Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis von Dobie, Ross, Wilson-Kanamori, John R., Henderson, Beth E.P., Smith, James R., Matchett, Kylie P., Portman, Jordan R., Wallenborg, Karolina, Picelli, Simone, Zagorska, Anna, Pendem, Swetha V., Hudson, Thomas E., Wu, Minnie M., Budas, Grant R., Breckenridge, David G., Harrison, Ewen M., Mole, Damian J., Wigmore, Stephen J., Ramachandran, Prakash, Ponting, Chris P., Teichmann, Sarah A., Marioni, John C., Henderson, Neil C.

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Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function von Huang, Qunhua, Zhou, Huanjiao Jenny, Zhang, Haifeng, Huang, Yan, Hinojosa-Kirschenbaum, Ford, Fan, Peidong, Yao, Lina, Belardinelli, Luiz, Tellides, George, Giordano, Frank J, Budas, Grant R, Min, Wang

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Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart von Chen, Che-Hong, Budas, Grant R, Churchill, Eric N, Disatnik, Marie-Hélène, Hurley, Thomas D, Mochly-Rosen, Daria

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ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension von Budas, Grant R, Boehm, Mario, Kojonazarov, Baktybek, Viswanathan, Gayathri, Tian, Xia, Veeroju, Swathi, Novoyatleva, Tatyana, Grimminger, Friedrich, Hinojosa-Kirschenbaum, Ford, Ghofrani, Hossein A, Weissmann, Norbert, Seeger, Werner, Liles, John T, Schermuly, Ralph T

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease von Liles, John T, Corkey, Britton K, Notte, Gregory T, Budas, Grant R, Lansdon, Eric B, Hinojosa-Kirschenbaum, Ford, Badal, Shawn S, Lee, Michael, Schultz, Brian E, Wise, Sarah, Pendem, Swetha, Graupe, Michael, Castonguay, Laurie, Koch, Keith A, Wong, Melanie H, Papalia, Giuseppe A, French, Dorothy M, Sullivan, Theodore, Huntzicker, Erik G, Ma, Frank Y, Nikolic-Paterson, David J, Altuhaifi, Tareq, Yang, Haichun, Fogo, Agnes B, Breckenridge, David G

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Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury von Budas, Grant R., Churchill, Eric N., Mochly-Rosen, Daria

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The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model von Schwabl, Philipp, Hambruch, Eva, Budas, Grant R., Supper, Paul, Burnet, Michael, Liles, John T., Birkel, Manfred, Brusilovskaya, Ksenia, Konigshofer, Philipp, Peck-Radosavljevic, Markus, Watkins, William J., Trauner, Michael, Breckenridge, David G., Kremoser, Claus, Reiberger, Thomas

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Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice von Budas, Grant R, Disatnik, Marie-Hélène, Chen, Che-Hong, Mochly-Rosen, Daria

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Regulation and function of apoptosis signal-regulating kinase 1 in rheumatoid arthritis von Nygaard, Gyrid, Di Paolo, Julie A., Hammaker, Deepa, Boyle, David L., Budas, Grant, Notte, Gregory T., Mikaelian, Igor, Barry, Vivian, Firestein, Gary S.

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PKC Isozymes in Chronic Cardiac Disease : Possible Therapeutic Targets? von CHURCHILL, Eric, BUDAS, Grant, VALLENTIN, Alice, KOYANAGI, Tomoyoshi, MOCHLY-ROSEN, Daria

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Intracellular Na+ overload causes oxidation of CaMKII and leads to Ca2+ mishandling in isolated ventricular myocytes von Viatchenko-Karpinski, Serge, Kornyeyev, Dmytro, El-Bizri, Nesrine, Budas, Grant, Fan, Peidong, Jiang, Zhan, Yang, Jin, Anderson, Mark E., Shryock, John C., Chang, Ching-Pin, Belardinelli, Luiz, Yao, Lina

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Aldehyde Dehydrogenase 2 in Cardiac Protection: A New Therapeutic Target? von Budas, Grant R, Disatnik, Marie-Hélène, Mochly-Rosen, Daria

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Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice von Sun, Xiaoyun, Budas, Grant R., Xu, Lijun, Barreto, George E., Mochly-Rosen, Daria, Giffard, Rona G.

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Activation of PKC epsilon-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice von Martins, Barbara B., Hosch, Natalia G., Alcantara, Queren A., Budas, Grant R., Chen, Che-Hong, Mochly-Rosen, Daria, Ferreira, Julio C. B., Zambelli, Vanessa O.

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ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model von Schuster-Gaul, Susanne, Geisler, Lukas Jonathan, McGeough, Matthew D., Johnson, Casey D., Zagorska, Anna, Li, Li, Wree, Alexander, Barry, Vivian, Mikaelian, Igor, Jih, Lily J., Papouchado, Bettina G., Budas, Grant, Hoffman, Hal M., Feldstein, Ariel E.

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Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2-/- mouse model of sclerosing cholangitis von Fuchs, Claudia D., Sroda, Natalie, Scharnagl, Hubert, Gupta, Ruchi, Minto, Wesley, Stojakovic, Tatjana, Liles, John T., Budas, Grant, Hollenback, David, Trauner, Michael

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Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension von Wilson, Kathryn S., Buist, Hanna, Suveizdyte, Kornelija, Liles, John T., Budas, Grant R., Hughes, Colin, MacLean, Margaret R., Johnson, Martin, Church, Alistair C., Peacock, Andrew J., Welsh, David J.

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Hypoxia‐induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channels von Budas, Grant R., Jovanovic, Sofija, Crawford, Russell M., Jovanovic, Aleksandar

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Overexpression of SUR2A generates a cardiac phenotype resistant to ischemia von Du, Qingyou, Jovanović, Sofija, Clelland, Allyson, Sukhodub, Andrey, Budas, Grant, Phelan, Karen, Murray-Tait, Victoria, Malone, Lorraine, Jovanović, Aleksandar

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Identification of εPKC Targets During Cardiac Ischemic Injury von Budas, Grant, Costa, Helio Miranda, Jr, Ferreira, Julio Cesar Batista, André Teixeira da Silva Ferreira, Perales, Jonas, Krieger, José Eduardo, Mochly-Rosen, Daria, Schechtman, Deborah

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