Concordance of preclinical and clinical pharmacology and toxicology of monoclonal antibodies and fusion proteins: soluble targets von Martin, Pauline L, Bugelski, Peter J

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Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets von Bugelski, Peter J, Martin, Pauline L

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Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α von Shealy, David J., Cai, Ann, Staquet, Kim, Baker, Audrey, Lacy, Eilyn R., Johns, Laura, Vafa, Omid, Gunn, George, Tam, Susan, Sague, Sarah, Wang, Dana, Brigham-Burke, Mike, Dalmonte, Paul, Emmell, Eva, Pikounis, Bill, Bugelski, Peter J., Zhou, Honghui, Scallon, Bernard J., Giles-Komar, Jill M.

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Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice von Stowell, Nicole C, Seideman, Jonathan, Raymond, Holly A, Smalley, Karen A, Lamb, Roberta J, Egenolf, Devon D, Bugelski, Peter J, Murray, Lynne A, Marsters, Paul A, Bunting, Rachel A, Flavell, Richard A, Alexopoulou, Lena, San Mateo, Lani R, Griswold, Don E, Sarisky, Robert T, Mbow, M Lamine, Das, Anuk M

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Anti‐interleukin‐6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus von Liang, Bailin, Gardner, Debra B., Griswold, Don E., Bugelski, Peter J., Song, Xiao Yu R.

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Critical Review of Preclinical Approaches to Evaluate the Potential of Immunosuppressive Drugs to Influence Human Neoplasia von Bugelski, Peter J., Volk, Amy, Walker, Mindi R., Krayer, John H., Martin, Pauline, Descotes, Jacques

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Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys von Hart, Timothy K., Cook, Richard M., Zia-Amirhosseini, Parnian, Minthorn, Elisabeth, Sellers, Teresa S., Maleeff, Beverly E., Eustis, Scot, Schwartz, Lester W., Tsui, Ping, Appelbaum, Edward R., Martin, Elise C., Bugelski, Peter J., Herzyk, Danuta J.

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Genetic aspects of immune-mediated adverse drug effects von Bugelski, Peter J

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Monoclonal antibody-induced cytokine-release syndrome von Bugelski, Peter J, Achuthanandam, Ram, Capocasale, Renold J, Treacy, George, Bouman-Thio, Esther

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CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools von Sathyanarayana, Pradeep, Houde, Estelle, Marshall, Deborah, Volk, Amy, Makropoulos, Dorie, Emerson, Christine, Pradeep, Anamika, Bugelski, Peter J., Wojchowski, Don M.

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Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model von BERMAN, Dora M, CABRERA, Over, HORNINGER, Denison, LARK, Michael, DAVIS, Janet E, ALEJANDRO, Rodolfo, BERGGREN, Per-Olof, ZIMMERMAN, Mark, O'NEIL, John J, RICORDI, Camillo, KENYON, Norma S, KENYAN, Norman M, MILLER, Joshua, TAM, Susan H, KHANDEKAR, Vrinda S, PICHA, Kristen M, SODERMAN, Avery R, JORDAN, Robert E, BUGELSKI, Peter J

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Immunomodulatory Effects of Anti-CD4 Antibody in Host Resistance against Infections and Tumors in Human CD4 Transgenic Mice von HERZYK, Danuta J, GORE, Elizabeth R, POLSKY, Rodd, NADWODNY, Kimberly L, MAIER, Curtis C, LIU, Susan, HART, Timothy K, HARMSEN, Allen G, BUGELSKI, Peter J

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Development of a human whole blood assay for prediction of cytokine release similar to anti-CD28 superagonists using multiplex cytokine and hierarchical cluster analysis von Walker, Mindi R., Makropoulos, Dorie A., Achuthanandam, Ram, Van Arsdell, Scott, Bugelski, Peter J.

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Immunotoxicologic effects of cyclosporine on tumor progression in models of squamous cell carcinoma and B-cell lymphoma in C3H mice von Rafferty, Patricia, Egenolf, Devon, Brosnan, Kerry, Makropoulos, Dorie, Jordan, Jarrat, Meshaw, Kay, Walker, Mindi, Volk, Amy, Bugelski, Peter J.

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Effects of CNTO 530, an erythropoietin mimetic-IgG4 fusion protein, on embryofetal development in rats and rabbits von Martin, Pauline L., Sachs, Clifford, Hoberman, Alan, Jiao, Qun, Bugelski, Peter J.

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Development of a murine model of lymph node metastases suitable for immunotoxicity studies von Egenolf, Devon D., Rafferty, Patricia, Brosnan, Kerry, Walker, Mindi, Jordan, Jarrat, Makropoulos, Dorie, Kavalkovich, Karl, Watson, Sharon, Johns, Laura, Volk, Amy, Bugelski, Peter J.

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Pharmacodynamics of Recombinant Human Erythropoietin in Murine Bone Marrow von Bugelski, Peter J., Nesspor, Thomas, Volk, Amy, O’Brien, Joanne, Makropoulos, Dorie, Shamberger, Kim, Fisher, Paul W., James, Ian, Graden, Danielle, Capocasale, Renold J.

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A Novel Technique For Mapping the Lipid Composition of Atherosclerotic Fatty Streaks by En Face Fluorescence Microscopy von Klinkner, Anne M, Bugelski, Peter J, Waites, C. Robbie, Louden, Calvert, Hart, Timothy K, Kerns, William D

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A statistical pattern recognition approach for determining cellular viability and lineage phenotype in cultured cells and murine bone marrow von Quinn, John, Fisher, Paul W., Capocasale, Renold J., Achuthanandam, Ram, Kam, Moshe, Bugelski, Peter J., Hrebien, Leonid

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T-Dependent Antigen Response (TDAR) Tests: Meta-Analysis of Results Generated Across Multiple Laboratories von Bugelski, Peter J., Kim, Carin

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