Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery von Powley, Ian R., Patel, Meeta, Miles, Gareth, Pringle, Howard, Howells, Lynne, Thomas, Anne, Kettleborough, Catherine, Bryans, Justin, Hammonds, Tim, MacFarlane, Marion, Pritchard, Catrin

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Subcellular Discharge of a Serine Protease Mediates Release of Invasive Malaria Parasites from Host Erythrocytes von Yeoh, Sharon, O'Donnell, Rebecca A., Koussis, Konstantinos, Dluzewski, Anton R., Ansell, Keith H., Osborne, Simon A., Hackett, Fiona, Withers-Martinez, Chrislaine, Mitchell, Graham H., Bannister, Lawrence H., Bryans, Justin S., Kettleborough, Catherine A., Blackman, Michael J.

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Crowd sourcing in drug discovery von Lessl, Monika, Bryans, Justin S, Richards, Duncan, Asadullah, Khusru

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New anti-tuberculosis agents amongst known drugs von Lougheed, Kathryn E.A, Taylor, Debra L, Osborne, Simon A, Bryans, Justin S, Buxton, Roger S

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Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents von Lougheed, Kathryn E.A, Osborne, Simon A, Saxty, Barbara, Whalley, David, Chapman, Tim, Bouloc, Nathalie, Chugh, Jasveen, Nott, Timothy J, Patel, Dony, Spivey, Vicky L, Kettleborough, Catherine A, Bryans, Justin S, Taylor, Debra L, Smerdon, Stephen J, Buxton, Roger S

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3-Substituted GABA analogs with central nervous system activity: A review von Bryans, Justin S., Wustrow, David J.

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Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7 von Bouloc, Nathalie, Large, Jonathan M., Smiljanic, Ela, Whalley, David, Ansell, Keith H., Edlin, Christopher D., Bryans, Justin S.

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Synthesis and in vivo evaluation of bicyclic gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Carr, Christopher L., Chessum, Nicola E.A., Field, Mark J., Kinsella, Natasha, Osborne, Simon A., Warren, Andrew N., Williams, Sophie C.

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Preparation of triazolobenzodiazepine derivatives as Vasopressin V1a antagonists von Beal, David M., Bryans, Justin S., Johnson, Patrick S., Newman, Julie, Pasquinet, Christelle, Peakman, Torren M., Ryckmans, Thomas, Underwood, Toby J., Wheeler, Simon

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Metal-catalysed radical cyclisations leading to N-heterocycles: new approaches to gabapentin and pulchellalactam von Bryans, Justin S, Chessum, Nicola E.A, Huther, Nathalie, Parsons, Andrew F, Ghelfi, Franco

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Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability von Johnson, Patrick S., Ryckmans, Thomas, Bryans, Justin, Beal, Dave M., Dack, Kevin N., Feeder, Neil, Harrison, Anthony, Lewis, Mark, Mason, Helen J., Mills, James, Newman, Julie, Pasquinet, Christelle, Rawson, Dave J., Roberts, Lee R., Russell, Rachel, Spark, Deborah, Stobie, Alan, Underwood, Toby J., Ward, Robin, Wheeler, Simon

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Synthesis and in vivo evaluation of 3-substituted gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Chessum, Nicola E.A., Field, Mark J., Kinsella, Natasha, Kinsora, Jack K., Osborne, Simon A., Williams, Sophie C.

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Synthesis of highly substituted 2,6- anti-configured tetrahydropyrans. First steps towards an efficient access to amphidinol 3 ring system von Dubost, Christophe, Markó, Istvan E., Bryans, Justin

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Oxadiazolone bioisosteres of pregabalin and gabapentin von Wustrow, David J., Belliotti, Thomas R., Capiris, Thomas, Kneen, Clare O., Bryans, Justin S., Field, Mark J., Williams, Dic, El-Kattan, Ayman, Buchholz, Lisa, Kinsora, Jack J., Lotarski, Susan M., Vartanian, Mark G., Taylor, Charles P., Donevan, Sean D., Thorpe, Andrew J., Schwarz, Jacob B.

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Part 1: N-Alkylated glycines as potent α₂δ ligands von Thompson, Lisa R, Blakemore, David C, Brugier, Delphine, Bryans, Justin S, Chu, Wai-Lam A, Maw, Graham N, Poinsard, Cedric, Rawson, David J, Warren, Andrew N

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The synthesis of functionalised β- and γ-lactams by cyclisation of enamides using copper(I) or ruthenium(II) von Bryans, Justin S, Chessum, Nicola E.A, Parsons, Andrew F, Ghelfi, Franco

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Carboxylate bioisosteres of gabapentin von Burgos-Lepley, Carmen E., Thompson, Lisa R., Kneen, Clare O., Osborne, Simon A., Bryans, Justin S., Capiris, Thomas, Suman-Chauhan, Nirmala, Dooley, David J., Donovan, Cindy M., Field, Mark J., Vartanian, Mark G., Kinsora, Jack J., Lotarski, Susan M., El-Kattan, Ayman, Walters, Karen, Cherukury, Madhu, Taylor, Charles P., Wustrow, David J., Schwarz, Jacob B.

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Synthesis and in vivo evaluation of 3,4-disubstituted gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Field, Mark J., Kinsella, Natasha, Kinsora, Jack K., Meltzer, Leonard T., Osborne, Simon A., Thompson, Lisa R., Williams, Sophie C.

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A call to action for translational sciences in COVID-19 and future pandemics von Wan, Kanny K., Davis, Danielle, Lee, Taylor N., Ford-Scheimer, Stephanie L., Andreu, Antonio L., Bietrix, Florence, Bryans, Justin, Castro, Marco T., Chiba, Nobuyoshi, Faupel-Badger, Jessica M., Haynes, Brittany, Hirasawa, Ryutaro, Morel, Carlos M., Souza, Thiago Moreno L., Morrow, David, Munro, Trent, Newman, Stuart, Ussi, Anton E., Zorzal, Poliana B., Hall, Matthew D., Lo, Donald C., Cutillo, Christine M.

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Identification of Novel Ligands for the Gabapentin Binding Site on the α2δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents von Bryans, Justin S, Davies, Natasha, Gee, Nicolas S, Dissanayake, Visaka U. K, Ratcliffe, Giles S, Horwell, David C, Kneen, Clare O, Morrell, Andrew I, Oles, Ryszard J, O'Toole, John C, Perkins, Gemma M, Singh, Lakhbir, Suman-Chauhan, Nirmala, O'Neill, Jacqueline A

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