Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase von BUCKNER, F. S, VERLINDE, C. L. M. J, LA FLAMME, A. C, VAN VOORHUIS, W. C

Volltext

Adenosine Analogues as Selective Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosomatidae via Structure-Based Drug Design von Bressi, Jerome C, Verlinde, Christophe L. M. J, Aronov, Alex M, Shaw, My Le, Shin, Sam S, Nguyen, Lisa N, Suresh, Stephen, Buckner, Frederick S, Van Voorhis, Wesley C, Kuntz, Irwin D, Hol, Wim G. J, Gelb, Michael H

Volltext

Potent Anti-Trypanosoma cruzi Activities of Oxidosqualene Cyclase Inhibitors von BUCKNER, Frederick S, GRIFFIN, John H, WILSON, Aaron J, VAN VOORHIS, Wesley C

Volltext

Cytomegalovirus Disease of the Gastrointestinal Tract in Patients Without AIDS von Buckner, Frederick S., Pomeroy, Claire

Volltext

Detection of Live Trypanosoma cruzi in Tissues of Infected Mice by Using Histochemical Stain for β-Galactosidase von BUCKNER, F. S, WILSON, A. J, VAN VOORHIS, W. C

Volltext

Induction of resistance to azole drugs in Trypanosoma cruzi von BUCKNER, F. S, WILSON, A. J, WHITE, T. C, VAN VOORHIS, W. C

Volltext

The Protein Farnesyltransferase Inhibitor Tipifarnib as a New Lead for the Development of Drugs against Chagas Disease von Hucke, Oliver, Gelb, Michael H, Verlinde, Christophe L. M. J, Buckner, Frederick S

Volltext

COLORIMETRIC ASSAY FOR SCREENING COMPOUNDS AGAINST LEISHMANIA AMASTIGOTES GROWN IN MACROPHAGES von BUCKNER, FREDERICK S, WILSON, AARON J

Volltext

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics von Gelb, Michael H., Van Voorhis, Wesley C., Buckner, Frederick S., Yokoyama, Kohei, Eastman, Richard, Carpenter, Elisabeth P., Panethymitaki, Chrysoula, Brown, Katherine A., Smith, Deborah F.

Volltext

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine von Bressi, J C, Choe, J, Hough, M T, Buckner, F S, Van Voorhis, W C, Verlinde, C L, Hol, W G, Gelb, M H

Volltext

Structure-Based Design of Submicromolar, Biologically Active Inhibitors of Trypanosomatid Glyceraldehyde-3-Phosphate Dehydrogenase von Aronov, Alex M., Suresh, Stephen, Buckner, Frederick S., Van Voorhis, Wesley C., Christophe L. M. J. Verlinde, Opperdoes, Fred R., Wim G. J. Hol, Gelb, Michael H.

Volltext

Leishmania major activates IL-1α expression in macrophages through a MyD88-dependent pathway von Hawn, Thomas R., Ozinsky, Adrian, Underhill, David M., Buckner, Frederick S., Akira, Shizuo, Aderem, Alan

Volltext

Hypertension Following Erythropoietin Therapy in Anemic Hemodialysis Patients von Buckner, Frederick S., Eschbach, Joseph W., Haley, N. Rebecca, Davidson, Robert C., Adamson, John W.

Volltext

Trypanosome and Animal Lanosterol Synthases Use Different Catalytic Motifs von Joubert, Bridget M, Buckner, Frederick S, Matsuda, Seiichi P. T

Volltext

Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kDa subunits as a new target for antiparasite therapeutics von Yokoyama, K. (University of Washington, Seattle, WA.), Trobridge, P, Buckner, F.S, Van Voorhis, W.C, Stuart, K.D, Gelb, M.H

Volltext

Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major von Buckner, Frederick S, Eastman, Richard T, Nepomuceno-Silva, José L, Speelmon, Emily C, Myler, Peter J, Van Voorhis, Wesley C, Yokoyama, Kohei

Volltext

Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei von Buckner, Frederick S., Yokoyama, Kohei, Nguyen, Lisa, Grewal, Anita, Erdjument-Bromage, Hediye, Tempst, Paul, Strickland, Corey L., Xiao, Li, Van Voorhis, Wesley C., Gelb, Michael H.

Volltext

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth von Yokoyama, Kohei, Trobridge, Patty, Buckner, Frederick S, Scholten, Jeffrey, Stuart, Kenneth D, Van Voorhis, Wesley C, Gelb, Michael H

Volltext

Trypanosoma cruzi:Use of Herpes Simplex Virus–Thymidine Kinase as a Negative Selectable Marker von Buckner, Frederick S., Wilson, Aaron J., Van Voorhis, Wesley C.

Volltext

444 DEVELOPMENT OF NEW DRUGS FOR CHAGAS DISEASE von Buckner, F. S., Kraus, J. M., Verlinde, C. L., Gelb, M. H., Hamilton, A. D.

Volltext