Extracellular Vesicles from Red Blood Cells and Their Evolving Roles in Health, Coagulopathy and Therapy von Thangaraju, Kiruphagaran, Neerukonda, Sabari Nath, Katneni, Upendra, Buehler, Paul W.

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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins von Schaer, Dominik J., Buehler, Paul W., Alayash, Abdu I., Belcher, John D., Vercellotti, Gregory M.

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Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients von Thomas, Tiffany, Stefanoni, Davide, Dzieciatkowska, Monika, Issaian, Aaron, Nemkov, Travis, Hill, Ryan C, Francis, Richard O, Hudson, Krystalyn E, Buehler, Paul W, Zimring, James C, Hod, Eldad A, Hansen, Kirk C, Spitalnik, Steven L, D’Alessandro, Angelo

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Hemoglobin-based oxygen carriers: from mechanisms of toxicity and clearance to rational drug design von Buehler, Paul W, D’Agnillo, Felice, Schaer, Dominik J

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Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma von Setua, Saini, Thangaraju, Kiruphagaran, Dzieciatkowska, Monika, Wilkerson, Rebecca B., Nemkov, Travis, Lamb, Derek R., Tagaya, Yutaka, Boyer, Tori, Rowden, Tobi, Doctor, Allan, D’Alessandro, Angelo, Buehler, Paul W.

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Sex-dependent balance between thrombin and plasmin generation in the presence of thrombomodulin von Tarandovskiy, Ivan D., Buehler, Paul W., Karnaukhova, Elena

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Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and β‑Thalassemia Mice von Lisk, Christina, Cendali, Francesca, Setua, Saini, Thangaraju, Kiruphararan, Pak, David I., Swindle, Delaney, Dzieciatkowska, Monika, Gamboni, Fabia, Hassell, Kathryn, Nuss, Rachelle, George, Gemlyn, Davizon-Castillo, Pavel, Buehler, Paul W., D’Alessandro, Angelo, Irwin, David C.

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Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage von Stefanoni, Davide, Shin, Hye Kyung H., Baek, Jin Hyen, Champagne, Devin P., Nemkov, Travis, Thomas, Tiffany, Francis, Richard O., Zimring, James C., Yoshida, Tatsuro, Reisz, Julie A., Spitalnik, Steven L., Buehler, Paul W., D'Alessandro, Angelo

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Magnetophoretic and spectral characterization of oxyhemoglobin and deoxyhemoglobin: Chemical versus enzymatic processes von Weigand, Mitchell R. H., Gomez-Pastora, Jenifer, Kim, James, Kurek, Matthew T., Hickey, Richard J., Irwin, David C., Buehler, Paul W., Zborowski, Maciej, Palmer, Andre F., Chalmers, Jeffrey J.

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Human Plasma and Recombinant Hemopexins: Heme Binding Revisited von Karnaukhova, Elena, Owczarek, Catherine, Schmidt, Peter, Schaer, Dominik J., Buehler, Paul W.

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The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study von Belcher, Donald A, Ju, Julia A, Baek, Jin Hyen, Yalamanoglu, Ayla, Buehler, Paul W, Gilkes, Daniele M, Palmer, Andre F

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C1-inhibitor influence on platelet activation by thrombin receptors agonists von Tarandovskiy, Ivan D., Buehler, Paul W., Karnaukhova, Elena

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Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics von Vallelian, Florence, Buehler, Paul W., Schaer, Dominik J.

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ZOOMICS: Comparative Metabolomics of Red Blood Cells From Guinea Pigs, Humans, and Non-human Primates During Refrigerated Storage for Up to 42 Days von Bertolone, Lorenzo, Shin, Hye Kyung H, Baek, Jin Hyen, Gao, Yamei, Spitalnik, Steven L, Buehler, Paul W, D'Alessandro, Angelo

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Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification von Buehler, Paul W., Abraham, Bindu, Vallelian, Florence, Linnemayr, Charlotte, Pereira, Claudia P., Cipollo, John F., Jia, Yiping, Mikolajczyk, Malgorzata, Boretti, Felicitas S., Schoedon, Gabriele, Alayash, Abdu I., Schaer, Dominik J.

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Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs von Boretti, Felicitas S, Buehler, Paul W, D'Agnillo, Felice, Kluge, Katharina, Glaus, Tony, Butt, Omer I, Jia, Yiping, Goede, Jeroen, Pereira, Claudia P, Maggiorini, Marco, Schoedon, Gabriele, Alayash, Abdu I, Schaer, Dominik J

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Metabolic correlates to critical speed in murine models of sickle cell disease von Cendali, Francesca I, Nemkov, Travis, Lisk, Christina, Lacroix, Ian S, Nouraie, Seyed-Mehdi, Zhang, Yingze, Gordeuk, Victor R, Buehler, Paul W, Irwin, David, D'Alessandro, Angelo

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CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin von Schaer, Dominik J., Schaer, Christian A., Buehler, Paul W., Boykins, Robert A., Schoedon, Gabriele, Alayash, Abdu I., Schaffner, Andreas

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Mechanical stimuli such as shear stress and piezo1 stimulation generate red blood cell extracellular vesicles von Sangha, Gurneet S, Weber, Callie M, Sapp, Ryan M, Setua, Saini, Thangaraju, Kiruphagaran, Pettebone, Morgan, Rogers, Stephen C, Doctor, Allan, Buehler, Paul W, Clyne, Alisa M

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Haptoglobin Therapeutics and Compartmentalization of Cell-Free Hemoglobin Toxicity von Buehler, Paul W., Humar, Rok, Schaer, Dominik J.

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