DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice von Meira, Lisiane B, Bugni, James M, Green, Stephanie L, Lee, Chung-Wei, Pang, Bo, Borenshtein, Diana, Rickman, Barry H, Rogers, Arlin B, Moroski-Erkul, Catherine A, McFaline, Jose L, Schauer, David B, Dedon, Peter C, Fox, James G, Samson, Leona D

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Diet-induced obesity promotes colon tumor development in azoxymethane-treated mice von Tuominen, Iina, Al-Rabadi, Leina, Stavrakis, Dimitris, Karagiannides, Iordanis, Pothoulakis, Charalabos, Bugni, James M

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DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice von Albertson, Tina M, Ogawa, Masanori, Bugni, James M, Hays, Laura E, Chen, Yang, Wang, Yanping, Treuting, Piper M, Heddle, John A, Goldsby, Robert E, Preston, Bradley D

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Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression von Wang, Yufang, Velho, Sérgia, Vakiani, Efsevia, Peng, Shouyong, Bass, Adam J, Chu, Gerald C, Gierut, Jessica, Bugni, James M, Der, Channing J, Philips, Mark, Solit, David B, Haigis, Kevin M

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Genomic predictors of interindividual differences in response to DNA damaging agents von Fry, Rebecca C, Svensson, J Peter, Valiathan, Chandni, Wang, Emma, Hogan, Brad J, Bhattacharya, Sanchita, Bugni, James M, Whittaker, Charles A, Samson, Leona D

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The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer von Bugni, James M., Rabadi, Leina Al, Jubbal, Kevin, Karagiannides, Iordanis, Lawson, Gregory, Pothoulakis, Charalabos

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Substance P (SP)-Neurokinin-1 Receptor (NK-1R) Alters Adipose Tissue Responses to High-Fat Diet and Insulin Action von Karagiannides, Iordanes, Stavrakis, Dimitris, Bakirtzi, Kyriaki, Kokkotou, Efi, Pirtskhalava, Tamara, Nayeb-Hashemi, Hamed, Bowe, Collin, Bugni, James M, Nuño, Miriam, Lu, Bao, Gerard, Norma P, Leeman, Susan E, Kirkland, James L, Pothoulakis, Charalabos

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604 Identification of a NK-1R Antagonist as a Novel Therapeutic Approach in Colon Cancer by High Throughput Chemical Screening von Polytarchou, Christos, Palumbo, Tiziana, Bugni, James M, Pothoulakis, Charalabos, Iliopoulos, Dimitrios

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Mo1609 Obesity Drives Colon Tumor Development in AOM-Treated Mice von Bugni, James M, Rabadi, Leina Al, Stavrakis, Dimitris, Karagiannidis, Iordanis, Pothoulakis, Charalabos

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The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility von Bugni, James M., Poole, Therese M., Drinkwater, Norman R.

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T1174 The Neurotensin Receptor-1 Promotes Tumor Development in a Sporadic but Not an Inflammation-Associated Mouse Model of Colorectal Cancer von Bugni, James M, Karagiannidis, Iordanis, Pothoulakis, Charalabos

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Colitis-Associated Adipose Tissue Responses to Corticotropin-Releasing Hormone Family of Neuropeptides von Fink, Christopher, Karagiannidis, Iordanis, Bakirtzi, Kyriaki, Bugni, James M, Pothoulakis, Charalabos

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Neurotensin (NT) Receptor 1 (Ntr1)-MicroRNA Networks in Human Colon Epithelial Cells. Characterization of Novel Pathways Connecting Neurotensin and Tumor Growth von Bakirtzi, Kyriaki, Iliopoulos, Dimitrios, Karagiannidis, Iordanis, Bugni, James M, Hatziapostolou, Maria, Pothoulakis, Charalabos

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Genetic association and functional studies of major polymorphic variants of MGMT von Bugni, James M., Han, Jiali, Tsai, Miaw-sheue, Hunter, David J., Samson, Leona D.

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Obesity in the Absence of High Fat Diet Enhances Tumor Development in AOM-Treated Mice von Bugni, James M, Al Rabadi, Leina, Stavrakis, Dimitris G, Jubbal, Kevin, Karagiannidis, Iordanis, Pothoulakis, Charalabos

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W1856 Neurokinin-1receptor (NK-1r) Deficiency is Associated With Reduced Weight Gain and Improved Glucose Metabolic Responses in Mice von Karagiannidis, Iordanis, Stavrakis, Dimitris G, Kokkotou, Efi, Kyriaki, Bakirtzi, Nayeb-Hashemi, Hamed, Bowe, Collin, Bugni, James M, Pothoulakis, Charalabos

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M2005 Truncated Neurokinin-1 Receptor Mediates Colon Cancer Development von Koon, Hon Wai, Bugni, James M, Zhao, Dezheng, Kumar, Aatish, Xu, Hua, Pothoulakis, Charalabos

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S1651 Effects of Diet Induced Obesity in the Outcome of Experimental Colitis in C57BL/6 Mice von Karagiannidis, Iordanis, Bowe, Collin, Koon, Hon Wai, Bugni, James M, Stavrakis, Dimitris G, Pothoulakis, Charalabos

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Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins von Bugni, J M, Meira, L B, Samson, L D

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Polymerase delta and epsilon proofreading cooperate with MMR to suppress lethal mutations and cancer in mice von Albertson, Tina M., Hays, Laura E., Bugni, James M., Ogawa, Masanori, Treuting, Piper M., Goldsby, Robert E., Preston, Bradley D.

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