The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes von Buelow, Ben, Song, Yumei, Scharenberg, Andrew M.

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Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion von Paddock, Marcia N, Buelow, Ben D, Takeda, Shunichi, Scharenberg, Andrew M

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The BRCT domain of PARP-1 is required for immunoglobulin gene conversion von Paddock, Marcia N, Buelow, Ben D, Takeda, Shunichi, Scharenberg, Andrew M

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Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release von Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali

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A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer von Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Lewis Wilson, Kristin, Malik-Chaudhry, Harbani K., Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Yabut, Rodolfovan D., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.

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S224: HIGH COMPLETE RESPONSE RATE WITH TNB‐486, A NOVEL CD19XCD3 T‐CELL ENGAGER, IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: INTERIM RESULTS FROM AN ONGOING PHASE 1 STUDY von Jacobs, Ryan, Nair, Ranjit, Cho, Seok‐Goo, Devata, Sumana, Gaballa, Sameh, Yoon, Dok Hyun, Stevens, Don, Kim, Jin Seok, Shah, Nirav N, Brennan, Denise Marie, Law, Jason, Lesley, Robin, Chen, Rob, Forcina, Alessandra, Buelow, Ben, Hou, Jing‐Zhou

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Ex vivo efficacy of BCMA‐bispecific antibody TNB‐383B in relapsed/refractory multiple myeloma von Foureau, David M., Bhutani, Manisha, Robinson, Myra, Guo, Fei, Pham, Duy, Buelow, Ben, Steuerwald, Nury, Rigby, Katherine, Tjaden, Elise, Leonidas, Marina, Paul, Barry A., Atrash, Shebli, Ndiaye, Ami, Symanowski, James T., Voorhees, Peter M., Usmani, Saad Z.

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Characterization of parameters required for effective use of tamoxifen-regulated recombination von Buelow, Ben, Scharenberg, Andrew M

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Fusobacterium Liver Abscess von Buelow, Ben D., Lambert, Joelle M., Gill, Ryan M.

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Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation von Buelow, Ben, Uzunparmak, Burak, Paddock, Marcia, Scharenberg, Andrew M

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A Phase I First-in-Human Study of ABBV-383, a B-Cell Maturation Antigen × CD3 Bispecific T-Cell Redirecting Antibody, in Patients With Relapsed/Refractory Multiple Myeloma von D'Souza, Anita, Shah, Nina, Rodriguez, Cesar, Voorhees, Peter M, Weisel, Katja, Bueno, Orlando F, Pothacamury, Rajvineeth K, Freise, Kevin J, Yue, Susan, Ross, Jeremy A, Polepally, Akshanth R, Talati, Chetasi, Lee, Shane, Jin, Ziyi, Buelow, Ben, Vij, Ravi, Kumar, Shaji

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Initial Results of a Phase I Study of TNB-383B, a BCMA x CD3 Bispecific T-Cell Redirecting Antibody, in Relapsed/Refractory Multiple Myeloma von Rodriguez, Cesar, D'Souza, Anita, Shah, Nina, Voorhees, Peter M., Buelow, Ben, Vij, Ravi, Kumar, Shaji K.

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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Interim Results of the Phase 1 Study of Tnb-486, a Novel CD19xCD3 T-Cell Engager, in Patients with Relapsed/Refractory (R/R) B-NHL von Hou, Jing-Zhou, Jacobs, Ryan, Cho, Seok-Goo, Devata, Sumana, Gaballa, Sameh, Yoon, Dok Hyun, Stevens, Don A., Kim, Jin Seok, Buelow, Ben, Nair, Ranjit

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Double Step-up Dosing (2SUD) Regimen Mitigates Severe Icans and CRS While Maintaining High Efficacy in Subjects with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL) Tre... von Gaballa, Sameh, Nair, Ranjit, Jacobs, Ryan W, Devata, Sumana, Cho, Seok-Goo, Stevens, Don A., Yoon, Dok Hyun, Shah, Nirav N., Brennan, Denise, Law, Jason, Chen, Robert, Sermer, David, Lesley, Robin, Buelow, Ben, Forcina, Alessandra, Hou, Jing-Zhou

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High complete response rate with TNB-486 in relapsed/refractory follicular lymphoma: Interim results from an ongoing phase 1 study von Nair, Ranjit, Jacobs, Ryan, Cho, Seok-Goo, Devata, Sumana, Gaballa, Sameh, Yoon, Dok Hyun, Stevens, Don A., Kim, Jin Seok, Shah, Nirav Niranjan, Brennan, Denise Marie, Law, Jason, Chen, Rob, Forcina, Alessandra, Buelow, Ben, Hou, Jing-Zhou

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TNB585.001: A multicenter, phase 1, open-label, dose-escalation and expansion study of tnb-585, a bispecific T-cell engager targeting PSMA in subjects with metastatic castrate resi... von Buelow, Ben, Dalvi, Pranjali, Dang, Kevin, Patel, Ashwin, Johal, Kiran, Pham, Duy, Panchal, Shailee, Liu, Yvonne, Fong, Lawrence, Sartor, A. Oliver, McKean, Meredith, Schellenberger, Ute, Iyer, Suhasini

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Requirements for DNA Unpairing during Displacement Synthesis by HIV-1 Reverse Transcriptase von Winshell, Jamie, Paulson, Benjamin A., Buelow, Ben D., Champoux, James J.

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TNB383B.0001: A Multicenter, Phase 1, Open-Label, Dose-Escalation Andexpansion Study of TNB-383B, a Bispecific Antibodytargeting BCMA in Subjects with Relapsed or Refractorymultipl... von Buelow, Ben, D'Souza, Anita, Rodriguez, Cesar, Vij, Ravi, Nath, Rajneesh, Snyder, Melinda, Pham, Duy, Patel, Ashwin, Iyer, Suhasini

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A Phase 1 First-in-Human Study of Tnb-383B, a BCMA x CD3 Bispecific T-Cell Redirecting Antibody, in Patients with Relapsed/Refractory Multiple Myeloma von Kumar, Shaji, D'Souza, Anita, Shah, Nina, Rodriguez, Cesar, Voorhees, Peter M., Bueno, Orlando F., Buelow, Ben, Freise, Kevin J., Yue, Susan, Pothacamury, Rajvineeth Kumar, Polepally, Akshanth R., Vij, Ravi

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