Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships von Wenglowsky, Steve, Ahrendt, Kateri A., Buckmelter, Alex J., Feng, Bainian, Gloor, Susan L., Gradl, Stefan, Grina, Jonas, Hansen, Joshua D., Laird, Ellen R., Lunghofer, Paul, Mathieu, Simon, Moreno, David, Newhouse, Brad, Ren, Li, Risom, Tyler, Rudolph, Joachim, Seo, Jeongbeob, Sturgis, Hillary L., Voegtli, Walter C., Wen, Zhaoyang

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Potent and Selective Aminopyrimidine-Based B-Raf Inhibitors with Favorable Physicochemical and Pharmacokinetic Properties von Mathieu, Simon, Gradl, Stefan N, Ren, Li, Wen, Zhaoyang, Aliagas, Ignacio, Gunzner-Toste, Janet, Lee, Wendy, Pulk, Rebecca, Zhao, Guiling, Alicke, Bruno, Boggs, Jason W, Buckmelter, Alex J, Choo, Edna F, Dinkel, Victoria, Gloor, Susan L, Gould, Stephen E, Hansen, Joshua D, Hastings, Gregg, Hatzivassiliou, Georgia, Laird, Ellen R, Moreno, David, Ran, Yingqing, Voegtli, Walter C, Wenglowsky, Steve, Grina, Jonas, Rudolph, Joachim

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Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-Raf(V600E) kinase with favorable physicochemical and pharmacokinetic properties von Ren, Li, Laird, Ellen R, Buckmelter, Alex J, Dinkel, Victoria, Gloor, Susan L, Grina, Jonas, Newhouse, Brad, Rasor, Kevin, Hastings, Gregg, Gradl, Stefan N, Rudolph, Joachim

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Non-oxime inhibitors of B-Raf(V600E) kinase von Ren, Li, Wenglowsky, Steve, Miknis, Greg, Rast, Bryson, Buckmelter, Alex J, Ely, Robert J, Schlachter, Stephen, Laird, Ellen R, Randolph, Nikole, Callejo, Michele, Martinson, Matthew, Galbraith, Sarah, Brandhuber, Barbara J, Vigers, Guy, Morales, Tony, Voegtli, Walter C, Lyssikatos, Joseph

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The Discovery of furo[2,3- c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors von Buckmelter, Alex J., Ren, Li, Laird, Ellen R., Rast, Bryson, Miknis, Greg, Wenglowsky, Steve, Schlachter, Stephen, Welch, Mike, Tarlton, Eugene, Grina, Jonas, Lyssikatos, Joseph, Brandhuber, Barbara J., Morales, Tony, Randolph, Nikole, Vigers, Guy, Martinson, Matthew, Callejo, Michele

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Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors von Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A, Laird, Ellen R, Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J, Choo, Edna F, Dinkel, Victoria, Feng, Bainian, Gloor, Susan L, Gould, Stephen E, Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D, Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J, Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T, Shrag, Michael, Song, Kyung, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang, Willis, Brandon S, Woessner, Richard D, Wu, Wen-I, Young, Wendy B, Grina, Jonas

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Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-RafV600E kinase with favorable physicochemical and pharmacokinetic properties von Ren, Li, Laird, Ellen R., Buckmelter, Alex J., Dinkel, Victoria, Gloor, Susan L., Grina, Jonas, Newhouse, Brad, Rasor, Kevin, Hastings, Gregg, Gradl, Stefan N., Rudolph, Joachim

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The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase von Ren, Li, Ahrendt, Kateri A., Grina, Jonas, Laird, Ellen R., Buckmelter, Alex J., Hansen, Joshua D., Newhouse, Brad, Moreno, David, Wenglowsky, Steve, Dinkel, Victoria, Gloor, Susan L., Hastings, Gregg, Rana, Sumeet, Rasor, Kevin, Risom, Tyler, Sturgis, Hillary L., Voegtli, Walter C., Mathieu, Simon

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Non-oxime inhibitors of B-Rafⱽ⁶⁰⁰ᴱ kinase von Ren, Li, Wenglowsky, Steve, Miknis, Greg, Rast, Bryson, Buckmelter, Alex J, Ely, Robert J, Schlachter, Stephen, Laird, Ellen R, Randolph, Nikole, Callejo, Michele, Martinson, Matthew, Galbraith, Sarah, Brandhuber, Barbara J, Vigers, Guy, Morales, Tony, Voegtli, Walter C, Lyssikatos, Joseph

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Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase von Newhouse, Bradley J., Wenglowsky, Steve, Grina, Jonas, Laird, Ellen R., Voegtli, Walter C., Ren, Li, Ahrendt, Kateri, Buckmelter, Alex, Gloor, Susan L., Klopfenstein, Nathalie, Rudolph, Joachim, Wen, Zhaoyang, Li, Xianfeng, Feng, Bainian

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Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors von Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A, Laird, Ellen R, Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J, Choo, Edna F, Dinkel, Victoria, Feng, Bainian, Gloor, Susan L, Gould, Stephen E, Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D, Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J, Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T, Shrag, Michael, Song, Kyung, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang, Willis, Brandon S, Woessner, Richard D, Wu, Wen-I, Young, Wendy B, Grina, Jonas

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FUSED PYRROLINES WHICH ACT AS UBIQUITIN-SPECIFIC PROTEASE 30 (USP30) INHIBITORS von BUCKMELTER, Alex J

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Non-oxime inhibitors of B-Raf super(V600E) kinase von Ren, Li, Wenglowsky, Steve, Miknis, Greg, Rast, Bryson, Buckmelter, Alex J, Ely, Robert J, Schlachter, Stephen, Laird, Ellen R, Randolph, Nikole, Callejo, Michele, Martinson, Matthew, Galbraith, Sarah, Brandhuber, Barbara J, Vigers, Guy, Morales, Tony, Voegtli, Walter C, Lyssikatos, Joseph

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Non-oxime inhibitors of B-Raf V600E kinase von Ren, Li, Wenglowsky, Steve, Miknis, Greg, Rast, Bryson, Buckmelter, Alex J., Ely, Robert J., Schlachter, Stephen, Laird, Ellen R., Randolph, Nikole, Callejo, Michele, Martinson, Matthew, Galbraith, Sarah, Brandhuber, Barbara J., Vigers, Guy, Morales, Tony, Voegtli, Walter C., Lyssikatos, Joseph

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Pyrazolopyridine inhibitors of B-Raf super(V600E. Part 2: Structure-activity relationships) von Wenglowsky, Steve, Ahrendt, Kateri A, Buckmelter, Alex J, Feng, Bainian, Gloor, Susan L, Gradl, Stefan, Grina, Jonas, Hansen, Joshua D, Laird, Ellen R, Lunghofer, Paul, Mathieu, Simon, Moreno, David, Newhouse, Brad, Ren, Li, Risom, Tyler, Rudolph, Joachim, Seo, Jeongbeob, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang

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FUSED PYRROLINES WHICH ACT AS UBIQUITIN-SPECIFIC PROTEASE 30 (USP30) INHIBITORS von Caravella, Justin Andrew, Li, Hongbin, Richard, David James, West, Angela V, Buckmelter, Alex J, Mischke, Steven, Martin, Matthew W

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Pyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors von Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A., Laird, Ellen R., Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J., Choo, Edna F., Dinkel, Victoria, Feng, Bainian, Gloor, Susan L., Gould, Stephen E., Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D., Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J., Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T., Shrag, Michael, Song, Kyung, Sturgis, Hillary L., Voegtli, Walter C., Wen, Zhaoyang, Willis, Brandon S., Woessner, Richard D., Wu, Wen-I, Young, Wendy B., Grina, Jonas

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Fused pyrrolines which act as ubiquitin-specific protease 30 (USP30) inhibitors von Caravella, Justin Andrew, Li, Hongbin, Richard, David James, West, Angela V, Buckmelter, Alex J, Mischke, Steven, Martin, Matthew W

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FUSED PYRROLINES WHICH ACT AS UBIQUITIN-SPECIFIC PROTEASE 30 (USP30) INHIBITORS von Caravella, Justin Andrew, Li, Hongbin, Richard, David James, West, Angela V, Buckmelter, Alex J, Mischke, Steven, Martin, Matthew W

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FUSED PYRROLINES WHICH ACT AS UBIQUITIN-SPECIFIC PROTEASE 30 (USP30) INHIBITORS von Caravella, Justin Andrew, Li, Hongbin, Richard, David James, West, Angela V, Buckmelter, Alex J, Mischke, Steven, Martin, Matthew W

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