selective Galectin‑3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia von Bum-Erdene, Khuchtumur, Collins, Patrick M, Hugo, Matthew W, Tarighat, Somayeh S, Fei, Fei, Kishor, Chandan, Leffler, Hakon, Nilsson, Ulf. J, Groffen, John, Grice, I. Darren, Heisterkamp, Nora, Blanchard, Helen

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Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction von Bum-Erdene, Khuchtumur, Ghozayel, Mona K, Zhang, Mark J, Gonzalez-Gutierrez, Giovanni, Meroueh, Samy O

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Design and Synthesis of Fragment Derivatives with a Unique Inhibition Mechanism of the uPAR·uPA Interaction von Bum-Erdene, Khuchtumur, Liu, Degang, Xu, David, Ghozayel, Mona K, Meroueh, Samy O

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Mimicking Native Interactions for Small-Molecule Inhibitors of Tight Protein-Protein Interactions von Xu, David, Bum-Erdene, Khuchtumur, Si, Yubing, Zhou, Donghui, Liu, Degang, Ghozayel, Mona, Meroueh, Samy

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Galectin-3 Inhibition As a Novel Therapeutic Approach in Acute Lymphoblastic Leukemia (ALL) von Samadzadeh Tarighat, Somayeh, Fei, Fei, Bum-Erdene, Khuchtumur, Blanchard, Helen, Groffen, John, Heisterkamp, Nora

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