Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors von Bubie, Adrian, Gonzalez-Kozlova, Edgar, Akers, Nicholas, Villanueva, Augusto, Losic, Bojan

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Landscape of oncoviral genotype and co-infection via human papilloma and hepatitis B viral tumor in situ profiling von Bubie, Adrian, Zoulim, Fabien, Testoni, Barbara, Miles, Brett, Posner, Marshall, Villanueva, Augusto, Losic, Bojan

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Does serial circulating tumor DNA (ctDNA) monitoring identify additional acquired actionable alterations in metastatic colorectal cancer (mCRC)? von Loree, Jonathan M., Bubie, Adrian, Strickler, John H, Drusbosky, Leylah, Kopetz, Scott, Raghav, Kanwal Pratap Singh

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Variation in liquid biopsy cfDNA yield predicted by somatic mutation and clinical phenotypes across primary cancers von Bubie, Adrian, Jiang, Tingting, Gaile, Daniel, Hutchins, Jamie, Drusbosky, Leylah, Kiedrowski, Lesli A., Chuang, Han-Yu

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Abstract 3415: Tumor fitness and immune exhaustion: Checkpoint vs endogenous settings von Bubie, Adrian, Akers, Nicholas, Villanueva, Augusto, Losic, Bojan

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Abstract 2130: Human papillomavirus and hepatitis B virus in situ tumor oncoviral genotype and coinfection drive oncogenesis and patient clinical response in cross cancer analysis von Bubie, Adrian P., Testoni, Barbara, Zoulim, Fabien, Miles, Brett, Posner, Marshall, Villanueva, Augusto, Losic, Bojan

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Abstract 1507: Regional DNA methylation profiling reveals novel epigenetic intra-tumoral heterogeneity signatures and aberrant molecular clocks in hepatocellular carcinoma von Bubie, Adrian, Restrepo, Paula, Craig, Amanda, Labgaa, Ismail, Schwartz, Myron, Thung, Swan, Stolovitzky, Gustavo, Losic, Bojan, Villanueva, Augusto

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Abstract 572: The liquid biopsy Guardant360 CDx has robust performance at low inputs allowing for high rate of returning patient results von Richardson, Aaron O., Hardin, Aaron, Shukla, Soni, Zhao, Jing, Barbacioru, Catalin, Beas, Hilda, Espenschied, Carin, Bubie, Adrian, Hutchins, Jamie, Chuang, Han-Yu, Jiang, Tingting, Chudova, Darya

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Abstract B071: Validating sequence similarity-driven neoepitope fitness models via immunogenomics on TCGA and multiregional tumor data von Bubie, Adrian, Akers, Nicholas, Villanueva, Augusto, Losic, Bojan

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Oncogene Overlap Analysis of Circulating Cell-free Tumor DNA to Explore the Appropriate Criteria for Defining MET Copy Number–Driven Lung Cancer von Tsui, David C.C., Drusbosky, Leylah M., Wienke, Sara, Gao, Dexiang, Bubie, Adrian, Barbacioru, Catalin, Camidge, D. Ross

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Abstract 3128: Using Kmerizer, a germline and somatic genotyper for immune associated complex alleles in GuardantINFINITY, for immunotherapy response prediction using cfDNA von Gnerre, Sante, Zhao, Jun, Bubie, Adrian, Kim, Yvonne, Ma, Dustin, Wu, Indira, Losic, Bojan, Jiang, Tingting, Chuang, Han-Yu

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Impact of Tumor-intrinsic Molecular Features on Survival and Acquired Tyrosine Kinase Inhibitor Resistance in ALK-positive NSCLC von Nakazawa, Mari, Harada, Guilherme, Ghanem, Paola, Bubie, Adrian, Kiedrowski, Lesli A, Murray, Joseph C, Marrone, Kristen A, Scott, Susan C, Houseknecht, Stefanie, Falcon, Christina J, Evans, Patrick, Feliciano, Josephine, Hann, Christine L, Ettinger, David S, Smith, Kellie N, Anagnostou, Valsamo, Forde, Patrick M, Brahmer, Julie R, Levy, Benjamin, Drilon, Alexander, Lam, Vincent K

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